Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anuradha Cingeetham"'
Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India
Autor:
Manjula Gorre, Nageswara Rao Dunna, Sailaja Kagita, Santhoshirani Nanchari, Sarika Jarjapu, Sugunakar Vuree, Phanni Bhushann Meka, Anuradha Cingeetham, Raghunadharao Digumarti, Sandhya Annamaneni, Vishnupriya Satti, Prajitha Edathara Mohandas
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 17:815-821
Background Development of chronic myeloid leukemia (CML) involves formation of double strand breaks (DSBs) which are initially sensed by the ataxia telangiectasia mutated (ATM) signal kinase to induce a DNA damage response (DDR). Mutations or single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45aad89b1508cd2e113f074f84689d4c
https://doi.org/10.7314/apjcp.2016.17.2.815
https://doi.org/10.7314/apjcp.2016.17.2.815
Autor:
Satti, Bhushann Meka P, Srinivasulu Mukta, Sandhya Annamaneni, Triveni B, Sarika Jarjapu, Sandeep Kumar Vishwakarma, Nanchari, Anuradha Cingeetham
Publikováno v:
Tumor Biology. 37:6905-6912
BCL2 (B-cell leukemia/lymphoma 2) gene functions as antiapoptotic regulatory element and known to be associated with tumorigenesis. The SNP-938 (C>A) (rs2279115), located in the inhibitory P2 promoter of the BCL2 gene, influences differential binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6377ba835633c0e238a4023a7cd63908
https://doi.org/10.1007/s13277-015-4554-0
https://doi.org/10.1007/s13277-015-4554-0
Autor:
Vishnupriya Satti, Anuradha Cingeetham, Sailaja Kagita, Raghunadharao Digumarti, Manjula Gorre, Prajitha Mohandas Edathara, Sandhya Annamaneni
Publikováno v:
Gene: X, Vol 1, Iss, Pp-(2019)
Gene: X
Gene: X
Introduction Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder, characterized by the overproduction of myeloid cells in all stages of maturation. It is usually defined by three sequential stages (Chronic, Accelerated and Blast-crisis) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765fc565e9da7cc56e2661417d70b95b
https://pubmed.ncbi.nlm.nih.gov/34530993
https://pubmed.ncbi.nlm.nih.gov/34530993
Autor:
Santhoshi Rani Nanchari, Sugunakar Vuree, Anuradha Cingeetham, Manjula Gorre, Prajitha Mohandas Edathara, Vishnupriya Satti, Sandhya Annamaneni, Raghunadha Rao Digumarthi, Sailaja Kagita, Phanni Bhushann Meka
Publikováno v:
Tumor Biology. 37:5475-5484
Chronic myeloid leukemia (CML) is a monoclonal myeloproliferative disorder of hematopoietic stem cells (HSCs), characterized by reciprocal translocation, leading to the formation of BCR-ABL oncogene with constitutive tyrosine kinase (TK) activity. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630405a8843e6925bde723ea96c0906e
https://doi.org/10.1007/s13277-015-4295-0
https://doi.org/10.1007/s13277-015-4295-0
Autor:
Manjula Gorre, Triveni B, Sarika Jarjapu, Santhoshi Rani Nanchari, Srinivasulu Mukta, Sandhya Annamaneni, Anuradha Cingeetham, Prajitha Mohandas Edathara, Vishnupriya Satti, Nageswara Rao Dunna, Sandeep Kumar Vishwakarma, Phanni Bhushann Meka, Sugunakar Vuree
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 16:4965-4969
LCN2 (Lipocalin 2) is a 25 KD secreted acute phase protein, reported to be a novel regulator of angiogenesis in breast cancer. Up regulation of LCN2 had been observed in multiple cancers including breast cancer, pancreatic cancer and ovarian cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5499879c138ff49f50a1715c5714ef
