Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anya Polovina"'
Autor:
Jason Ho, Chelsie Macedo, Garrett Cyprus, Rajay Pandit, Anya Polovina, Nadja Kern, Abrahim Hussain, Sae Jeong Ahn, William Crago, Emily Rowell, Florian J Sulzmaier, John C Timmer, Brendan P Eckelman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background As a major driver of lymphocyte proliferation and activation interleukin 2 (IL-2) is a crucial mediator for antitumor responses. Despite promising activity in a subset of patients, wider therapeutic utility of IL-2 (aldesleukin) has been h
Externí odkaz:
https://doaj.org/article/1128664e4a4f45238e95ab92d708e9bf
Autor:
Robert Tacke, Josh Sun, Satoshi Uchiyama, Anya Polovina, Deborah G. Nguyen, Victor Nizet, Stijn van der Veen
Publikováno v:
Infectious Microbes & Diseases, Vol 1, Iss 2, Pp 61-69 (2019)
Abstract. Multidrug-resistant (MDR) bacterial infections exert a tremendous burden on the public health system throughout the developing and developed world. Slowing development of novel antibiotic scaffolds, over-prescription of antibiotics, extensi
Externí odkaz:
https://doaj.org/article/040e910f756048e49d598ca6e856cb3d
Autor:
Heather Kinkead, Chelsie Macedo, Angelica Sanabria, Rajay Pandit, Florian Sulzmaier, John Timmer, Brendan Eckelman, Analeah Heidt, Anya Polovina, Nadja Kern, Abrahim Hussain, Sae Jeong Ahn, William Crago
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/c3600c19b90545af82b567ddd7c57bd7
Autor:
Florian J Sulzmaier, Nadja Kern, Sae Jeong Ahn, Anya Polovina, Jason Ho, Abrahim Hussain, Garrett Cyprus, Chelsie Macedo, Rajay Pandit, William Crago, Emily Rowell, John C Timmer, Brendan P Eckelman
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006116
BackgroundAs a major driver of lymphocyte proliferation and activation interleukin 2 (IL-2) is a crucial mediator for antitumor responses. Despite promising activity in a subset of patients, wider therapeutic utility of IL-2 (aldesleukin) has been ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb63a7d2dee966e640f9980c428d7b5
https://doi.org/10.1136/jitc-2022-006116
https://doi.org/10.1136/jitc-2022-006116
Autor:
Angelica Sanabria, Heather Kinkead, Rajay Pandit, Florian Sulzmaier, Chelsie Macedo, Sae Jeong Ahn, Brendan P. Eckelman, Crago William, Anya Polovina, Nadja Kern, Timmer John C, Abrahim Hussain, Analeah Heidt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundNatural Killer (NK) cells play a pivotal role in cancer immunosurveillance due to their potent cytolytic activity and NK cell-centric therapies have emerged as safer alternatives to targeting T cells.1 2 Interleukin 2 (IL-2) drives NK cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc00451d5dae8c0accc275ccfa7ee4df
https://doaj.org/article/c3600c19b90545af82b567ddd7c57bd7
https://doaj.org/article/c3600c19b90545af82b567ddd7c57bd7
Autor:
Heather Kinkead, Florian J. Sulzmaier, Anya Polovina, Nadja Kern, Angelica Sanabria, Jason Ho, Chelsie Macedo, Ryan Henderson, Abrahim Hussain, Rajay Pandit, William Crago, Emily Rowell, Brendan P. Eckelman
Publikováno v:
Cancer Research. 82:3513-3513
IL-2 is a powerful cytokine that enhances the activity of and induces the expansion of tumoricidal effector cells including T and NK cells. Despite promising signs of activity, the clinical utility of IL-2 is limited due to severe treatment-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc43523f8c9f6e6ffb54f9ffec3bfc9d
https://doi.org/10.1158/1538-7445.am2022-3513
https://doi.org/10.1158/1538-7445.am2022-3513