Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Anup Dey"'
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 32124-32132 (2024)
Externí odkaz:
https://doaj.org/article/38b5181f83094194a82e1a4972e32dbc
Bromodomain protein BRD4 directs mitotic cell division of mouse fibroblasts by inhibiting DNA damage
Autor:
Tiyun Wu, Haitong Hou, Anup Dey, Mahesh Bachu, Xiongfong Chen, Jan Wisniewski, Fuki Kudoh, Chao Chen, Sakshi Chauhan, Hua Xiao, Richard Pan, Keiko Ozato
Publikováno v:
iScience, Vol 27, Iss 7, Pp 109797- (2024)
Summary: Bromodomain protein BRD4 binds to acetylated histones to regulate transcription. BRD4 also drives cancer cell proliferation. However, the role of BRD4 in normal cell growth has remained unclear. Here, we investigated this question by using m
Externí odkaz:
https://doaj.org/article/cfc5cbda4d44456fada9dd9003dd13e3
Autor:
Anuradha Gupta, Jungmi Lee, Torsha Ghosh, Van Quy Nguyen, Anup Dey, Been Yoon, Wooram Um, Jae Hyung Park
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 540 (2022)
Rheumatoid arthritis (RA) and osteoarthritis (OA) are disabling musculoskeletal disorders that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of anti-arthritic agents is limited due to short intra-articular half-
Externí odkaz:
https://doaj.org/article/c49ff1a4955e41e8b180914028697583
Autor:
Chao Chen, Ming-an Sun, Claude Warzecha, Mahesh Bachu, Anup Dey, Tiyun Wu, Peter D Adams, Todd Macfarlan, Paul Love, Keiko Ozato
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2136-2149.e4 (2020)
Summary: HIRA is a histone chaperone that deposits the histone variant H3.3 in transcriptionally active genes. In DiGeorge syndromes, a DNA stretch encompassing HIRA is deleted. The syndromes manifest varied abnormalities, including immunodeficiency
Externí odkaz:
https://doaj.org/article/482cd898b9bd4c2a898c0a6bb9d4a8ec
Autor:
Anne Gegonne, Qing-Rong Chen, Anup Dey, Ruth Etzensperger, Xuguang Tai, Alfred Singer, Daoud Meerzaman, Keiko Ozato, Dinah S. Singer
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 117-129 (2018)
Summary: T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly dist
Externí odkaz:
https://doaj.org/article/69f3e19e9a5c4397a55ab00523c4b6eb
Autor:
Ji-Eun Lee, Young-Kwon Park, Sarah Park, Younghoon Jang, Nicholas Waring, Anup Dey, Keiko Ozato, Binbin Lai, Weiqun Peng, Kai Ge
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Despite being an important cancer drug target, the role of epigenetic reader Brd4 in cell differentiation and development remains unclear. Here, the authors provide evidence that Brd4 plays an important role in adipogenesis and myogenesis by binding
Externí odkaz:
https://doaj.org/article/4a7139498fa741c093bf16e3320affb8
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e34719 (2012)
Some anti-cancer drugs, including those that alter microtubule dynamics target mitotic cells and induce apoptosis in some cell types. However, such drugs elicit protective responses in other cell types allowing cells to escape from drug-induced mitot
Externí odkaz:
https://doaj.org/article/2d5abe21781141ce8b2b279b9e1ecdec
Publikováno v:
Journal of Controlled Release. 358:555-565
Publikováno v:
Journal of Controlled Release. 352:179-198
Nitric oxide (NO) is an endogenous, multipotent biological signaling molecule that participates in several physiological processes. Recently, exogenous supplementation of tumor tissues with NO has emerged as a potential anticancer therapy. In particu
Publikováno v:
Chemistry of Materials. 34:7741-7749