Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Anusyah Rathakrishnan"'
Autor:
Anusyah Rathakrishnan, Ana L. Reis, Vlad Petrovan, Lynnette C. Goatley, Katy Moffat, Yuan Lui, Mai T. Vuong, Shinji Ikemizu, Simon J. Davis, Linda K. Dixon
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
African swine fever virus is a complex DNA virus that causes high fatality in pigs and wild boar and has a great socio-economic impact. An attenuated genotype II strain was constructed by replacing the gene for wildtype CD2v protein with versions in
Externí odkaz:
https://doaj.org/article/f20f1127e5e54fceacc00ca1de7a56ff
Publikováno v:
Viruses, Vol 13, Iss 8, p 1473 (2021)
African swine fever virus causes a frequently fatal disease of domestic pigs and wild boar that has a high economic impact across 3 continents. The large double-stranded DNA genome codes for approximately 160 proteins. Many of these have unknown func
Externí odkaz:
https://doaj.org/article/c0e908cff86f4940b563721fabb46532
Publikováno v:
Proceedings, Vol 50, Iss 1, p 57 (2020)
African Swine Fever Virus (ASFV) is a haemorrhagic infection of swine, which routinelydisplays 100% lethality. [...]
Externí odkaz:
https://doaj.org/article/16de55665c444064a3f76fa119a46ebc
Publikováno v:
Viruses, Vol 12, Iss 6, p 615 (2020)
African swine fever (ASF) is a devastating disease in pigs, with no vaccines for control. The genetic manipulation of African swine fever virus (ASFV) is often tedious and time consuming. Here, we describe a method to manipulate the virus genome to p
Externí odkaz:
https://doaj.org/article/590dee06f31648be9e869d0ffcba9e7e
Autor:
Ana Luisa Reis, Lynnette C. Goatley, Tamara Jabbar, Elisabeth Lopez, Anusyah Rathakrishnan, Linda K. Dixon
Publikováno v:
Vaccines, Vol 8, Iss 2, p 262 (2020)
Live attenuated vaccines are considered to be the fastest route to the development of a safe and efficacious African swine fever (ASF) vaccine. Infection with the naturally attenuated OURT88/3 strain induces protection against challenge with virulent
Externí odkaz:
https://doaj.org/article/26f2780a2185474193912c0874dabe8b
Autor:
Anusyah Rathakrishnan, Benjamin Klekamp, Seok Mui Wang, Thamil Vaani Komarasamy, Santha Kumari Natkunam, Jameela Sathar, Azliyati Azizan, Aurora Sanchez-Anguiano, Rishya Manikam, Shamala Devi Sekaran
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92021 (2014)
With its elusive pathogenesis, dengue imposes serious healthcare, economic and social burden on endemic countries. This study describes the clinical and immunological parameters of a dengue cohort in a Malaysian city, the first according to the WHO 2
Externí odkaz:
https://doaj.org/article/b6a32a43b9fc40fbb4ebfa60ba4e6a27
Autor:
Adeline S L Yeo, Nur Atiqah Azhar, Wanyi Yeow, C Conover Talbot, Mohammad Asif Khan, Esaki M Shankar, Anusyah Rathakrishnan, Azliyati Azizan, Seok Mui Wang, Siew Kim Lee, Mun Yik Fong, Rishya Manikam, Shamala Devi Sekaran
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92240 (2014)
OBJECTIVES: Dengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, asymptomatic dengu
Externí odkaz:
https://doaj.org/article/37bad3258ac04231be8a1bb1aaf0d9de
Autor:
Anusyah Rathakrishnan, Seok Mui Wang, Yongli Hu, Asif M Khan, Sasheela Ponnampalavanar, Lucy Chai See Lum, Rishya Manikam, Shamala Devi Sekaran
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52215 (2012)
BACKGROUND: Dengue is an important medical problem, with symptoms ranging from mild dengue fever to severe forms of the disease, where vascular leakage leads to hypovolemic shock. Cytokines have been implicated to play a role in the progression of se
Externí odkaz:
https://doaj.org/article/49806cd1ac0d47bb926bc55ac1dd7c32
Autor:
Ana Luisa Reis, Anusyah Rathakrishnan, Leah V. Goulding, Claire Barber, Lynnette C. Goatley, Linda K. Dixon
African swine fever virus encodes proteins that inhibit apoptosis including one member of the BCL-2 family, A179L. Deletion of the A179L gene from the virulent genotype I isolate Benin 97/1 compared to Benin 97/1 expressing A179L or mock-infected mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19088f56a4a8a0d884211d8650894ac4
https://doi.org/10.1101/2023.04.27.538639
https://doi.org/10.1101/2023.04.27.538639
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2503
Genetic manipulation of ASFV has been increasingly used not only for the development of live attenuated vaccines but also as an indispensable tool to further our understanding of the virus-host interactions. Here we present methods for isolation of p