Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Anwar Anwar-Mohamed"'
Autor:
Marilyn Gordon, Mohamed El-Kalla, Yuewen Zhao, Yahya Fiteih, Jennifer Law, Natalia Volodko, Anwar Anwar-Mohamed, Ayman O. S. El-Kadi, Lei Liu, Jeff Odenbach, Aducio Thiesen, Christina Onyskiw, Haya Abu Ghazaleh, Jikyoung Park, Sean Bong Lee, Victor C. Yu, Carlos Fernandez-Patron, R. Todd Alexander, Eytan Wine, Shairaz Baksh
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/f98a7c87eb584c82b93c329c7101fa51
Autor:
Marilyn Gordon, Mohamed El-Kalla, Yuewen Zhao, Yahya Fiteih, Jennifer Law, Natalia Volodko, Anwar Anwar-Mohamed, Ayman O S El-Kadi, Lei Liu, Jeff Odenbach, Aducio Thiesen, Christina Onyskiw, Haya Abu Ghazaleh, Jikyoung Park, Sean Bong Lee, Victor C Yu, Carlos Fernandez-Patron, R Todd Alexander, Eytan Wine, Shairaz Baksh
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75483 (2013)
Ras association domain family protein 1A (RASSF1A) is a tumor suppressor gene silenced in cancer. Here we report that RASSF1A is a novel regulator of intestinal inflammation as Rassf1a(+/-) , Rassf1a(-/-) and an intestinal epithelial cell specific kn
Externí odkaz:
https://doaj.org/article/e78ee580fad54e638725756a962f1619
Publikováno v:
Assiut Scientific Nursing Journal. 6:36-48
Background: Maternal-fetal attachment (MFA) plays an important role in the maternal and fetal well-being. Despite the presence of consistent evidence about individual differences in the level of MFA, there is still a need to identify the most salient
Autor:
Gavin E. Arteel, Anwar Anwar-Mohamed, Amanda N. Douglas, Craig J. McClain, Keith C. Falkner, Bradford G. Hill, Lisanne C. Anders, Juliane I. Beier, Anna L. Lang, Matthew C. Cave, Nikole L. Warner, Adrienne M. Bushau
Publikováno v:
Toxicological Sciences. 151:312-323
Vinyl chloride (VC) is a ubiquitous environmental contaminant for which human risk is incompletely understood. We have previously reported that high occupational exposure to VC directly caused liver damage in humans. However, whether VC may also pote
Autor:
Ayman O.S. El-Kadi, Dalia A. Hamdy, Dion R. Brocks, Anwar Anwar-Mohamed, Hesham M. Korashy, Ahmed A. El-Sherbeni
Publikováno v:
Journal of Pharmaceutical Sciences. 105:1318-1326
Ketoconazole (KTZ) has 2 chiral centers with the therapeutically active form being a racemic mixture of 2 cis-enantiomers, namely, (2R,4S)-(+)-KTZ and (2S,4R)-(-)-KTZ. The aims of the present study were to examine the effects of (+)-KTZ, (-)-KTZ, and
Autor:
Jamie T. Lewis, William R. Addison, Anwar Anwar-Mohamed, Donna N. Douglas, Christopher Hao Pu, Rakesh Bhat, Garry Lund, Michael Logan, Norman M. Kneteman, Richard Lehner
Publikováno v:
Journal of Biological Chemistry. 291:1974-1990
Cytopathic effects are currently believed to contribute to hepatitis C virus (HCV)-induced liver injury and are readily observed in Huh7.5 cells infected with the JFH-1 HCV strain, manifesting as apoptosis highly correlated with growth arrest. Reacti
Autor:
Mohamed Abdelrady, Osama H. Elshenawy, Anwar Anwar-Mohamed, Ayman O.S. El-Kadi, Ahmed A. El-Sherbeni
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 92:693-702
The toxic effects of arsenic on the whole brain, as well as the discrete regions, has been previously reported for mice. We investigated the effects of acute arsenite (As(III)) on brain levels of arachidonic acid (AA) and its associated metabolites g
Publikováno v:
Current Drug Metabolism. 14:706-719
Arachidonic acid (AA) is metabolized by enzymes of the cytochrome P450 (CYP) 4A and CYP4F subfamilies to 20- hydroxyeicosatetraeonic acid (20-HETE), which plays an important role in the cardiovascular system. In the current work, we reviewed the form
Publikováno v:
Free Radical Biology and Medicine. 58:52-63
Heavy metals, typified by arsenite (As(III)), have been implicated in altering the carcinogenicity of aryl hydrocarbon receptor (AhR) ligands, typified by 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD), by modulating the induction of the Cyp1a1 enzyme,
Publikováno v:
Drug Metabolism and Disposition. 40:504-514
Heme oxygenase (HO-1), the rate-limiting enzyme in the physiological breakdown of heme, is ubiquitous, and its expression can be increased by arsenite [As(III)], and similar other stimuli that induce cellular oxidative stress. Interestingly, it has b