Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anurag Singh Sikarwar"'
Publikováno v:
The Journal of membrane biology. 252(4-5)
G protein-coupled receptors (GPCRs) play a pivotal role in the adaptive responses to cellular stresses such as hypoxia. In addition to influencing cellular gene expression profiles, hypoxic microenvironments can perturb membrane protein localization,
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1947
G protein-coupled receptors (GPCR) are crucial transducers of extracellular signals into changes in vascular tone. Vasoactive GPCR stimulation in the pulmonary circuit may be elicited by agonists released in acute tissue hypoxia or inflammation, as w
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991204
G protein-coupled receptors (GPCR) are crucial transducers of extracellular signals into changes in vascular tone. Vasoactive GPCR stimulation in the pulmonary circuit may be elicited by agonists released in acute tissue hypoxia or inflammation, as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eadc156df298ebec0ea7018ef5f2d8d
https://doi.org/10.1007/978-1-4939-9121-1_23
https://doi.org/10.1007/978-1-4939-9121-1_23
Autor:
Martha Hinton, Shyamala Dakshinamurti, Anurag Singh Sikarwar, Kallivalappil Thomas Santhosh, Mariel Talabis, Premnath Dhanaraj, Prashen Chelikani
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 315(6)
Persistent pulmonary hypertension of the newborn (PPHN) features hypoxemia, pulmonary vasoconstriction, and impaired cardiac inotropy. We previously reported low basal and stimulated cAMP in hypoxic pulmonary artery smooth muscle cells (PASMCs). We n
Autor:
Yasser Elsayed, Reem Amer, Marjory Ruth Graham, Anurag Singh Sikarwar, Martha Hinton, Shyamala Dakshinamurti
Publikováno v:
Pediatric pulmonology. 54(3)
Background Persistent pulmonary hypertension of the newborn (PPHN) is due to a failure of pulmonary vascular relaxation. Vasopressin, a systemic vasoconstrictor acting on smooth muscle AVPR1a receptors, is used in treatment of PPHN. We sought to dete
Autor:
Raja, Chakraborty, Anurag Singh, Sikarwar, Martha, Hinton, Shyamala, Dakshinamurti, Prashen, Chelikani
Publikováno v:
Methods in cell biology. 142
G protein-coupled receptors (GPCRs) signal in response to various external stimuli including stress. GPCR signaling has been shown to play a critical role in the adaptation of cell response to limited oxygen supply. Hypoxia has been implicated in car
Autor:
Shyamala Dakshinamurti, Martha Hinton, Prashen Chelikani, Anurag Singh Sikarwar, Raja Chakraborty
G protein-coupled receptors (GPCRs) signal in response to various external stimuli including stress. GPCR signaling has been shown to play a critical role in the adaptation of cell response to limited oxygen supply. Hypoxia has been implicated in car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35645053f03646dba2b8c5801e2c5069
https://doi.org/10.1016/bs.mcb.2017.07.005
https://doi.org/10.1016/bs.mcb.2017.07.005
Autor:
K.T. Santhosh, Martha Hinton, Anurag Singh Sikarwar, Prashen Chelikani, Shyamala Dakshinamurti
Publikováno v:
British Journal of Pharmacology. 171:676-687
Background and Purpose Dysregulation of the thromboxane A2 (TP) receptor, resulting in agonist hypersensitivity and hyper-responsiveness, contributes to exaggerated vasoconstriction in the hypoxic pulmonary artery in neonatal persistent pulmonary hyp
Autor:
Kangmin Duan, Rajinder P. Bhullar, Shyamala Dakshinamurti, Anurag Singh Sikarwar, Nisha Singh, Appalaraju Jaggupilli, Jasbir D. Upadhyaya, Makoto Arakawa, Prashen Chelikani
Publikováno v:
Molecular and cellular biochemistry. 426(1-2)
The 25 bitter taste receptors (T2Rs) in humans perform a chemosensory function. However, very little is known about the level of expression of these receptors in different tissues. In this study, using nCounter gene expression we analyzed the express
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 307(11)
In hypoxic pulmonary arterial (PA) myocytes, challenge with thromboxane mimetic U46619 induces marked actin polymerization and contraction, phenotypic features of persistent pulmonary hypertension of the newborn (PPHN). Rho GTPases regulate the actin