Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Anukul T Shenoy"'
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204032 (2018)
Streptococcus pneumoniae is an opportunistic Gram-positive pathogen that can cause invasive disease. Recent studies have shown that S. pneumoniae is able to invade the myocardium and kill cardiomyocytes, with one-in-five adults hospitalized for pneum
Externí odkaz:
https://doaj.org/article/71b51f2e71ab46abaff37ae5d7bb1494
Autor:
Anukul T Shenoy, Terry Brissac, Ryan P Gilley, Nikhil Kumar, Yong Wang, Norberto Gonzalez-Juarbe, Whitney S Hinkle, Sean C Daugherty, Amol C Shetty, Sandra Ott, Luke J Tallon, Jessy Deshane, Hervé Tettelin, Carlos J Orihuela
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006582 (2017)
For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocar
Externí odkaz:
https://doaj.org/article/ab3eee1c889049c0b3060857d0f4005e
Autor:
Luis F Reyes, Marcos I Restrepo, Cecilia A Hinojosa, Nilam J Soni, Anukul T Shenoy, Ryan P Gilley, Norberto Gonzalez-Juarbe, Julio R Noda, Vicki T Winter, Melissa A de la Garza, Robert E Shade, Jacqueline J Coalson, Luis D Giavedoni, Antonio Anzueto, Carlos J Orihuela
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166092 (2016)
RATIONALE:Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and infectious death in adults worldwide. A non-human primate model is needed to study the molecular mechanisms that underlie the development of severe pneumonia,
Externí odkaz:
https://doaj.org/article/b37a6465e5f543778679681819181fb9
Autor:
Neelou S. Etesami, Kimberly A. Barker, Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Gabrielle N. Grifno, Adeline M. Matschulat, Michael E. Vannini, Riley M. F. Pihl, Michael P. Breen, Alicia M. Soucy, Wesley N. Goltry, Catherine T. Ha, Hanae Betsuyaku, Jeffrey L. Browning, Xaralabos Varelas, Katrina E. Traber, Matthew R. Jones, Lee J. Quinton, Paul J. Maglione, Hadi T. Nia, Anna C. Belkina, Joseph P. Mizgerd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recovery from respiratory pneumococcal infections generates lung-localized protection against heterotypic bacteria, mediated by resident memory lymphocytes. Optimal protection in mice requires re-exposure to pneumococcus within days of initial infect
Externí odkaz:
https://doaj.org/article/49ecad14795045e78212ea23aeaa9d05
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0fec9961ffaa4b08962383083e06ba54
Autor:
Filiz T. Korkmaz, Anukul T. Shenoy, Elise M. Symer, Lillia A. Baird, Christine V. Odom, Emad I. Arafa, Ernest L. Dimbo, Elim Na, William Molina-Arocho, Matthew Brudner, Theodore J. Standiford, Jawahar L. Mehta, Tatsuya Sawamura, Matthew R. Jones, Joseph P. Mizgerd, Katrina E. Traber, Lee J. Quinton
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Identifying host factors that contribute to pneumonia incidence and severity are of utmost importance to guiding the development of more effective therapies. Lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1, encoded by OLR1) is a scaven
Externí odkaz:
https://doaj.org/article/b320f241dc9942bba46957a1d10f8c08
Autor:
Elim Na, Eri Allen, Lillia A. Baird, Christine V. Odom, Filiz T. Korkmaz, Anukul T. Shenoy, Adeline M. Matschulat, Matthew R. Jones, Darrell N. Kotton, Joseph P. Mizgerd, Xaralabos Varelas, Katrina E. Traber, Lee J. Quinton
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
During bacterial pneumonia, alveolar epithelial cells are critical for maintaining gas exchange and providing antimicrobial as well as pro-immune properties. We previously demonstrated that leukemia inhibitory factor (LIF), an IL-6 family cytokine, i
Autor:
Carolina Lyon De Ana, Kimberly A. Barker, Joseph P. Mizgerd, Anukul T. Shenoy, E.I. Arafa, I.M.C. Martin, Anna C. Belkina
Publikováno v:
Cytometry Part A. 101:892-902
Recovery from pneumococcal (Spn) pneumonia induces development of tissue resident memory CD4+ TRM cells, BRM cells, and antibody secreting plasma cells in experienced lungs. These tissue resident lymphocytes confer protection against subsequent letha
Autor:
Anne Hinds, E.I. Arafa, Anukul T. Shenoy, Thomas Braun, Matthew R. Jones, Carolina Lyon De Ana, Filiz Korkmaz, Aditya Ramanujan, Neelou S. Etesami, Kimberly A. Barker, Hasmeena Kathuria, Joseph P. Mizgerd, Alicia M. Soucy, Anna C. Belkina, Brian R. Tilton, Wesley N. Goltry, I.M.C. Martin, Isabelle Salwig, Lee J. Quinton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Barrier tissues are populated by functionally plastic CD4+ resident memory T (TRM) cells. Whether the barrier epithelium regulates CD4+ TRM cell locations, plasticity and activities remains unclear. Here we report that lung epithelial cells, includin
Autor:
Emad I. Arafa, Anukul T. Shenoy, Kimberly A. Barker, Neelou S. Etesami, Ian M.C. Martin, Carolina Lyon De Ana, Elim Na, Christine V. Odom, Wesley N. Goltry, Filiz T. Korkmaz, Alicia K. Wooten, Anna C. Belkina, Antoine Guillon, E. Camilla Forsberg, Matthew R. Jones, Lee J. Quinton, Joseph P. Mizgerd
Publikováno v:
JCI Insight. 7
Recovery from pneumococcal pneumonia remodels the pool of alveolar macrophages so that they exhibit new surface marker profiles, transcriptomes, metabolomes, and responses to infection. Mechanisms mediating alveolar macrophage phenotypes after pneumo