Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anusha Chaparala"'
Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2
Autor:
Anusha Chaparala, Hossam Tashkandi, Alexander A. Chumanevich, Erin E. Witalison, Anthony Windust, Taixing Cui, Mitzi Nagarkatti, Prakash Nagarkatti, Lorne J. Hofseth
Publikováno v:
Nutrients, Vol 12, Iss 6, p 1850 (2020)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects millions of people worldwide and increases the risk of colorectal cancer (CRC) development. We have previously shown that American ginseng (AG) can treat colitis and prevent
Externí odkaz:
https://doaj.org/article/53dd12b7fd0340d8846c937c125e563f
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Supplemental tables include gene lists related to Figure 5, additional experimental data related to Figure S3I, and primers sequence. Table S1. Numbers of spheroids were counted for each cell dilution; Table S2. List of 20 genes that exhibit a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4db76b7ecfc0ad59596eb28359bec1c
https://doi.org/10.1158/0008-5472.22426420.v1
https://doi.org/10.1158/0008-5472.22426420.v1
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
N6-Methyladenosine (m6A) is the most abundant modification of mammalian mRNAs. RNA methylation fine tunes RNA stability and translation, altering cell fate. The fat mass- and obesity-associated protein (FTO) is an m6A demethylase with oncogenic prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fa8ff554637f215faedce96bb13452
https://doi.org/10.1158/0008-5472.c.6512335
https://doi.org/10.1158/0008-5472.c.6512335
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Additional experimental results supporting the main figures are included. Figure S1. Expression of key RNA methylation regulators in OC; Figure S2. Flow cytometry analysis for ALDH and CD133 in single cell suspensions derived from human ovarian tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58586bffed12f0249ddde8730d686066
https://doi.org/10.1158/0008-5472.22426426
https://doi.org/10.1158/0008-5472.22426426
Autor:
Daniela Matei, Ramana V. Davuluri, Jianjun Chen, Edward J. Tanner, Anusha Chaparala, Yanrong Ji, Horacio Cardenas, Guangyuan Zhao, Manoj Kandpal, Yinu Wang, Hao Huang
Detailed information regarding materials and methods are included in this file.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789fb8c2e51f444d790d3c503ca8da45
https://doi.org/10.1158/0008-5472.22426423.v1
https://doi.org/10.1158/0008-5472.22426423.v1
Autor:
Hao Huang, Yanrong Ji, Guangyuan Zhao, Jianjun Chen, Edward J. Tanner, Manoj Kandpal, Anusha Chaparala, Yinu Wang, Ramana V. Davuluri, Daniela Matei, Horacio Cardenas
Publikováno v:
Cancer Research. 80:3200-3214
N6-Methyladenosine (m6A) is the most abundant modification of mammalian mRNAs. RNA methylation fine tunes RNA stability and translation, altering cell fate. The fat mass- and obesity-associated protein (FTO) is an m6A demethylase with oncogenic prope
Autor:
Deepak Poudyal, Prakash S. Nagarkatti, Olivia Hardy, Erin E. Witalison, Ivy Nguyen, Jenna L. Hofseth, Lorne J. Hofseth, Anthony Windust, Alexander A. Chumanevich, E. A. Murphy, Hossam Tashkandi, Mitzi Nagarkatti, Anusha Chaparala, Douglas L. Pittman, Michael D. Wyatt
Publikováno v:
Oncotarget
Ulcerative colitis has a significant impact on the quality of life for the patients, and can substantially increase the risk of colon cancer in patients suffering long-term. Conventional treatments provide only modest relief paired with a high risk o
Autor:
Hossam Tashkandi, Anusha Chaparala, Sean Peng, Mitzi Nagarkatti, Prakash Nagarkatti, Alexander, A. Chumanevich, Lorne J. Hofseth
Publikováno v:
Journal of cancer science and clinical therapeutics
The purpose of our study is to explore the pharmacokinetic parameters of panaxynol (PA) and understand its potential and dosage used in pre-clinical animal models. For in vitro analysis, 5 μM of PA was added to liver microsomes of mouse and human sp
Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2
Autor:
Mitzi Nagarkatti, Alexander A. Chumanevich, Hossam Tashkandi, Lorne J. Hofseth, Taixing Cui, Prakash S. Nagarkatti, Erin E. Witalison, Anthony Windust, Anusha Chaparala
Publikováno v:
Nutrients
Volume 12
Issue 6
Nutrients, Vol 12, Iss 1850, p 1850 (2020)
Volume 12
Issue 6
Nutrients, Vol 12, Iss 1850, p 1850 (2020)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects millions of people worldwide and increases the risk of colorectal cancer (CRC) development. We have previously shown that American ginseng (AG) can treat colitis and prevent
Autor:
Hao, Huang, Yinu, Wang, Manoj, Kandpal, Guangyuan, Zhao, Horacio, Cardenas, Yanrong, Ji, Anusha, Chaparala, Edward J, Tanner, Jianjun, Chen, Ramana V, Davuluri, Daniela, Matei
Publikováno v:
Cancer Res
N(6)-Methyladenosine (m(6)A) is the most abundant modification of mammalian messenger RNAs (mRNA). RNA methylation fine tunes RNA stability and translation, altering cell fate. The fat mass- and obesity-associated protein (FTO) is an m(6)A demethylas