Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Anuk Das"'
Autor:
Lauren A. Peters, Joshua R. Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Tetyana Dodatko, Mariana P. Amaro, Paula Restrepo, Zhi Chai, J. Rodrigo Mora, Holly A. Raymond, Mark Curran, Radu Dobrin, Anuk Das, Huabao Xiong, Eric E. Schadt, Carmen Argmann, Bojan Losic
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Longitudinal changes in gene expression, splicing patterns and adaptive immune repertoire in murine models of colitis are examined and associated with histologic inflammation in mice and in patients with inflammatory bowel disease.
Externí odkaz:
https://doaj.org/article/95a2a99b4f784d3c91deb9675e5c43a3
Autor:
Polina Mamontov, Ryan A Eberwine, Jackie Perrigoue, Anuk Das, Joshua R Friedman, J Rodrigo Mora
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215963 (2019)
The Tec kinases ITK (interleukin-2-inducible T-cell kinase) and RLK (resting lymphocyte kinase) are critical components of the proximal TCR/CD3 signal transduction machinery, and data in mice suggest that ITK negatively modulates regulatory T cell (T
Externí odkaz:
https://doaj.org/article/8853e7c836eb4e90bb43fafce71d9669
Autor:
Matthew K. Doherty, Tao Ding, Charlie Koumpouras, Shannon E. Telesco, Calixte Monast, Anuk Das, Carrie Brodmerkel, Patrick D. Schloss
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The fecal microbiota is a rich source of biomarkers that have previously been shown to be predictive of numerous disease states. Less well studied is the effect of immunomodulatory therapy on the microbiota and its role in response to therap
Externí odkaz:
https://doaj.org/article/1babf2df203b4e62b518a9c7af952e71
Autor:
Varun Aggarwala, Hazel M. Mitchell, Nadeem O. Kaakoush, Marla Dubinsky, Michael A. Kamm, Anuk Das, Ari Grinspan, Dirk Gevers, Belgin Dogan, Eduardo J. Contijoch, Graham J. Britton, Jeremiah J. Faith, Kenneth W. Simpson, Matthew P. Spindler, Jose C. Clemente, Lani San Mateo, Sudarshan Paramsothy, Gerold Bongers, Andrew Baltus, Jean-Frederic Colombel, Thomas J. Borody
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Composition of gut microbiota is altered in many human diseases, including inflammatory bowel disease. Some hope that restoring microbiota to a healthy state could help treat such diseases. We have used mice colonized with microbiotas fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc8acd9bdc846dc5ec0555226559198
http://europepmc.org/articles/PMC7474624
http://europepmc.org/articles/PMC7474624
Autor:
Yongzhong Zhao, Mark E. Curran, Hardik Shah, Mary Beth Humphrey, Jeremiah J. Faith, Eunjee Lee, Arthur Mortha, Lauren A. Peters, Bojan Losic, Anuk Das, Brian A. Kidd, Eric M. Neiman, Sean R. Llewellyn, Radu Dobrin, Panos Roussos, Riccardo Miotto, Teresa K. Tarrant, Joshua R. Friedman, Antonio Fabio Di Narzo, Khader Shameer, Won-Min Song, Jun Zhu, Bin Zhang, Carmen Argmann, Eric E. Schadt, Alina Iuga, Carrie Brodmerkel, Jacqueline Perrigoue, Lloyd Mayer, Andrew Kasarskis, Yoshinori Fukui, Aleksandar Stojmirović, Jocelyn Sendecki, Brian M. Iritani, Shannon Telesco, Minghui Wang, Nicholas E.S. Sibinga, Ke Hao
Publikováno v:
Nature genetics
A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data sets to construct predictive models of IBD. We present a predictive model of the immune component of IBD that informs causal relationships among loci previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195b6f77b244f06c980eb2413de861c8
http://europepmc.org/articles/PMC5660607
http://europepmc.org/articles/PMC5660607
Autor:
