Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anzor Gvritishvili"'
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133777 (2015)
Our recent publication showed that a small bioactive pigment epithelium derived factor (PEDF) peptide (P78-PEDF) prevents the development of diabetic nephropathy (DN). However, its effects on the progression of established DN were not clear. Therefor
Externí odkaz:
https://doaj.org/article/ad11a2b3174745c988c95fa11d2d0d3f
Autor:
Ana Rubin Panvini, Anzor Gvritishvili, Hannah Galvan, Sonali Nashine, Shari R. Atilano, M. Cristina Kenney, Joyce Tombran-Tink
Publikováno v:
Exp Eye Res
Mitochondrial dysfunction is associated with several retinal degenerative diseases including Age-related Macular Degeneration (AMD). Human mitochondrial DNA (mtDNA) haplogroups are inherited from a common ancestral clan and are defined by specific se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad46945c7055c7d82f010683be4411c
https://doi.org/10.1016/j.exer.2022.109013
https://doi.org/10.1016/j.exer.2022.109013
Publikováno v:
Sleep. 42:A1-A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23fabaa7b6acb6ae7299907be2589f70
https://doi.org/10.1093/sleep/zsz067.000
https://doi.org/10.1093/sleep/zsz067.000
Autor:
W. Brian Reeves, Timothy K. Cooper, Hanning You, Yanling Liu, Ting Gao, Alaa S. Awad, Joyce Tombran-Tink, Anzor Gvritishvili
Publikováno v:
American Journal of Physiology-Renal Physiology. 305:F891-F900
Pigment epithelium-derived factor (PEDF) is a multifunctional protein with antiangiogenic, antioxidative, and anti-inflammatory properties. PEDF is involved in the pathogenesis of diabetic retinopathy, but its direct role in the kidneys remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fac55e58ee1a0f86eafb7d3164b8a93
https://doi.org/10.1152/ajprenal.00149.2013
https://doi.org/10.1152/ajprenal.00149.2013
Publikováno v:
Journal of Molecular Neuroscience. 46:122-137
Decreases in systemic and cellular levels of zinc (Zn(2+)) during normal aging correlate with several age-related pathologies including age-related macular degeneration. Zn(2+) homeostasis in tissues is not only dependent on dietary intake but also o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f52630264a32111c9a378e0f9537546
https://doi.org/10.1007/s12031-011-9536-0
https://doi.org/10.1007/s12031-011-9536-0
Autor:
Timothy K. Cooper, Alaa S. Awad, Hanning You, Joyce Tombran-Tink, Anzor Gvritishvili, Ting Gao
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133777 (2015)
PLoS ONE
PLoS ONE
Our recent publication showed that a small bioactive pigment epithelium derived factor (PEDF) peptide (P78-PEDF) prevents the development of diabetic nephropathy (DN). However, its effects on the progression of established DN were not clear. Therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cdf146f0e555389e7d40e1de6050c1
http://europepmc.org/articles/PMC4514848?pdf=render
http://europepmc.org/articles/PMC4514848?pdf=render
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e15056 (2010)
PLoS ONE, Vol 5, Iss 11, p e15056 (2010)
Pigment epithelium-derived factor (PEDF) is widely known for its neurotrophic and antiangiogenic functions. Efficacy studies of PEDF in animal models are limited because of poor heterologous protein yields. Here, we redesigned the human PEDF gene to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d536fbcd900d0b30dd732bc6b5d276
https://pubmed.ncbi.nlm.nih.gov/21152082
https://pubmed.ncbi.nlm.nih.gov/21152082
Publikováno v:
Protein science : a publication of the Protein Society. 17(7)
The energetic contribution of complex salt bridges, in which one charged residue (anchor residue) forms salt bridges with two or more residues simultaneously, has been suggested to have importance for protein stability. Detailed analysis of the net e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc2b39a71fa65ed9a5b8a28d9856507
https://pubmed.ncbi.nlm.nih.gov/18469176
https://pubmed.ncbi.nlm.nih.gov/18469176
Autor:
Bindi Dangi, Angela M. Gronenborn, George I. Makhatadze, Dmitri N. Ermolenko, Anzor Gvritishvili
Publikováno v:
Biophysical chemistry. 126(1-3)
Single amino acid substitutions rarely produce substantial changes in protein structure. Here we show that substitution of the C-cap residue in the alpha-helix of ubiquitin with proline (34P variant) leads to dramatic structural changes. The resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b38316c6464695551f663b2028aa9dd
https://pubmed.ncbi.nlm.nih.gov/16713063
https://pubmed.ncbi.nlm.nih.gov/16713063