Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aoife Griffin"'
Autor:
Sara Larivière, Jessica Royer, Raúl Rodríguez-Cruces, Casey Paquola, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon S. Keller, Fernando Cendes, Clarissa L. Yasuda, Leonardo Bonilha, Ezequiel Gleichgerrcht, Niels K. Focke, Martin Domin, Felix von Podewills, Soenke Langner, Christian Rummel, Roland Wiest, Pascal Martin, Raviteja Kotikalapudi, Terence J. O’Brien, Benjamin Sinclair, Lucy Vivash, Patricia M. Desmond, Elaine Lui, Anna Elisabetta Vaudano, Stefano Meletti, Manuela Tondelli, Saud Alhusaini, Colin P. Doherty, Gianpiero L. Cavalleri, Norman Delanty, Reetta Kälviäinen, Graeme D. Jackson, Magdalena Kowalczyk, Mario Mascalchi, Mira Semmelroch, Rhys H. Thomas, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Junsong Zhang, Gavin P. Winston, Aoife Griffin, Aditi Singh, Vijay K. Tiwari, Barbara A. K. Kreilkamp, Matteo Lenge, Renzo Guerrini, Khalid Hamandi, Sonya Foley, Theodor Rüber, Bernd Weber, Chantal Depondt, Julie Absil, Sarah J. A. Carr, Eugenio Abela, Mark P. Richardson, Orrin Devinsky, Mariasavina Severino, Pasquale Striano, Domenico Tortora, Erik Kaestner, Sean N. Hatton, Sjoerd B. Vos, Lorenzo Caciagli, John S. Duncan, Christopher D. Whelan, Paul M. Thompson, Sanjay M. Sisodiya, Andrea Bernasconi, Angelo Labate, Carrie R. McDonald, Neda Bernasconi, Boris C. Bernhardt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Epilepsy is a brain network disorder with associated genetic risk factors. Here, the authors show that spatial patterns of transcriptomic vulnerability co-vary with structural brain network alterations in focal and generalized epilepsy.
Externí odkaz:
https://doaj.org/article/42a2adc39a114a5faf720bcffa41fabd
Autor:
Sara Larivière, Jessica Royer, Raúl Rodríguez-Cruces, Casey Paquola, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon S. Keller, Fernando Cendes, Clarissa L. Yasuda, Leonardo Bonilha, Ezequiel Gleichgerrcht, Niels K. Focke, Martin Domin, Felix von Podewills, Soenke Langner, Christian Rummel, Roland Wiest, Pascal Martin, Raviteja Kotikalapudi, Terence J. O’Brien, Benjamin Sinclair, Lucy Vivash, Patricia M. Desmond, Elaine Lui, Anna Elisabetta Vaudano, Stefano Meletti, Manuela Tondelli, Saud Alhusaini, Colin P. Doherty, Gianpiero L. Cavalleri, Norman Delanty, Reetta Kälviäinen, Graeme D. Jackson, Magdalena Kowalczyk, Mario Mascalchi, Mira Semmelroch, Rhys H. Thomas, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Junsong Zhang, Gavin P. Winston, Aoife Griffin, Aditi Singh, Vijay K. Tiwari, Barbara A. K. Kreilkamp, Matteo Lenge, Renzo Guerrini, Khalid Hamandi, Sonya Foley, Theodor Rüber, Bernd Weber, Chantal Depondt, Julie Absil, Sarah J. A. Carr, Eugenio Abela, Mark P. Richardson, Orrin Devinsky, Mariasavina Severino, Pasquale Striano, Domenico Tortora, Erik Kaestner, Sean N. Hatton, Sjoerd B. Vos, Lorenzo Caciagli, John S. Duncan, Christopher D. Whelan, Paul M. Thompson, Sanjay M. Sisodiya, Andrea Bernasconi, Angelo Labate, Carrie R. McDonald, Neda Bernasconi, Boris C. Bernhardt
Publikováno v:
Nature Communications
Larivière, Sara; Royer, Jessica; Rodríguez-Cruces, Raúl; Paquola, Casey; Caligiuri, Maria Eugenia; Gambardella, Antonio; Concha, Luis; Keller, Simon S; Cendes, Fernando; Yasuda, Clarissa L; Bonilha, Leonardo; Gleichgerrcht, Ezequiel; Focke, Niels K; Domin, Martin; von Podewills, Felix; Langner, Soenke; Rummel, Christian; Wiest, Roland; Martin, Pascal; Kotikalapudi, Raviteja; ... (2022). Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. Nature Communications, 13(1), p. 4320. Springer Nature 10.1038/s41467-022-31730-5
