Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anusha Balla"'
Autor:
Anusha Balla, Bao Tran, Annika Valtari, Philipp Steven, Camilla Scarpellini, Koen Augustyns, Arto Urtti, Kati-Sisko Vellonen, Marika Ruponen
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 118 (2022)
Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a novel ferroptosis inhibitor, UAMC-3203 (10 nM–50 µM), in corneal epithelial wound healing in
Externí odkaz:
https://doaj.org/article/d1136f4a281c4e77b6f05239a3ddcb2a
Autor:
Anusha Balla, Yoo-Seong Jeong, Hyo-Jung Kim, Yun-Jong Lee, Suk-Jae Chung, Yoon-Jee Chae, Han-Joo Maeng
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1133 (2021)
In this study, possible changes in the expression of rat organic cationic transporters (rOCTs) and rat multidrug and toxin extrusion proteins (rMATEs) following treatment with 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) were investigated. Rats received
Externí odkaz:
https://doaj.org/article/7a907a36f5b24c6f8f30eb727a7472ad
Autor:
Anusha Balla, Seppo Auriola, Angus C. Grey, Nicholas J. Demarais, Annika Valtari, Emma M. Heikkinen, Elisa Toropainen, Arto Urtti, Kati-Sisko Vellonen, Marika Ruponen
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 658 (2021)
Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood. We investigated partitioning of seven beta-blocking drugs in corneal epithelium, corneal strom
Externí odkaz:
https://doaj.org/article/162eda48723a475a9751d6954d92caef
Publikováno v:
Pharmaceutics, Vol 11, Iss 3, p 108 (2019)
Previous observations demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) resulting in the increased systemic exposure and the decrease of urinary excretion. Despi
Externí odkaz:
https://doaj.org/article/ea8dccf6141a42638c838d144243b3b5
Publikováno v:
Pharmaceutics, Vol 10, Iss 2, p 41 (2018)
A simple, sensitive, and reliable reversed-phase, Ultra-High-Pressure Liquid Chromatography (UHPLC) coupled with a Diode Array Detector (DAD) method for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamid
Externí odkaz:
https://doaj.org/article/86328fc7d7cd49ed98fbb93bbcd23550
Autor:
Anam Hammid, John K. Fallon, Toni Lassila, Paula Vieiro, Anusha Balla, Francisco Gonzalez, Arto Urtti, Philip C. Smith, Ari Tolonen, Paavo Honkakoski
Publikováno v:
Drug Metabolism and Disposition. 50:1483-1492
As a multitissue organ, the eye possesses unique anatomy and physiology, including differential expression of drug-metabolizing enzymes. Several hydrolytic enzymes that play a major role in drug metabolism and bioactivation of prodrugs have been dete
Autor:
Anusha Balla, Marika Ruponen, Annika Valtari, Elisa Toropainen, Marjo Tuomainen, Carmen Alvarez-Lorenzo, Eva M. del Amo, Arto Urtti, Kati-Sisko Vellonen
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
Rapid precorneal loss of topically applied eye drops limits ocular drug absorption. Controlling release and precorneal residence properties of topical formulations may improve ocular drug bioavailability and duration of action. In this study, we eval
Autor:
Ruponen, Anusha Balla, Bao Tran, Annika Valtari, Philipp Steven, Camilla Scarpellini, Koen Augustyns, Arto Urtti, Kati-Sisko Vellonen, Marika
Publikováno v:
Pharmaceutics; Volume 15; Issue 1; Pages: 118
Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a novel ferroptosis inhibitor, UAMC-3203 (10 nM–50 µM), in corneal epithelial wound healing in
Autor:
Hyo Jung Kim, In-Soo Yoon, Trang Nguyen Kieu Doan, Yunjong Lee, Dang-Khoa Vo, Anusha Balla, Han-Joo Maeng
Publikováno v:
Pharmaceutics
Volume 12
Issue 11
Volume 12
Issue 11
The compound 1&alpha
25-Dihydroxyvitamin D3 (1,25(OH)2D3) is the active form of vitamin D3 and a representative ligand of the vitamin D receptor (VDR). Previous studies have described the impacts of 1,25(OH)2D3 on a small number of cytochrome P4
25-Dihydroxyvitamin D3 (1,25(OH)2D3) is the active form of vitamin D3 and a representative ligand of the vitamin D receptor (VDR). Previous studies have described the impacts of 1,25(OH)2D3 on a small number of cytochrome P4
Autor:
Yunjong Lee, Han-Joo Maeng, Anusha Balla, Suk-Jae Chung, Yoo-Seong Jeong, Yoon-Jee Chae, Hyo Jung Kim
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1133, p 1133 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1133, p 1133 (2021)
In this study, possible changes in the expression of rat organic cationic transporters (rOCTs) and rat multidrug and toxin extrusion proteins (rMATEs) following treatment with 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) were investigated. Rats received