The molecular effects of Asperuloside against thermogenesis and anti-inflammatory process through multiple recent obesity pathways: An anti-obesity drug discovery by in-silico analysis

Autor: Aftab Ahmad, Asif Husain, Mohammed F. Abuzinadah, Anwar A. Alghamdi, Varish Ahmad, Rasheed A. Shaik, Basma G. Eid

Publikováno v: Journal of King Saud University: Science, Vol 35, Iss 8, Pp 102897- (2023)

Objectives: Adenosine receptor signaling and suppressing potential pathways such as the aryl hydrocarbon receptor (AHR) and takeda G-protein-coupled receptor-5(TGR5) have been identified as potential targets for enhancing metabolic health. Certain ad

Externí odkaz: https://doaj.org/article/f1a0f25168674c4c9404a34e562be7fe

Anti-Fibrotic Efficacy of Apigenin in a Mice Model of Carbon Tetrachloride-Induced Hepatic Fibrosis by Modulation of Oxidative Stress, Inflammation, and Fibrogenesis: A Preclinical Study

Autor: Maryam Melaibari, Huda M. Alkreathy, Ahmed Esmat, Nisreen A. Rajeh, Rasheed A. Shaik, Anwar A. Alghamdi, Aftab Ahmad

Publikováno v: Biomedicines, Vol 11, Iss 5, p 1342 (2023)

Background: Hepatic fibrosis is a major health problem all over the world, and there is no effective treatment to cure it. Hence, the current study sought to assess the anti-fibrotic efficacy of apigenin against CCl4-induced hepatic fibrosis in mice.

Externí odkaz: https://doaj.org/article/48a5f1f08d3b406695e63f2a98a56217

Chemistry and Pharmacological Actions of Delphinidin, a Dietary Purple Pigment in Anthocyanidin and Anthocyanin Forms

Autor: Asif Husain, Harshit Chanana, Shah Alam Khan, U. M. Dhanalekshmi, M. Ali, Anwar A. Alghamdi, Aftab Ahmad

Publikováno v: Frontiers in Nutrition, Vol 9 (2022)

Anthocyanins are naturally occurring water-soluble flavonoids abundantly present in fruits and vegetables. They are polymethoxyderivatives of 2-phenyl-benzopyrylium or flavylium salts. Delphinidin (Dp) is a purple-colored plant pigment, which occurs

Externí odkaz: https://doaj.org/article/c81bba1da0d84e4db58c22101f1e53a1

Incidence and nature of adverse drug events in paediatric intensive care units: A prospective multicentre study

Autor: Anwar A. Alghamdi, Richard N. Keers, Adam Sutherland, Mark Hann, Jennifer Gray, Graham Mason, Rhian E. Isaac, Darren M. Ashcroft

Publikováno v: Alghamdi, A A, Keers, R N, Sutherland, A, Hann, M, Gray, J, Mason, G, Isaac, R E & Ashcroft, D M 2022, ' Incidence and nature of adverse drug events in paediatric intensive care units: A prospective multicentre study ', British Journal of Clinical Pharmacology, vol. 88, no. 5, pp. 2213-2222 . https://doi.org/10.1111/bcp.15150

AimsThe aim of this study was to assess the incidence, nature, preventability and severity of adverse drug events (ADEs) across three paediatric intensive care units (PICUs) in England.MethodsA prospective observational cohort study was conducted acr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45437b135d9e1e663ebbd27de0677b0
https://doi.org/10.1111/bcp.15150

Tracheal Bronchus: A Rare Etiology of Recurrent Pneumonia in Children

Autor: Saif A Alqahtani, Anwar M Alghamdi, Rawan A Babader, Doaa A Aljehani, Razan K Alsultan, Rawiah Y Mushari, Maha Y Alyahya, Hawra I Alajwad, Ahmad A Alibrahim, Egbal B Altukruni, Reem N Alhasani, Arwa T Mandurah, Yara A Halabi, Batool J Alghamdi, Faisal Al-Hawaj

Publikováno v: Cureus

Recurrent infections are a common cause for seeking medical care and they result in significant parental anxiety and concerns. Although immunodeficiency disorders are an important underlying cause of recurrent infections, the majority of children wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f29c457b8237654e44fd3c9c0263d9c
http://europepmc.org/articles/PMC8743048