Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Anup Kasi"'
Comparative molecular profiling of pancreatic ductal adenocarcinoma of the head versus body and tail
Autor:
Maen Abdelrahim, Abdullah Esmail, Anup Kasi, Nestor F. Esnaola, Joanne Xiu, Yasmine Baca, Benjamin A. Weinberg
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) of the head (H) and body/tail (B/T) differ in embryonic origin, cell composition, blood supply, lymphatic and venous drainage, and innervation. We aimed to compare the molecular and tumor immune microe
Externí odkaz:
https://doaj.org/article/66e31730210d4f1785ac78732b4c510b
Autor:
Anwaar Saeed, Robin Park, Harsh Pathak, Ayah Nedal Al-Bzour, Junqiang Dai, Milind Phadnis, Raed Al-Rajabi, Anup Kasi, Joaquina Baranda, Weijing Sun, Stephen Williamson, Yu-Chiao Chiu, Hatice Ulku Osmanbeyoglu, Rashna Madan, Hassan Abushukair, Kelly Mulvaney, Andrew K. Godwin, Azhar Saeed
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract CAMILLA is a basket trial (NCT03539822) evaluating cabozantinib plus the ICI durvalumab in chemorefractory gastrointestinal cancer. Herein, are the phase II colorectal cohort results. 29 patients were evaluable. 100% had confirmed pMMR/MSS t
Externí odkaz:
https://doaj.org/article/ef214cc1e88d4bb382653082f8b6a181
Autor:
Ashish Manne, Ashwini Esnakula, Ankur Sheel, Amir Sara, Upender Manne, Ravi Kumar Paluri, Kai He, Wancai Yang, Davendra Sohal, Anup Kasi, Anne M. Noonan, Arjun Mittra, John Hays, Sameek Roychowdhury, Pannaga Malalur, Shafia Rahman, Ning Jin, Jordan M. Cloyd, Susan Tsai, Aslam Ejaz, Kenneth Pitter, Eric Miller, Kannan Thanikachalam, Mary Dillhoff, Lianbo Yu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9041 (2024)
Neoadjuvant therapy (NAT) for early-stage pancreatic ductal adenocarcinoma (PDA) has recently gained prominence. We investigated the clinical significance of mucin 5 AC (MUC5AC), which exists in two major glycoforms, a less-glycosylated immature isof
Externí odkaz:
https://doaj.org/article/b1fab2da00824cabbddfa7f1e921ad46
Autor:
Weijing Sun, Nirmal Veeramachaneni, Raed Al‐Rajabi, Rashna Madan, Anup Kasi, Mazin Al‐Kasspooles, Joaquina Baranda, Anwaar Saeed, Milind A. Phadnis, Andrew K. Godwin, Mojtaba Olyaee, Natalie Streeter, Alykhan Nagji, Junqiang Dai, Stephen Williamson
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16098-16107 (2023)
Abstract Background Perioperative chemotherapy/chemoradiation is standard in esophageal/gastric/gastroesophageal junction (GEJ) adenocarcinoma, immune checkpoint inhibitors (ICI) effect in setting of metastatic and postoperatively. This study is to a
Externí odkaz:
https://doaj.org/article/613b6c3bdc634b1eace9ff580f7c8506
Autor:
Stijn Hentzen, Kathan Mehta, Raed Moh’d Taiseer Al-Rajabi, Anwaar Saeed, Joaquina Celebre Baranda, Stephen K. Williamson, Weijing Sun, Anup Kasi
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 396-405 (2023)
Aim: 177Lu-Dotatate (Lu-177), a form of peptide receptor radionuclide therapy (PRRT), was approved by Food and Drug Administration (FDA) for the treatment of somatostatin-receptor-positive neuroendocrine tumors (NETs) in 2018. Clinical trials prior t
Externí odkaz:
https://doaj.org/article/2635daac99304ae195059b489986adb0
Autor:
Sarah El-Nakeep, Anup Kasi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1ea3b77192cb4b8997032f8ef3fab082
Autor:
Douglas B. Johnson, Michael B. Atkins, Cassandra Hennessy, Trisha Wise-Draper, Hannah Heilman, Joy Awosika, Ziad Bakouny, Chris Labaki, Renee Maria Saliby, Clara Hwang, Sunny R. K. Singh, Nino Balanchivadze, Christopher R. Friese, Leslie A. Fecher, James J. Yoon, Brandon Hayes-Lattin, Mehmet A. Bilen, Cecilia A. Castellano, Gary H. Lyman, Lisa Tachiki, Sumit A. Shah, Michael J. Glover, Daniel B. Flora, Elizabeth Wulff-Burchfield, Anup Kasi, Saqib H. Abbasi, Dimitrios Farmakiotis, Kendra Viera, Elizabeth J. Klein, Lisa B. Weissman, Chinmay Jani, Matthew Puc, Catherine C. Fahey, Daniel Y. Reuben, Sanjay Mishra, Alicia Beeghly-Fadiel, Benjamin French, Jeremy L. Warner, COVID-19 and Cancer Consortium
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Introduction COVID-19 particularly impacted patients with co-morbid conditions, including cancer. Patients with melanoma have not been specifically studied in large numbers. Here, we sought to identify factors that associated with COVID-19 s
Externí odkaz:
https://doaj.org/article/69fb2be87d9e4455bca96362eb3128f6
Autor:
Ian M. Freed, Anup Kasi, Oluwadamilola Fateru, Mengjia Hu, Phasin Gonzalez, Nyla Weatherington, Harsh Pathak, Stephen Hyter, Weijing Sun, Raed Al-Rajabi, Joaquina Baranda, Mateusz L. Hupert, Prabhakar Chalise, Andrew K. Godwin, Malgorzata A. Witek, Steven A. Soper
Publikováno v:
Cells, Vol 12, Iss 18, p 2266 (2023)
There is a high clinical unmet need to improve outcomes for pancreatic ductal adenocarcinoma (PDAC) patients, either with the discovery of new therapies or biomarkers that can track response to treatment more efficiently than imaging. We report an in
Externí odkaz:
https://doaj.org/article/9fecc40105aa4e958c30860a3c5755e3
Autor:
Anusha Chidharla, Eliot Rapoport, Kriti Agarwal, Samragnyi Madala, Brenda Linares, Weijing Sun, Sakti Chakrabarti, Anup Kasi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10230 (2023)
Emerging data have suggested that circulating tumor DNA (ctDNA) can be a reliable biomarker for minimal residual disease (MRD) in CRC patients. Recent studies have shown that the ability to detect MRD using ctDNA assay after curative-intent surgery w
Externí odkaz:
https://doaj.org/article/9a35b4da1d30425a976ed343eb5cc81c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8087 (2023)
Mucin 5AC (MUC5AC) glycoprotein plays a crucial role in carcinogenesis and drug sensitivity in pancreatic ductal adenocarcinoma (PDAC), both individually and in combination with other mucins. Its function and localization are glycoform-specific. The
Externí odkaz:
https://doaj.org/article/9668083610104666ab4545ec736c34ed