Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib

Autor: Anyue Yin, G. D. Marijn Veerman, Johan G. C. vanHasselt, Christi M. J. Steendam, Hendrikus Jan Dubbink, Henk‐Jan Guchelaar, Lena E. Friberg, Anne‐Marie C. Dingemans, Ron H. J. Mathijssen, Dirk Jan A. R. Moes

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 4, Pp 612-623 (2024)

Abstract Insight into the development of treatment resistance can support the optimization of anticancer treatments. This study aims to characterize the tumor dynamics and development of drug resistance in patients with non‐small cell lung cancer t

Externí odkaz: https://doaj.org/article/ea749281c095497bbf69f8fe06f78a32

Publisher Correction: Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

Autor: Anyue Yin, Johan G. C. van Hasselt, Henk-Jan Guchelaar, Lena E. Friberg, Dirk Jan A. R. Moes

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-2 (2022)

Externí odkaz: https://doaj.org/article/fa287f3e6e3c4d4f86bf8631be5970fa

Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing

Autor: Eleonora P M Corssmit, Thomas M.A. Kerkhofs, Henri J L M Timmers, Marelise Eekhoff, Liselotte van Deun, Henk-Jan Guchelaar, Michiel N. Kerstens, Hans Gelderblom, Anyue Yin, Jesse J. Swen, Antonio D'Avolio, Madeleine H.T. Ettaieb, Dirk Jan A.R. Moes, Robert J.H.M. van der Straaten, Richard A Feelders, Jessica Cusato, Harm R. Haak

Publikováno v: Clinical Pharmacokinetics
Clinical Pharmacokinetics, 60, 89-102
Yin, A, Ettaieb, M H T, Swen, J J, van Deun, L, Kerkhofs, T M A, van der Straaten, R J H M, Corssmit, E P M, Gelderblom, H, Kerstens, M N, Feelders, R A, Eekhoff, M, Timmers, H J L M, D’Avolio, A, Cusato, J, Guchelaar, H J, Haak, H R & Moes, D J A R 2021, ' Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma : Towards Individualized Dosing ', Clinical Pharmacokinetics, vol. 60, no. 1, pp. 89-102 . https://doi.org/10.1007/s40262-020-00913-y
Clinical Pharmacokinetics, 60(1), 89-102. Adis International Ltd
Clinical Pharmacokinetics, 89-102. Springer International Publishing AG
ISSUE=1;STARTPAGE=89;ENDPAGE=102;ISSN=0312-5963;TITLE=Clinical Pharmacokinetics
Clinical Pharmacokinetics, 60(1), 89-102. Adis
Clinical Pharmacokinetics, 60, 1, pp. 89-102
Clinical Pharmacokinetics, 60, 89-102. ADIS INT LTD

Background Mitotane is the only approved treatment for patients with adrenocortical carcinoma (ACC). A better explanation for the variability in the pharmacokinetics (PK) of mitotane, and the optimization and individualization of mitotane treatment,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a96040ee3ce7635be4ded6e6cc14c5
http://hdl.handle.net/2318/1788848

A Review of Mathematical Models for Tumor Dynamics and Treatment Resistance Evolution of Solid Tumors

Autor: Dirk Jan A.R. Moes, Johan G.C. van Hasselt, Jesse J. Swen, Henk-Jan Guchelaar, Anyue Yin

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics and Systems Pharmacology, 8(10), 720-737. WILEY
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 10, Pp 720-737 (2019)

Increasing knowledge of intertumor heterogeneity, intratumor heterogeneity, and cancer evolution has improved the understanding of anticancer treatment resistance. A better characterization of cancer evolution and subsequent use of this knowledge for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8522bf89a1536bf4fac910fbdb92ca5c
https://hdl.handle.net/1887/122399

[Population pharmacokinetics of ciprofloxacin in Chinese elderly patients with lower respiratory tract infection]

Autor: Xiaoyan, Gai, Ning, Shen, Bei, He, Qingtao, Zhou, Shining, Bo, Xiaoguang, Li, Suodi, Zhai, Anyue, Yin, Wei, Lu

Publikováno v: Zhonghua yi xue za zhi. 95(20)

To analyse population pharmacokinetic (PPK) parameter values of ciprofloxacin in Chinese elderly patients with lower respiratory tract infection.Hospitalized in Respiratory Intensive Care Unit (RICU) due to severe lower respiratory tract infection an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9c3e1cff936192d0e689db0cb3cd2c3
https://pubmed.ncbi.nlm.nih.gov/26463606