Jose C. Clemente, Michael A. Kamm, Graham J. Britton, Anuk Das, Ari Grinspan, Andrew Baltus, Lani San Mateo, Hazel M. Mitchell, Jeremiah J. Faith, Varun Aggarwala, Gerold Bongers, Sudarshan Paramsothy, Matthew P. Spindler, Eduardo J. Contijoch, Marla Dubinsky, Nadeem O. Kaakoush, Dirk Gevers, Thomas J. Borody, Jean-Frederic Colombel
The building evidence for the contribution of microbiota to human disease has spurred an effort to develop therapies that target the gut microbiota. This is particularly evident in inflammatory bowel diseases, where clinical trials of fecal microbiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a1d29d275c6ae9830d3a0b1da481a5
https://doi.org/10.1101/844662
https://doi.org/10.1101/844662
Autor:
Joshua R. Friedman, Polina Mamontov, Jackie Perrigoue, Ryan A. Eberwine, Anuk Das, J. Rodrigo Mora
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215963 (2019)
PLoS ONE
PLoS ONE
The Tec kinases ITK (interleukin-2-inducible T-cell kinase) and RLK (resting lymphocyte kinase) are critical components of the proximal TCR/CD3 signal transduction machinery, and data in mice suggest that ITK negatively regulates TREG differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fda83f2651ee0852ff5cb5bea44202
https://doaj.org/article/8853e7c836eb4e90bb43fafce71d9669
https://doaj.org/article/8853e7c836eb4e90bb43fafce71d9669
Autor:
Graham J, Britton, Eduardo J, Contijoch, Ilaria, Mogno, Olivia H, Vennaro, Sean R, Llewellyn, Ruby, Ng, Zhihua, Li, Arthur, Mortha, Miriam, Merad, Anuk, Das, Dirk, Gevers, Dermot P B, McGovern, Namita, Singh, Jonathan, Braun, Jonathan P, Jacobs, Jose C, Clemente, Ari, Grinspan, Bruce E, Sands, Jean-Frederic, Colombel, Marla C, Dubinsky, Jeremiah J, Faith
Publikováno v:
Immunity. 50(1)
Microbiota are thought to influence the development and progression of inflammatory bowel disease (IBD), but determining generalizable effects of microbiota on IBD etiology requires larger-scale functional analyses. We colonized germ-free mice with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::914f58e1db89360b2aa92a72f854dd3c
https://pubmed.ncbi.nlm.nih.gov/31230082
https://pubmed.ncbi.nlm.nih.gov/31230082
Autor:
Anuk Das, Jonathan Braun, Marla Dubinsky, Eduardo J. Contijoch, Dermot P.B. McGovern, Bruce E. Sands, Dirk Gevers, J.-F. Colombel, Jose C. Clemente, Ilaria Mogno, Olivia H. Vennaro, Arthur Mortha, Miriam Merad, Graham J. Britton, Ruby Ng, Namita Singh, Zihai Li, Sean R. Llewellyn, Ari Grinspan, Jeremiah J. Faith, Jonathan P. Jacobs
To examine the functional contribution of Inflammatory Bowel Disease (IBD) microbes to immune homeostasis and colitis, we colonized unchallenged and colitis-susceptible germ-free mice with over twenty human intestinal microbiotas from healthy and IBD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219cd0e8e3f71e6d3ab8cc3a92414269
https://doi.org/10.1101/276774
https://doi.org/10.1101/276774
Autor:
Anuk Das, Jeremiah J. Faith, Miriam Merad, Dermot P.B. McGovern, Olivia H. Vennaro, Arthur Mortha, Eduardo J. Contijoch, Jean-Frederic Colombel, Dirk Gevers, Bruce E. Sands, Jonathan Braun, Ruby Ng, Jonathan P. Jacobs, Namita Singh, Jose C. Clemente, Sean R. Llewellyn, Ari Grinspan, Ilaria Mogno, Marla Dubinsky, Graham J. Britton, Zhihua Li
Publikováno v:
Immunity. 50:212-224.e4
Summary Microbiota are thought to influence the development and progression of inflammatory bowel disease (IBD), but determining generalizable effects of microbiota on IBD etiology requires larger-scale functional analyses. We colonized germ-free mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468c2b3f595cf02b7680bb4760951cc6
https://doi.org/10.1016/j.immuni.2018.12.015
https://doi.org/10.1016/j.immuni.2018.12.015