Larivière, S, Royer, J, Rodríguez-Cruces, R, Paquola, C, Caligiuri, M E, Gambardella, A, Concha, L, Keller, S S, Cendes, F, Yasuda, C L, Bonilha, L, Gleichgerrcht, E, Focke, N K, Domin, M, von Podewills, F, Langner, S, Rummel, C, Wiest, R, Martin, P, Kotikalapudi, R, O'Brien, T J, Sinclair, B, Vivash, L, Desmond, P M, Lui, E, Vaudano, A E, Meletti, S, Tondelli, M, Alhusaini, S, Doherty, C P, Cavalleri, G L, Delanty, N, Kälviäinen, R, Jackson, G D, Kowalczyk, M, Mascalchi, M, Semmelroch, M, Thomas, R H, Soltanian-Zadeh, H, Davoodi-Bojd, E, Zhang, J, Winston, G P, Griffin, A, Singh, A, Tiwari, V K, Kreilkamp, B A K, Lenge, M, Guerrini, R, Hamandi, K, Foley, S, Rüber, T, Weber, B, Depondt, C, Absil, J, Carr, S J A, Abela, E, Richardson, M P, Devinsky, O, Severino, M, Striano, P, Tortora, D, Kaestner, E, Hatton, S N, Vos, S B, Caciagli, L, Duncan, J S, Whelan, C D, Thompson, P M, Sisodiya, S M, Bernasconi, A, Labate, A, McDonald, C R, Bernasconi, N & Bernhardt, B C 2022, ' Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression ', Nature Communications, vol. 13, 4320 . https://doi.org/10.1038/s41467-022-31730-5
Nature Communications 13(1), 4320 (2022). doi:10.1038/s41467-022-31730-5
Nature communications, vol 13, iss 1
Larivière, Sara; Royer, Jessica; Rodríguez-Cruces, Raúl; Paquola, Casey; Caligiuri, Maria Eugenia; Gambardella, Antonio; Concha, Luis; Keller, Simon S; Cendes, Fernando; Yasuda, Clarissa L; Bonilha, Leonardo; Gleichgerrcht, Ezequiel; Focke, Niels K; Domin, Martin; von Podewills, Felix; Langner, Soenke; Rummel, Christian; Wiest, Roland; Martin, Pascal; Kotikalapudi, Raviteja; ... (2022). Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. Nature Communications, 13(1), p. 4320. Springer Nature 10.1038/s41467-022-31730-5
Larivière, S, Royer, J, Rodríguez-Cruces, R, Paquola, C, Caligiuri, M E, Gambardella, A, Concha, L, Keller, S S, Cendes, F, Yasuda, C L, Bonilha, L, Gleichgerrcht, E, Focke, N K, Domin, M, von Podewills, F, Langner, S, Rummel, C, Wiest, R, Martin, P, Kotikalapudi, R, O'Brien, T J, Sinclair, B, Vivash, L, Desmond, P M, Lui, E, Vaudano, A E, Meletti, S, Tondelli, M, Alhusaini, S, Doherty, C P, Cavalleri, G L, Delanty, N, Kälviäinen, R, Jackson, G D, Kowalczyk, M, Mascalchi, M, Semmelroch, M, Thomas, R H, Soltanian-Zadeh, H, Davoodi-Bojd, E, Zhang, J, Winston, G P, Griffin, A, Singh, A, Tiwari, V K, Kreilkamp, B A K, Lenge, M, Guerrini, R, Hamandi, K, Foley, S, Rüber, T, Weber, B, Depondt, C, Absil, J, Carr, S J A, Abela, E, Richardson, M P, Devinsky, O, Severino, M, Striano, P, Tortora, D, Kaestner, E, Hatton, S N, Vos, S B, Caciagli, L, Duncan, J S, Whelan, C D, Thompson, P M, Sisodiya, S M, Bernasconi, A, Labate, A, McDonald, C R, Bernasconi, N & Bernhardt, B C 2022, ' Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression ', Nature Communications, vol. 13, 4320 . https://doi.org/10.1038/s41467-022-31730-5
Nature Communications 13(1), 4320 (2022). doi:10.1038/s41467-022-31730-5
Nature communications, vol 13, iss 1
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations, but associations between neurobiological mechanisms and macroscale connectomics remain unclear. This multisite ENIGMA-Epilepsy study examined whole-brain st
Publikováno v:
Griffin, A, Mahesh, A & Tiwari, V K 2022, ' Disruption of the gene regulatory programme in neurodevelopmental disorders ', Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, vol. 1865, no. 7, 194860 . https://doi.org/10.1016/j.bbagrm.2022.194860
Cortical development consists of a series of synchronised events, including fate transition of cortical progenitors, neuronal migration, specification and connectivity. It is becoming clear that gene expression programs governing these events rely on