Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anusmita Sahoo"'
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Nanda Kishore Routhu, Narayanaiah Cheedarla, Venkata Satish Bollimpelli, Sailaja Gangadhara, Venkata Viswanadh Edara, Lilin Lai, Anusmita Sahoo, Ayalnesh Shiferaw, Tiffany M. Styles, Katharine Floyd, Stephanie Fischinger, Caroline Atyeo, Sally A. Shin, Sanjeev Gumber, Shannon Kirejczyk, Kenneth H. Dinnon, Pei-Yong Shi, Vineet D. Menachery, Mark Tomai, Christopher B. Fox, Galit Alter, Thomas H. Vanderford, Lisa Gralinski, Mehul S. Suthar, Rama Rao Amara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Efficient vaccines for SARS-CoV-2 are needed. Here, the authors show that a trimeric form of the receptor-binding domain of SARS-CoV-2 spike adjuvanted with alum-3M-052 protects non-human primates from disease and inhibits infection.
Externí odkaz:
https://doaj.org/article/eb5e727593c442beadc6bb289092f047
Autor:
Tiffany M. Styles, Sailaja Gangadhara, Pradeep B. J. Reddy, Anusmita Sahoo, Ayalensh Shiferaw, Sarah Welbourn, Pamela A. Kozlowski, Cynthia A. Derdeyn, Vijayakumar Velu, Rama Rao Amara
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stabilized HIV envelope (Env) trimeric protein immunogens have been shown to induce strong autologous neutralizing antibody response. However, there is limited data on the immunogenicity and efficacy of stabilized Env expressed by a viral vector-base
Externí odkaz:
https://doaj.org/article/81f9a87b6bff43e3a8a1399b0ad63c82
Publikováno v:
eLife, Vol 4 (2015)
Identification of residue-residue contacts from primary sequence can be used to guide protein structure prediction. Using Escherichia coli CcdB as the test case, we describe an experimental method termed saturation-suppressor mutagenesis to acquire r
Externí odkaz:
https://doaj.org/article/bc1a2869bcb3488c9a44d3b864ecb6bd
Autor:
Robert Sonowal, Alyson I. Swimm, Francesca Cingolani, Noyonika Parulekar, Tesia L. Cleverley, Anusmita Sahoo, Ayush Ranawade, Debalina Chaudhuri, Edward S. Mocarski, Heather Koehler, Karolina Nitsche, Sam Mesiano, Daniel Kalman
Publikováno v:
Science Advances. 9
During aging, environmental stressors and mutations along with reduced DNA repair cause germ cell aneuploidy and genome instability, which limits fertility and embryo development. Benevolent commensal microbiota and dietary plants secrete indoles, wh
Autor:
Anusmita Sahoo, Andrew T. Jones, Narayanaiah Cheedarla, Sailaja Gangadhara, Vicky Roy, Tiffany M. Styles, Ayalnesh Shiferaw, Korey L. Walter, LaTonya D. Williams, Xiaoying Shen, Gabriel Ozorowski, Wen-Hsin Lee, Samantha Burton, Lasanajak Yi, Xuezheng Song, Zhaohui S. Qin, Cynthia A. Derdeyn, Andrew B. Ward, John D. Clements, Raghavan Varadarajan, Georgia D. Tomaras, Pamela A. Kozlowski, Galit Alter, Rama Rao Amara
Publikováno v:
Sci Immunol
The rising global HIV-1 burden urgently requires vaccines capable of providing heterologous protection. Here, we developed a clade C HIV-1 vaccine consisting of priming with modified vaccinia Ankara (MVA) and boosting with cyclically permuted trimeri
Autor:
Celia C. LaBranche, Anusmita Sahoo, Edgar A. Hodge, Styles Tt, Narayanaiah Cheedarla, David C. Montefiori, Ayalnesh Shiferaw, Wen-Hsin Lee, Kelly K. Lee, Rama Rao Amara, Georgia D. Tomaras, Andrew B. Ward, Darrell J. Irvine, Gabriel Ozorowski, Xiaoying Shen
SummaryHIV-1 clade C envelope immunogens that elicit both neutralizing and non-neutralizing V1V2-scaffold specific antibodies (protective correlates from RV144 human trial) are urgently needed due to the prevalence of this clade in the most impacted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a4c7943c0244ea7043bb1837db89b81
https://doi.org/10.1101/2021.06.15.447100
https://doi.org/10.1101/2021.06.15.447100
Autor:
Mehul S. Suthar, Sailaja Gangadhara, Shannon Kirejczyk, Vineet D. Menachery, Narayanaiah Cheedarla, Venkata Viswanadh Edara, Sally Shin, Venkata S. Bollimpelli, Stephanie Fischinger, Katharine Floyd, Caroline Atyeo, Anusmita Sahoo, Pei Yong Shi, Kenneth H. Dinnon, Rama Rao Amara, Christopher B. Fox, Thomas H. Vanderford, Lilin Lai, Galit Alter, Lisa E. Gralinski, Tiffany M. Styles, Sanjeev Gumber, Ayalnesh Shiferaw, Mark A. Tomai, Nanda Kishore Routhu
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
There is a great need for the development of vaccines that induce potent and long-lasting protective immunity against SARS-CoV-2. Multimeric display of the antigen combined with potent adjuvant can enhance the potency and longevity of the antibody re
Autor:
Shelly Wang, Steven E. Bosinger, Joyce Cohen, Sally Shin, Pei Yong Shi, Stephanie Fischinger, Fawn Connor-Stroud, Amit A. Upadhyay, Sailaja Gangadhara, Katharine Floyd, Sanjeev Gumber, Narayanaiah Cheedarla, Jennifer S. Wood, Mehul S. Suthar, Rama Rao Amara, Anusmita Sahoo, Ayalnesh Shiferaw, Nanda Kishore Routhu, Rachelle L. Stammen, Venkata Viswanadh Edara, David C. Montefiori, Vineet D. Menachery, Venkata S. Bollimpelli, Shannon Kirejczyk, Caroline Atyeo, Galit Alter, Thomas H. Vanderford, Lilin Lai, Sherrie Jean, Sheikh Abdul Rahman, Kathryn L. Pellegrini, Arun K. Boddapati
Publikováno v:
Immunity
A combination of vaccination approaches will likely be necessary to fully control the SARS-CoV-2 pandemic. Here, we show that modified vaccinia Ankara (MVA) vectors expressing membrane anchored pre-fusion stabilized spike (MVA/S), but not secreted S1
Autor:
Anusmita Sahoo, Edgar A. Hodge, Celia C. LaBranche, Tiffany M. Styles, Xiaoying Shen, Narayanaiah Cheedarla, Ayalnesh Shiferaw, Gabriel Ozorowski, Wen-Hsin Lee, Andrew B. Ward, Georgia D. Tomaras, David C. Montefiori, Darrell J. Irvine, Kelly K. Lee, Rama Rao Amara
Publikováno v:
Cell Reports. 38:110436
HIV-1 clade C envelope immunogens that elicit both neutralizing and non-neutralizing V1V2-scaffold-specific antibodies (protective correlates from RV144 human trial) are urgently needed due to the prevalence of this clade in the most impacted regions