Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anuvrat Sircar"'
Autor:
Anuvrat Sircar, Sayan Mullick Chowdhury, Amber Hart, William Connor Bell, Satishkumar Singh, Lalit Sehgal, Narendranath Epperla
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 904 (2020)
Lymphoma, a group of widely prevalent hematological malignancies of lymphocyte origin, has become the focus of significant clinical research due to their high propensity for refractory/relapsed (R/R) disease, leading to poor prognostic outcomes. The
Externí odkaz:
https://doaj.org/article/a52a3d08737b4da69bc898e9a6791ee4
Autor:
Chinmayee Goda, Sofia Kolovich, Alexander Rudich, Malith Karunasiri, Rohan Kulkarni, Girish Rajgolikar, Lotus Neidemire-Colley, Satishkumar Singh, Anuvrat Sircar, Parvathi Ranganathan, Ramiro Garzon, Lalit Sehgal, Adrienne M. Dorrance
Publikováno v:
Experimental Hematology.
Autor:
Satishkumar Singh, Fouad Choueiry, Anuvrat Sircar, Narendranath Epperla, Jiangjiang Zhu, Lalit Sehgal
Publikováno v:
Cancer Research. 83:3689-3689
DLBCL is the most common B cell malignancy in adults accounting for 30-40% of non-Hodgkin lymphoma. Only 60% of these cases are curable, with activated B cell DLBCL (ABC-DLBCL) having inferior outcomes than the germinal center (GCB) DLBCL. The use of
Publikováno v:
Cancer Research. 83:1422-1422
Cell cycle dysregulation and significant enrichment of E2F1 target genes are hallmarks of MCL, and the inability to directly target E2F1-dependent processes is a clinical hindrance. Despite several treatment options, mantle cell lymphoma is associate
Autor:
Georgios I. Laliotis, Elizabeth M. Muhowski, Fazal Shirazi, Ondrej Havranek, Satishkumar Singh, Lalit Sehgal, Tereza Chrbolkova, Amber Hart, Kristyna Kupcova, Tamer Khashab, Jiangjiang Zhu, Anuvrat Sircar, Jennifer A. Woyach, Lapo Alinari, Sayan Mullick Chowdhury, Robert A. Baiocchi, Felipe Samaniego, Neeraj Jain, Ram Kumar Singh, Philip N. Tsichlis
Publikováno v:
Blood Adv
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma; 40% of patients relapse after a complete response or are refractory to therapy. To survive, the activated B-cell (ABC) subtype of DLBCL relies upon B-cell recep
Autor:
Evangelia Chavdoula, Vollter Anastas, Alessandro La Ferlita, Julian Aldana, Anuvrat Sircar, Michael A. Freitas, Lalit Sehgal, Philip N. Tsichlis
Publikováno v:
Cancer Research. 82:3019-3019
Epigenetic and metabolic alterations in cancer cells are intertwined. The concentration of metabolites can influence the activity of chromatin modifiers, which in turn can act as metabolic sensors that translate changes in cellular metabolism to tran
Autor:
JoBeth Helmig-Mason, Amber Hart, Robert A. Baiocchi, Shiqi Zhang, Lalit Sehgal, Xiaowei Sun, Fouad Choueiry, Evangelia Chavdoula, Georgios I. Laliotis, Jiangjiang Zhu, Anuvrat Sircar, Satishkumar Singh, Philip N. Tsichlis, Lapo Alinari, Narendranath Epperla
Publikováno v:
Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2146, p 2146 (2021)
Volume 13
Issue 9
Cancers, Vol 13, Iss 2146, p 2146 (2021)
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL). B-cell NHLs rely on Bruton’s tyrosine kinase (BTK) mediated B-cell receptor signaling for survival and disease progression. However, they are often resistant to BT
Autor:
Epperla Narendranath, Jiangjiang Zhu, Anuvrat Sircar, Shiqi Zhang, Lapo Alinari, Lalit Sehgal, Hart Amber, Xiaowei Sun, Robert A. Baiocchi, Satishkumar Singh, Fouad Choueiry
BackgroundDiffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL). B-cell NHLs rely on Bruton’s tyrosine kinase (BTK) mediated B-cell receptor signaling for survival and disease progression. However, they are often resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8380199c5dd4117a138567706df6e10
https://doi.org/10.1101/2021.01.07.425721
https://doi.org/10.1101/2021.01.07.425721
Autor:
Sayan Mullick Chowdhury, Amber Hart, Bhawana George, Lalit Sehgal, Neeraj Jain, Satish Kumar Singh, Mukesh Mamgain, Naveen Kumar Singhal, Anuvrat Sircar, Uttam Kumar Nath
Publikováno v:
Cancers, Vol 12, Iss 1328, p 1328 (2020)
Cancers
Cancers
Chronic activation of B-cell receptor (BCR) signaling via Bruton tyrosine kinase (BTK) is largely considered to be one of the primary mechanisms driving disease progression in B–Cell lymphomas. Although the BTK-targeting agent ibrutinib has shown p
Autor:
Lalit Sehgal, Sayan Mullick Chowdhury, William Connor Bell, Anuvrat Sircar, Narendranath Epperla, Amber Hart, Satishkumar Singh
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 904 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Lymphoma, a group of widely prevalent hematological malignancies of lymphocyte origin, has become the focus of significant clinical research due to their high propensity for refractory/relapsed (R/R) disease, leading to poor prognostic outcomes. The