Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Anuja Premawardhena"'
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Introduction Anaemia occurs due to an imbalance between erythrocyte production and loss. This imbalance can be due to ineffective erythropoiesis, blood loss or haemolysis. Whilst there are many causes for anaemia, iron deficiency anaemia (IDA) remain
Externí odkaz:
https://doaj.org/article/92653c6825fd4a5b9d07dc654f6484d0
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-5 (2023)
Abstract Background Sepsis and thrombo-embolic disease are well known complications of thalassemia major. Intracardiac thrombi are however rare and can lead to diagnostic dilemmas. Case presentation We report the case of a 20-year-old female splenect
Externí odkaz:
https://doaj.org/article/e5f4949a85a446beb031dc20308f69b1
Autor:
Anuja Premawardhena, Sachith Mettananda, Chamodi Perera, Muditha Nayana Wijethilaka, Sakuni Keshani Wanasinghe, R H M G Rajakaruna, R A N K K Samarasinghe, Senani Williams
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Despite the improvement in medical management, many patients with transfusion-dependent β-thalassaemia die prematurely due to transfusion-related iron overload. As per the current guidelines, the optimal chelation of iron cannot be achi
Externí odkaz:
https://doaj.org/article/128305d316984abc81f10f1f0003ccdd
Autor:
Anuja Premawardhena, Shamila De Silva, Megha Rajapaksha, Vishaka Ratnamalala, Jemimah Nallarajah, Gamini Galappatthy
Publikováno v:
International Journal of Emergency Medicine, Vol 16, Iss 1, Pp 1-4 (2023)
Abstract Background Cardiac disease remains a dominant if not the most important cause of morbidity and mortality in patients with thalassaemia, particularly in those with thalassaemia major. Myocardial infarction and coronary artery disease however
Externí odkaz:
https://doaj.org/article/58c50ac93afe4d748a43f5f04bfce270
Autor:
Rusiru Premathilaka, Thamal Darshana, Chanil Ekanayake, Kossinnage Chethana Chathurangani, Iroshan Mendis, Sajeethan Perinparajah, Madhushini Shashiprabha, Sachith Nishshanka, Yasoma Tilakaratna, Anuja Premawardhena
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Despite advancements in diagnostic technology, pyrexia of unknown origin (PUO) remains a clinical concern. Insufficient information is available regarding the cost of care for the management of PUO in the South Asian Region. Metho
Externí odkaz:
https://doaj.org/article/e39203c7772547fda0325d7e6777450e
Autor:
Nadeeja Amarasinghe, Amila Amarasena, Anoj Thabrew, Prabhath Werawatte, Anuja Premawardhena, Farnaz Malik, Mohamed Abusayeed, Champika Wickramasinghe
Publikováno v:
Thalassemia Reports, Vol 12, Iss 4, Pp 135-142 (2022)
Sri Lanka, a country with 22 million people, has nearly 2000 thalassemia patients with severe thalassemia, two-thirds of whom have beta thalassemia major (TM). The current prevention program based on promoting “safe marriages”, which has been in
Externí odkaz:
https://doaj.org/article/e5a7ea7d682240e48c04dde14621ca31
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Although considered a mild clinical condition, many laboratory issues of the carrier state of β-thalassemia remain unresolved. Accurate laboratory screening of β-thalassemia traits is crucial for preventing the birth of a β-thalassemia major child
Externí odkaz:
https://doaj.org/article/70b74f3734934601811d65e898f413b0
Autor:
Nirmani Yasara, Nethmi Wickramarathne, Chamila Mettananda, Ishari Silva, Nizri Hameed, Kumari Attanayaka, Rexan Rodrigo, Nirmani Wickramasinghe, Lakshman Perera, Aresha Manamperi, Anuja Premawardhena, Sachith Mettananda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hydroxyurea is an antimetabolite drug that induces fetal haemoglobin in sickle cell disease. However, its clinical usefulness in β-thalassaemia is unproven. We conducted a randomised, double-blind, placebo-controlled clinical trial to evalu
Externí odkaz:
https://doaj.org/article/4cc1a47132c94b1ba3eb73830eb877e0
Autor:
Dileepa Senajith Ediriweera, Madunil Anuk Niriella, Anuja Premawardhena, Padmapani Padeniya, Arjuna P. De Silva
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Objective To evaluate the performance of the fibrosis-4 (FIB-4) score as a screening tool to detect significant liver fibrosis (F2) compared with transient elastography (TE), among chronic transfusion-dependent beta-thalassaemia (TDT) patients in a r
Externí odkaz:
https://doaj.org/article/059f6b7a1ab64852998a919ed03e253d
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background Hydroxyurea is one of the earliest drugs that showed promise in the management of haemoglobinopathies that include β-thalassaemia and sickle cell disease. Despite this, many aspects of hydroxyurea are either unknown or understudi
Externí odkaz:
https://doaj.org/article/c561ef68190d41c2b939ad2e9a3d7366