Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anura P. Dantanarayana"'
Publikováno v:
Journal of Medicinal Chemistry. 49:318-328
Serotonin 5-HT(2) receptor agonists have been identified as a potential new class of agents for the treatment of ocular hypertension and glaucoma. The initially reported tryptamine analogues displayed either poor solution stability, potent central ne
Autor:
Jesse A. May, Ernest U. Do, Robert Selliah, Judith Egan, Anura P. Dantanarayana, Karen S. Haggard
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:173-183
A method for the preparation of tritium labeled travoprost, a new ocular hypotensive prostaglandin, is described. A highly selective catalytic deiodination has been identified which provides [phenyl-2-3H]-travoprost in a single synthetic step from 2
Autor:
Paul W Zinke, Mark T. DuPriest, Steven J. Sproull, Deason Michael E, and Anura P. Dantanarayana, W. Dennis Dean, Raymond E. Conrow
Publikováno v:
Organic Process Research & Development. 3:114-120
A large scale synthesis of the topical carbonic anhydrase inhibitors AL-4623A (13a·HCl) and AL-4862 (13b) from 3-acetyl-2,5-dichlorothiophene (“DCAT”, 1) is described. Reaction of 1 with NaSBn gave thioether 2, which was converted via sulfenyl c
Publikováno v:
Journal of Heterocyclic Chemistry. 36:65-73
3-(Methoxymethoxymethyl)-2-thiophenesulfonamides and 3-hydroxymethyl-N-methoxymethyl-2-thiophenesulfonamides have been shown to undergo cyclization when treated under anhydrous acidic conditions to provide the novel 2,3-dihydro-5H-thieno[2,3-e]-4,1,2
Autor:
and Anura P. Dantanarayana, Daniel Kuzmich, Steven J. Sproull, Paul W Zinke, Raymond E. Conrow, Mark T. DuPriest
Publikováno v:
The Journal of Organic Chemistry. 62:9372-9375
Autor:
Ulhas S. Warrier, Gary L. Bolton, Roger N. Hiner, Christina M. J. Fox, Anura P. Dantanarayana, Randy W. Jackson, James D. White, Kazuhiko Sakuma
Publikováno v:
ChemInform. 26
Autor:
Paul W Zinke, Raymond E. Conrow, and Anura P. Dantanarayana, Daniel Kuzmich, Steven J. Sproull, Mark T. DuPriest
Publikováno v:
ChemInform. 29
Publikováno v:
ChemInform. 30
3-(Methoxymethoxymethyl)-2-thiophenesulfonamides and 3-hydroxymethyl-N-methoxymethyl-2-thiophenesulfonamides have been shown to undergo cyclization when treated under anhydrous acidic conditions to provide the novel 2,3-dihydro-5H-thieno[2,3-e]-4,1,2
Autor:
Deason Michael E, Raymond E. Conrow, W. Dennis Dean, and Anura P. Dantanarayana, Paul W Zinke, Mark T. DuPriest, Steven J. Sproull
Publikováno v:
ChemInform. 30
A large scale synthesis of the topical carbonic anhydrase inhibitors AL-4623A (13a·HCl) and AL-4862 (13b) from 3-acetyl-2,5-dichlorothiophene (“DCAT”, 1) is described. Reaction of 1 with NaSBn gave thioether 2, which was converted via sulfenyl c
Autor:
James D. White, Anura P. Dantanarayana
Publikováno v:
Tetrahedron Letters. 28:6417-6420
A hexahydrobenzo[AB]furan characteristic of the avermectins and certain milbemycins was synthesized via acid-catalyzed intramolecular addition of a diazoketone to a γ-lactone; subsequent transformations led to structures containing much of the funct