HR+HER2− breast cancers with growth factor receptor–mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells

Autor: Krisha Desai, Radhika Aiyappa, Jyothi S Prabhu, Madhumathy G Nair, Patrick Varun Lawrence, Aruna Korlimarla, Anupama CE, Annie Alexander, Rohini S Kaluve, Suraj Manjunath, Marjorrie Correa, BS Srinath, Shekhar Patil, Anjali Kalamdani, MSN Prasad, TS Sridhar

Publikováno v: Tumor Biology, Vol 39 (2017)

Despite an overall good prognosis, a significant proportion of patients with hormone receptor positive human epidermal growth factor receptor 2 negative breast cancers develop distant metastases. The metastatic potential of epithelial cells is known

Externí odkaz: https://doaj.org/article/8e7c7acd668d44bc94926d906faa46c6

mHealth app using machine learning to increase physical activity in diabetes and depression: clinical trial protocol for the DIAMANTE Study

Autor: Urmimala Sarkar, Jing Xu, Bibhas Chakraborty, Adrian Aguilera, Caroline A Figueroa, Rosa Hernandez-Ramos, Anupama Cemballi, Laura Gomez-Pathak, Jose Miramontes, Elad Yom-Tov, Xiaoxi Yan, Arghavan Modiri, Jai Aggarwal, Joseph Jay Williams, Courtney R Lyles

Publikováno v: BMJ Open, Vol 10, Iss 8 (2020)

Introduction Depression and diabetes are highly disabling diseases with a high prevalence and high rate of comorbidity, particularly in low-income ethnic minority patients. Though comorbidity increases the risk of adverse outcomes and mortality, most

Externí odkaz: https://doaj.org/article/8dbbcf0f9d91405687add678da8f20de

Differential role of glucocorticoid receptor based on its cell type specific expression on tumor cells and infiltrating lymphocytes.

Autor: Snijesh VP; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India; Centre for Doctoral Studies, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India., Nimbalkar VP; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India., Patil S; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India., Rajarajan S; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India; Centre for Doctoral Studies, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India., Anupama CE; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India., Mahalakshmi S; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India., Alexander A; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India., Soundharya R; IISc Mathematics Initiative, Indian Institute of Science, Bangalore, Karnataka-560012, India., Ramesh R; Department of Surgical Oncology, St. John's Medical College and Hospital, Bangalore, Karnataka, India., Srinath BS; Department of Surgery, Sri Shankara Cancer Hospital and Research Centre, Bangalore, Karnataka, India., Jolly MK; Department of Bioengineering, Indian Institute of Science, Bangalore, Karnataka-560012, India., Prabhu JS; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore, Karnataka, India. Electronic address: jyothi@sjri.res.in.

Publikováno v: Translational oncology [Transl Oncol] 2024 Jul; Vol. 45, pp. 101957. Date of Electronic Publication: 2024 Apr 20.

An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers.

Autor: Rajarajan S; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India; Centre for Doctoral Studies, Manipal Academy of Higher Education (MAHE), Manipal, India., Snijesh VP; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India; Centre for Doctoral Studies, Manipal Academy of Higher Education (MAHE), Manipal, India., Anupama CE; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Nair MG; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Mavatkar AD; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Naidu CM; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Patil S; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Nimbalkar VP; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Alexander A; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India., Pillai M; Centre for BioSystems Science and Engineering, Indian Institute of Science, Bengaluru, India., Jolly MK; Centre for BioSystems Science and Engineering, Indian Institute of Science, Bengaluru, India., Sabarinathan R; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bengaluru, India., Ramesh RS; Department of Surgical Oncology, St. John's Medical College, Bengaluru, India., Bs S; Department of Surgery, Sri Shankara Cancer Hospital and Research Centre, Bangalore, India., Prabhu JS; Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bengaluru, India. Electronic address: jyothi@sjri.res.in.

Publikováno v: Translational oncology [Transl Oncol] 2023 Nov; Vol. 37, pp. 101761. Date of Electronic Publication: 2023 Aug 19.

Abstract PS6-55: The prognostic utility of AR/ER ratio in young women with breast cancer.

Autor: Prabhu JS, Korlimarla A, Rajarajan S, Alexander A, Anupama C, Ramesh R, Srinath B, Sridhar TS

Publikováno v: Cancer research [Cancer Res] 2021 Feb 01; Vol. 81 (4 Suppl). Date of Electronic Publication: 2021 Feb 01 (Print Publication: 2021).