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pro vyhledávání: '"Aoife Kerrin"'
Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis
Autor:
Paul M. Fitch, Jon McCormack, Liz Waxman, Armin Braun, Richard Levin, Jürgen Schwarze, Sabine Wronski, Claire Errington, Ulf Theilen, Aoife Kerrin, Karen J. Mackenzie, Kay Riding, Henry J. McSorley, Dennis Kerr, Felicity Mehendele
Publikováno v:
Kerrin, A, Fitch, P, Errington, C, Kerr, D, Waxman, L, Riding, K, McCormack, J, Mehendale, F, McSorley, H, Mackenzie, K, Wronski, S, Braun, A, Leven, R, Theilen, U & Schwarze, J 2017, ' Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis ', Thorax, vol. 72, no. 7, pp. 620-627 . https://doi.org/10.1136/thoraxjnl-2015-207358
Rationale The pathogenesis of respiratory syncytial virus (RSV) bronchiolitis in infants remains poorly understood. Mouse models implicate pulmonary T cells in the development of RSV disease. T cell responses are initiated by dendritic cells (DCs), w
Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury
Autor:
Daniel F. McAuley, Sinéad Weldon, Thelma R. Craig, Aoife Kerrin, A. John Simpson, Allen Hung-Kang Chung, Clifford C. Taggart, Cecilia O'Kane
Publikováno v:
Thorax. 68(4)
Rationale We hypothesise that elafin levels in acute lung injury (ALI) decrease over time due, in part, to proteolytic degradation as observed in other lung diseases. Objectives The aim of this study was to characterise temporal changes in elafin con
Autor:
Murali Shyamsundar, Cecilia O'Kane, Aoife Kerrin, Daniel F. McAuley, Clifford C. Taggart, Thelma R. Craig
Publikováno v:
C13. PATHOGENESIS OF ACUTE LUNG INJURY.
Autor:
Simon J. H. Brookes, Aoife Kerrin, Vladimir P. Zagorodnyuk, Melodie Muto, Nick J. Spencer, Orla McDonnell, Grant W. Hennig
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(4)
The mechanosensitive endings of low-threshold, slowly adapting pelvic afferents that innervate the rectum have been previously identified as rectal intraganglionic laminar endings (rIGLEs) that lie within myenteric ganglia. We tested whether the agan
Publikováno v:
Thorax. 65:A47-A48
Introduction Unregulated protease activity is implicated in the pathogenesis of acute lung injury (ALI). Elafin is a potent serine protease inhibitor produced by epithelial and inflammatory cells with anti-inflammatory actions. Aim To assess the temp
Autor:
Spencer, Nick J., Kerrin, Aoife, Zagorodnyuk, Vladimir P., Hennig, Grant W., Muto, Melodie, Brookes, Simon J., McDonnell, Orla
Publikováno v:
American Journal of Physiology: Gastrointestinal & Liver Physiology; Apr2008, Vol. 294, pG855-G867, 13p, 20 Black and White Photographs, 1 Diagram, 1 Chart, 34 Graphs