Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Aoife M, Rodgers"'
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 32 (2023)
Outer membrane vesicles (OMVs) are small, spherical structures released from the outer membranes of Gram-negative bacteria into the surrounding environment. Investigations into OMVs range from their biogenesis and cargo composition to their ability t
Externí odkaz:
https://doaj.org/article/a51c3bc62bc843a1bb49944eb76ff234
Autor:
Aoife M. Rodgers, Jaime Lindsay, Avril Monahan, Alice V. Dubois, Aduragbemi A. Faniyi, Barry J. Plant, Marcus A. Mall, Miquel B. Ekkelenkamp, Stuart Elborn, Rebecca J. Ingram
Publikováno v:
Pathogens, Vol 12, Iss 8, p 1053 (2023)
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen and the leading cause of infection in patients with cystic fibrosis (CF). The ability of P. aeruginosa to evade host responses and develop into chronic infection causes significant m
Externí odkaz:
https://doaj.org/article/ef0e5f92a6e44709bee52bd0568285e4
Autor:
Georgia Bateman, Hong Guo-Parke, Aoife M. Rodgers, Dermot Linden, Melanie Bailey, Sinéad Weldon, Joseph C. Kidney, Clifford C. Taggart
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2072 (2023)
Cellular senescence is a state of permanent cell cycle arrest triggered by various intrinsic and extrinsic stressors. Cellular senescence results in impaired tissue repair and remodeling, loss of physiological integrity, organ dysfunction, and change
Externí odkaz:
https://doaj.org/article/5b05b2bea0cf476084ed317e306b8600
Autor:
Adelaide Mensah, Aoife M. Rodgers, Eneko Larrañeta, Lyndsey McMullan, Murtaza Tambuwala, John F. Callan, Aaron J. Courtenay
Publikováno v:
Antibiotics, Vol 12, Iss 6, p 1073 (2023)
With the advancement of biomedical research into antimicrobial treatments for various diseases, the source and delivery of antibiotics have attracted attention. In periodontal diseases, antibiotics are integral in positive treatment outcomes; however
Externí odkaz:
https://doaj.org/article/7d3737fa250b4d628f71393a3ec9c31e
Autor:
Megan Osbourn, Aoife M. Rodgers, Alice V. Dubois, Donna M. Small, Fiachra Humphries, Nezira Delagic, Paul N. Moynagh, Sinéad Weldon, Clifford C. Taggart, Rebecca J. Ingram
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1728 (2022)
Secretory leucoprotease inhibitor (SLPI) has multifaceted functions, including inhibition of protease activity, antimicrobial functions, and anti-inflammatory properties. In this study, we show that SLPI plays a role in controlling pulmonary Pseudomo
Externí odkaz:
https://doaj.org/article/023d7d828d3a4ccdb3f10ca8c6e624cd
Autor:
Linan Xu, Fiachra Humphries, Nezira Delagic, Bingwei Wang, Ashling Holland, Kevin S. Edgar, Jose R. Hombrebueno, Donna Beer Stolz, Ewa Oleszycka, Aoife M. Rodgers, Nadezhda Glezeva, Kenneth McDonald, Chris J. Watson, Mark T. Ledwidge, Rebecca J. Ingram, David J. Grieve, Paul N. Moynagh
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) is a protein with roles in early development, activation of the transcription factor NF-κB, and production of mitochondrial reactive oxygen species (mROS) that facilitates clea
Externí odkaz:
https://doaj.org/article/0345bb89fc434b80b4c4d1233fd83303
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 919 (2022)
The aim of this systemic review was to collate and analyze existing data from published literature sources to identify the current understanding of the role of epigenetic and biological biomarkers in periodontal disease and diagnostics. A comprehensi
Externí odkaz:
https://doaj.org/article/e1a8d1ed64db40cf9db12838de32a541
Autor:
Ryan F. Donnelly, Ukrit Angkawinitwong, Eneko Larrañeta, Helen O. McCarthy, Aoife M. Rodgers, Aaron J. Courtenay, Gareth R. Williams, Steve Brocchini
Publikováno v:
Angkawinitwong, U, Courtenay, A J, Rodgers, A, Larraneta, E, McCarthy, H O, Brocchini, S, Donnelly, R F & Williams, G R 2020, ' A novel transdermal protein delivery strategy via electrohydrodynamic coating of PLGA microparticles onto microneedles ', ACS Applied Materials and Interfaces . https://doi.org/10.1021/acsami.9b22425
Transdermal delivery of biological therapeutics is emerging as a potent alternative to intravenous or subcutaneous injections. The latter come with major challenges including patient discomfort, the necessity for trained personnel, specialized sharps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888575a70f204c4a627fd0e1023cb2f4
https://doi.org/10.1021/acsami.9b22425
https://doi.org/10.1021/acsami.9b22425
Publikováno v:
Oleszycka, E, Rodgers, A M, Xu, L & Moynagh, P N 2021, ' Dendritic Cell-Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway ', Journal of Immunology, vol. 207, no. 9, pp. 2325-2336 . https://doi.org/10.4049/jimmunol.2100236
The Journal of Immunology Author Choice
The Journal of Immunology Author Choice
Ubiquitination regulates immune signaling, and multiple E3 ubiquitin ligases have been studied in the context of their role in immunity. Despite this progress, the physiological roles of the Pellino E3 ubiquitin ligases, especially Pellino2, in immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9418ed45dfd10b059970074ea2203e
https://pure.qub.ac.uk/en/publications/1592d775-88eb-432c-8e0d-1fa41f21d8c4
https://pure.qub.ac.uk/en/publications/1592d775-88eb-432c-8e0d-1fa41f21d8c4
Publikováno v:
Medical Devices: Evidence and Research. 12:379-398
Despite vaccination representing one of the greatest advances of modern preventative medicine, there remain significant challenges in vaccine distribution, delivery and compliance. Dissolvable microarray patches or dissolving microneedles (DMN) have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::351fc646d8d04f73b09f9bb36c1f8fac
https://doi.org/10.2147/mder.s198220
https://doi.org/10.2147/mder.s198220