Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Anupma, Nayak"'
Autor:
Jennifer B. Shah, Dana Pueschl, Bradley Wubbenhorst, Mengyao Fan, John Pluta, Kurt D’Andrea, Anna P. Hubert, Jake S. Shilan, Wenting Zhou, Adam A. Kraya, Alba Llop Guevara, Catherine Ruan, Violeta Serra, Judith Balmaña, Michael Feldman, Pat J. Morin, Anupma Nayak, Kara N. Maxwell, Susan M. Domchek, Katherine L. Nathanson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Carriers of pathogenic BRCA1/2 variants have a higher risk of breast and ovarian cancers, which recur frequently. Here, the authors sequence primary and recurrent tumours of BRCA1/2 mutation carriers, finding PARP1 amplifications, differential BRCA2
Externí odkaz:
https://doaj.org/article/86e2b8acb27543e9aad8ac4d1b5b8463
Autor:
Emily J. Gallagher, Kezhen Fei, Sheldon M. Feldman, Elisa Port, Neil B. Friedman, Susan K. Boolbol, Brigid Killelea, Melissa Pilewskie, Lydia Choi, Tari King, Anupma Nayak, Rebeca Franco, Daliz Cruz, Irini M. Antoniou, Derek LeRoith, Nina A. Bickell
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Racial disparities in breast cancer survival between Black and White women persist across all stages of breast cancer. The metabolic syndrome (MetS) of insulin resistance disproportionately affects more Black than White women. It
Externí odkaz:
https://doaj.org/article/dbb802256d2542bdaa3a9fa52e21db53
Autor:
Ajeya Nandi, Rahul Debnath, Anupma Nayak, Tsun Ki Jerrick To, Gatha Thacker, Megan Reilly, Sanjeev Gumber, Ilias Karagounis, Ning Li, Christopher J. Lengner, Malay Haldar, Alana L. Welm, Andres M. Blanco, Christoforos Thomas, Rumela Chakrabarti
Publikováno v:
Cancer Res
Resistance to radiotherapy is a major obstacle for effective cancer treatment. Both cancer-associated fibroblasts (CAF) within the tumor microenvironment (TME) and Notch signaling are implicated in radioresistance, but their potential interrelationsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b09e3f55f58eaba5244cc9c6f77a56
https://doi.org/10.1158/0008-5472.can-21-1225
https://doi.org/10.1158/0008-5472.can-21-1225
Autor:
Qing Chen, Zachary T. Schug, Ashani T. Weeraratna, Maureen E. Murphy, Meenhard Herlyn, Xiaowei Xu, Anupma Nayak, Pulak Ray, Ezra Baraban, Joshua L.D. Parris, Gretchen M. Alicea, Ke Xu, Caroline E. Perry, Nan Cheng, Andrea Watters, Yongkang Zou
Figure S2 shows astrocytes facilitate the growth and survival of brain metastatic cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52297e2b533e08a945df81a22f14d220
https://doi.org/10.1158/2159-8290.22535935.v1
https://doi.org/10.1158/2159-8290.22535935.v1
Autor:
Qing Chen, Zachary T. Schug, Ashani T. Weeraratna, Maureen E. Murphy, Meenhard Herlyn, Xiaowei Xu, Anupma Nayak, Pulak Ray, Ezra Baraban, Joshua L.D. Parris, Gretchen M. Alicea, Ke Xu, Caroline E. Perry, Nan Cheng, Andrea Watters, Yongkang Zou
Brain metastasis, the most lethal form of melanoma and carcinoma, is the consequence of favorable interactions between the invading cancer cells and the brain cells. Peroxisome proliferator–activated receptor γ (PPARγ) has ambiguous functions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d03e40db34df019d18670ce64492bb5f
https://doi.org/10.1158/2159-8290.c.6547984.v1
https://doi.org/10.1158/2159-8290.c.6547984.v1
Publikováno v:
Journal of Surgical Research. 271:154-162
The COX/prostaglandin (COX/PG) pathway plays a role in cancer pathogenesis via the production of prostaglandin E2 (PGE2). In breast cancer, the expression patterns of the COX/PG pathway enzymes involved in PGE2 synthesis are not well defined.Using th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d430f2b22bfaf195d644c0c76256daa
https://doi.org/10.1016/j.jss.2021.08.033
https://doi.org/10.1016/j.jss.2021.08.033
Autor:
Katherine L. Nathanson, Robert H. Vonderheide, Susan M. Domchek, Anupma Nayak, Michael Feldman, Jennifer J.D. Morrissette, Nandita Mitra, Amanda Barrett, Nicole Lunceford, Liza M. Dorfman, Andrew J. Rech, John Pluta, Brandon M. Wenz, Bradley Wubbenhorst, Kara N. Maxwell, Adam A. Kraya
Purpose:Breast cancers with BRCA1/2 alterations have a relatively high mutational load, suggesting that immune checkpoint blockade may be a potential treatment option. However, the degree of immune cell infiltration varies widely, and molecular featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252a400e8c962fb5517f877b6d9a0067
https://doi.org/10.1158/1078-0432.c.6527826
https://doi.org/10.1158/1078-0432.c.6527826
Supplemental Fig. 1: Validation of PTK6 antibody used in immunohistochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481d5fe87c9b9362a87a22d0aef78fcb
https://doi.org/10.1158/0008-5472.22411451.v1
https://doi.org/10.1158/0008-5472.22411451.v1
Supplemental Fig. 5: Cell cycle profile analysis of P21d-treated MDA-MB231 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ed415b51478ca7d19041876e675fe3
https://doi.org/10.1158/0008-5472.22411439
https://doi.org/10.1158/0008-5472.22411439
Autor:
Katherine L. Nathanson, Robert H. Vonderheide, Susan M. Domchek, Anupma Nayak, Michael Feldman, Jennifer J.D. Morrissette, Nandita Mitra, Amanda Barrett, Nicole Lunceford, Liza M. Dorfman, Andrew J. Rech, John Pluta, Brandon M. Wenz, Bradley Wubbenhorst, Kara N. Maxwell, Adam A. Kraya
Supplementary Figures S1-S4, Tables S4, S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742de8fb763cbbc859afff863f907911
https://doi.org/10.1158/1078-0432.22471266
https://doi.org/10.1158/1078-0432.22471266