Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anuradha, Illendula"'
Autor:
Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The ETV6-RUNX1 chimeric- and native RUNX1-responsive regulomes in paediatric B-acute lymphoblastic leukemia (B-ALL) remain to be characterized. Here, the authors reveal functional antagonism between the two transcription factors predominantly for the
Externí odkaz:
https://doaj.org/article/57a324404a3a49c69acb08a4d571d807
Autor:
Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes, Monica L. Guzman, Constanze Bonifer, John H. Bushweller
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 117-131 (2016)
Transcription factors have traditionally been viewed with skepticism as viable drug targets, but they offer the potential for completely novel mechanisms of action that could more effectively address the stem cell like properties, such as self-renewa
Externí odkaz:
https://doaj.org/article/850cfca578ff44cc88f4d9d260010cb6
Autor:
Katelyn E, Salotto, Walter C, Olson, Karlyn E, Pollack, Anuradha, Illendula, Elishama, Michel, Sydney, Henriques, Todd, Fox, Susan, Walker, Marya, Dunlap-Brown, Craig L, Slingluff, Mark, Kester, Helena W, Snyder
Publikováno v:
Cancer Drug Resistance. 5:829-45
Aim: Despite the huge advancements in cancer therapies and treatments over the past decade, most patients with metastasized melanoma still die from the disease. This poor prognosis largely results from resistance to conventional chemotherapies and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36de8ad2e4152dc4489a0778c9fbae69
https://doi.org/10.20517/cdr.2021.132
https://doi.org/10.20517/cdr.2021.132
Autor:
Mark R. Conaway, Denicar Lina Nascimento Fabris Maeda, Mark Kester, Kelly A. Dryden, Vignesh Rajasekaran, Steven L. Zeichner, Andrei Khokhlatchev, Hanna Yu, Claude Chew, Anuradha Illendula
Publikováno v:
ACS Synthetic Biology. 10:2465-2477
Minicells, small cells lacking a chromosome, produced by bacteria with mutated min genes, which control cell division septum placement, have many potential uses. Minicells have contributed to basic bacterial physiology studies and can enable new biot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c343e5893f7693a02e7aca30ff96875b
https://doi.org/10.1021/acssynbio.1c00375
https://doi.org/10.1021/acssynbio.1c00375
Autor:
Ipsita Pal, Anuradha Illendula, John Sanil Manavalan, Todd P Fox, Owen A. O'Connor, Thomas P. Loughran, Mark Kester, David J Feith, Enrica Marchi
Publikováno v:
Blood. 140:8848-8849
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9436f2623ce33d754424a49d32c88f37
https://doi.org/10.1182/blood-2022-167628
https://doi.org/10.1182/blood-2022-167628
Autor:
Jane B. Lian, Jonathan A. R. Gordon, Nicole A. Bouffard, John H. Bushweller, Andrew J. Fritz, Joseph R. Boyd, Sayyed K. Zaidi, Gary S. Stein, Janet L. Stein, Anuradha Illendula, Joshua T. Rose, Eliana Moskovitz
Publikováno v:
Oncotarget
RUNX1 has recently been shown to play an important role in determination of mammary epithelial cell identity. However, mechanisms by which loss of the RUNX1 transcription factor in mammary epithelial cells leads to epithelial-to-mesenchymal transitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c22be5f0cadf1a1bce7aec2bfdde17
http://europepmc.org/articles/PMC7335667
http://europepmc.org/articles/PMC7335667
Autor:
Josefina Doffo, Stefanos A. Bamopoulos, Hazal Köse, Felix Orben, Chuanbing Zang, Miriam Pons, Alexander T. den Dekker, Rutger W. W. Brouwer, Apoorva Baluapuri, Stefan Habringer, Maximillian Reichert, Anuradha Illendula, Oliver H. Krämer, Markus Schick, Elmar Wolf, Wilfred F. J. van IJcken, Irene Esposito, Ulrich Keller, Günter Schneider, Matthias Wirth
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119(9):e2105691119. National Academy of Sciences
Evasion from drug-induced apoptosis is a crucial mechanism of cancer treatment resistance. The proapoptotic protein NOXA marks an aggressive pancreatic ductal adenocarcinoma (PDAC) subtype. To identify drugs that unleash the death-inducing potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61098a89708d34a146809b69f37acdc2
https://pubmed.ncbi.nlm.nih.gov/35197278
https://pubmed.ncbi.nlm.nih.gov/35197278
Autor:
Hanna, Yu, Andrei V, Khokhlatchev, Claude, Chew, Anuradha, Illendula, Mark, Conaway, Kelly, Dryden, Denicar Lina Nascimento Fabris, Maeda, Vignesh, Rajasekaran, Mark, Kester, Steven L, Zeichner
Publikováno v:
ACS synthetic biology. 10(10)
Minicells, small cells lacking a chromosome, produced by bacteria with mutated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a73a0b82620aebc898163ebbbcf0c0ea
https://pubmed.ncbi.nlm.nih.gov/34516078
https://pubmed.ncbi.nlm.nih.gov/34516078
Autor:
Yimin Qian, Warren Fiskus, Christopher P. Mill, David N. Saenz, John H. Bushweller, Tapan M. Kadia, Cristian Coarfa, Dyana T. Saenz, Kanak Raina, Andrew Futreal, Kimal Rajapakshe, Koichi Takahashi, Anuradha Illendula, Michael R. Green, Kapil N. Bhalla, Courtney D. DiNardo, Steven M. Kornblau, Craig M. Crews, Dimuthu Perera, Joseph D. Khoury
Publikováno v:
Blood
RUNX1 transcription factor regulates normal and malignant hematopoiesis. Somatic or germline mutant RUNX1 (mtRUNX1) is associated with poorer outcome in acute myeloid leukemia (AML). Knockdown or inhibition of RUNX1 induced more apoptosis of AML expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2dbd781ff7737120c5745ca6f768cf
https://doi.org/10.1182/blood.2018893982
https://doi.org/10.1182/blood.2018893982
Autor:
Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes, Monica L. Guzman, Constanze Bonifer, John H. Bushweller
Publikováno v:
EBioMedicine, Vol 25, Iss C, p 188 (2017)
Externí odkaz:
https://doaj.org/article/0b1d01d5ffc84fc19361f34993b36b15