Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anzhela V. Pavlova"'
Autor:
Anzhela V. Pavlova, Victoria Yu. Savitskaya, Nina G. Dolinnaya, Mayya V. Monakhova, Anastasia V. Litvinova, Elena A. Kubareva, Maria I. Zvereva
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1871 (2022)
G-quadruplexes (G4s) are a unique class of noncanonical DNAs that play a key role in cellular processes and neoplastic transformation. Herein, we focused on the promoter region of human TERT oncogene, whose product is responsible for the immortality
Externí odkaz:
https://doaj.org/article/ea5ae07ea1ef4a8f97a2c329e048a38f
Autor:
Anzhela V. Pavlova, Elena A. Kubareva, Mayya V. Monakhova, Maria I. Zvereva, Nina G. Dolinnaya
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1284 (2021)
DNA G-quadruplexes (G4s) are known to be an integral part of the complex regulatory systems in both normal and pathological cells. At the same time, the ability of G4s to impede DNA replication plays a critical role in genome integrity. This review s
Externí odkaz:
https://doaj.org/article/31581047bcb8426c8ab987ec712e2f66
Autor:
Anzhela V. Pavlova, Nina G. Dolinnaya, Maria I. Zvereva, Elena A. Kubareva, Mayya V. Monakhova
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1061
G-quadruplexes (G4s), the most widely studied alternative DNA structures, are implicated in the regulation of the key cellular processes. In recent years, their involvement in DNA repair machinery has become the subject of intense research. Here, we
Autor:
Natalia A. Andreeva, M. V. Monakhova, Marianna G. Yakubovskaya, Elena A. Kubareva, Maria I. Zvereva, Gennady Yu. Laptev, Nina G. Dolinnaya, Anna M. Ogloblina, Tatiana S. Oretskaya, Vladimir I. Polshakov, Elizaveta S. Gromova, Anzhela V. Pavlova
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8773, p 8773 (2020)
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8773, p 8773 (2020)
DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact o
Autor:
Anzhela V. Pavlova, Gabriele Klug, Andrei V. Alexeevski, Vladimir G. Lunin, Peter Friedhoff, M. V. Monakhova, Elena A. Kubareva, A I Penkina, T. S. Oretskaya, V V Kucherenko, A M Lyaschuk
Publikováno v:
Biochemistry (Moscow). 83:281-293
We have purified the MutL protein from Rhodobacter sphaeroides mismatch repair system (rsMutL) for the first time. rsMutL demonstrated endonuclease activity in vitro, as predicted by bioinformatics analysis. Based on the alignment of 1483 sequences o