Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aoi Kakehi"'
Autor:
Dai Yuki, Akira Kikuchi, Takuya Suzuki, Chikako Sakaguchi, Danting Huangfu, Yasufumi Nagata, Aoi Kakehi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The objectives of this clinical study were to demonstrate a reduction in exposure to selected harmful and potentially harmful constituents (HPHCs) in Japanese healthy adult smokers who switched to four in-market heated tobacco products. Eigh
Externí odkaz:
https://doaj.org/article/baf7d2d108e54b719b2294149eae88fb
Publikováno v:
Regulatory Toxicology and Pharmacology. 69:338-347
The objective of this clinical study was to investigate changes in levels of biomarkers of exposure (BOEs) in healthy Japanese male smokers who switched to a prototype heated cigarette (HC). This was a controlled, semi-randomized, open-label, residen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274e8ef1e64684650535e993a17ac72d
https://doi.org/10.1016/j.yrtph.2014.04.016
https://doi.org/10.1016/j.yrtph.2014.04.016
Publikováno v:
Regulatory Toxicology and Pharmacology. 67:240-245
This study investigated the relationship between plasma and saliva cotinine kinetics after smoking one cigarette and the relationship between cotinine kinetics and estimated nicotine intake, which was calculated as mouth level exposure (MLE) of nicot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adfff259ec843956b1304b3099323f6
https://doi.org/10.1016/j.yrtph.2013.08.002
https://doi.org/10.1016/j.yrtph.2013.08.002
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 71(3)
In a clinical study, changes in 14 biomarkers of exposures (BOEs) from 10 tobacco smoke constituents and mutagens detected by the urine mutagenicity test were investigated using a non-combustion inhaler type of tobacco product (NCIT) by switching fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42245acb05d7a850b33c70851ff6eab8
https://pubmed.ncbi.nlm.nih.gov/25683775
https://pubmed.ncbi.nlm.nih.gov/25683775
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 67(2)
In a clinical study, the pharmacokinetics of nicotine were investigated using the prototype of a non-combustion inhaler type of tobacco product (PNCIT) with comparison to a 1mg tar conventional cigarette (CC). The study was conducted in 12 healthy ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4387d8fd6d441af898400fc94d2ce4d
https://pubmed.ncbi.nlm.nih.gov/23891672
https://pubmed.ncbi.nlm.nih.gov/23891672
Autor:
Chikako Sakaguchi1 chikako.sakaguchi@jt.com, Aoi Kakehi1, Naoki Minami1, Akira Kikuchi1, Yasuyuki Futamura1
Publikováno v:
Regulatory Toxicology & Pharmacology: RTP. Aug2014, Vol. 69 Issue 3, p338-347. 10p.