https://doi.org/10.7314/apjcp.2015.16.12.4965
https://doi.org/10.7314/apjcp.2015.16.12.4965
Autor:
Manjula Gorre, Sudha Sinha, Prajitha Mohandas Edathara, Sugunakar Vuree, Anuradha Cingeetham, Nageswara Rao Dunna, Sandhya Annamaneni, Santhoshi Rani Nanchari, Vishnupriya Satti, Raghunadharao Digumarthi, Phannibhushann Meka
Publikováno v:
Tumor Biology. 36:7967-7976
B-cell lymphoma 2 (BCL2) and BCL2-associated X protein (BAX) proteins are anti-apoptotic and pro-apoptotic determinants of mitochondrial-mediated apoptosis, and their relative expression determines the cell fate. The promoter polymorphisms in these g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431b5d6d80b16be1fe47d8360defbe17
https://doi.org/10.1007/s13277-015-3457-4
https://doi.org/10.1007/s13277-015-3457-4
Autor:
Raghunadharao Digumarthi, Manjula Gorre, Vishnupriya Satti, Santhoshi Rani Nanchari, Anuradha Cingeetham, Sandhya Annamaneni, Surekha Damineni, Sarika Jarjapu, Nageshwarao Tipirisetti, Phanni Bhushann Meka
Publikováno v:
Tumor Biology. 36:3215-3220
Hypoxia-inducible factor 1α (HIF-1α) is an important transcription factor that regulates different cellular responses to hypoxia. HIF-1α is rapidly degraded by von Hippel-Lindau (VHL) protein under normoxic conditions and stabilized under hypoxia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167b354b46e7f182acd0e694ed941d40
https://doi.org/10.1007/s13277-014-2949-y
https://doi.org/10.1007/s13277-014-2949-y
Autor:
Raghunadharao Digumarthi, Manjula Gorre, Sugunakar Vuree, Vishnupriya Satti, Dunna Nageswara Rao, Anuradha Cingeetham, Sadashivudu Gundeti, Sudha Sinha
Publikováno v:
Blood. 134:5076-5076
Purpose of the study: Deregulated DNA repair is one of the hallmarks of cancers including Acute Myeloid Leukemia (AML), as it results in genomic instability. ATM gene functions as a sensor, activates cascade of events leading to stimulation of multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe7d33a8bac6307aca37398f2d561ed3
https://doi.org/10.1182/blood-2019-127860
https://doi.org/10.1182/blood-2019-127860
Autor:
Anuradha Cingeetham, Raghunadharao Digumarti, Manjula Gorre, Sangeeta Jiwatani, Sudha Sinha, Vishnupriya Satti, Sandhya Annamaneni, Sailaja Kagita, Phanni Bhushann Meka, Nageswara Rao Dunna, Sugunakar Vuree
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 16(7)
The human homologue of the mouse double minute 2 (MDM2) gene is a negative regulator of Tp53. MDM2-309TG a functional promoter polymorphism was found to be associated with overexpression thereby attenuation of Tp53 stress response and increased cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bd3498e03ed03324d64fb4827befc2
https://pubmed.ncbi.nlm.nih.gov/25854351
https://pubmed.ncbi.nlm.nih.gov/25854351
Autor:
Nageshwarao Tipirisetti, Surekha Rani Hanumanth, Raghunadha Rao Digumarthi, Surekha Damineni, Chiranjeevi Padala, Sandhya Annamaneni, Vishnupriya Satti, Phannibhushann Meka, Anuradha Cingeetham, Santhoshi Rani Nanchari
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 36(2)
Rrp1B (ribosomal RNA processing1 homolog B) is a novel candidate metastasis modifier gene in breast cancer. Functional gene assays demonstrated that a physical and functional interaction existing between Rrp1b and metastasis modifier gene SIPA1 cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229b48ca76a0353664abdc97e225dcc4
https://pubmed.ncbi.nlm.nih.gov/25277657
https://pubmed.ncbi.nlm.nih.gov/25277657