Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anuja Chattopadhyay"'
Supplementary Figure 1. TNF-alpha induced apoptosis. Cells were treated with 2.5 ng/ml TNF-alpha and 250 ng/ml CHX, ethanol fixed, and stained with PI. The percentage of cells containing sub-G/G1 DNA content was assessed by flow cytometry at time 0,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b71c778cf59302d9cc7ef6a202d2cd
https://doi.org/10.1158/1541-7786.22511914
https://doi.org/10.1158/1541-7786.22511914
A subset of acute promyelocytic leukemia (APL) cases has been characterized by the t(5;17)(q35;q21) translocation variant, which fuses nucleophosmin (NPM) to retinoic acid receptor α (RARA). The resultant NPM-RAR fusion protein blocks myeloid differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822e483361943dd49b3185519dc26173
https://doi.org/10.1158/1541-7786.c.6540073.v1
https://doi.org/10.1158/1541-7786.c.6540073.v1
Publikováno v:
Leukemia & Lymphoma. 57:1933-1937
The variant acute promyelocytic leukemia (APL) translocation t(5;17)(q35;q21) fuses the N-terminus of nucleophosmin (NPM1) to the retinoic acid receptor alpha (RARA). We found that ectopic NPM1-RARA expression decreased TP53 protein levels in target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c992d8068a6fc91ea01ad1ecbaa0d3e1
https://doi.org/10.3109/10428194.2015.1124992
https://doi.org/10.3109/10428194.2015.1124992
Publikováno v:
Leukemia & Lymphoma. 56:3401-3406
The t(5;17) variant of acute promeylocytic leukemia (APL) expresses a fusion of nucleophosmin (NPM) with the retinoic acid receptor alpha (RARA). We have previously shown that NPM-RAR is a binding partner of the tumor necrosis factor (TNF) receptor t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a21c98bf761134ea454ede0e37ad9a
https://doi.org/10.3109/10428194.2015.1023799
https://doi.org/10.3109/10428194.2015.1023799
Autor:
John Piwowar, Alan Wells, Anuja Chattopadhyay, Paul Kornblith, Michael J. Gabrin, Lisa D. George, Robert L. Ochs, Dennis R Burholt
Publikováno v:
International Journal of Gynecological Cancer. 14:607-615
The treatment of ovarian cancer principally relies on the use of platinum and taxane chemotherapeutic agents. Short-term clinical results have been encouraging, but long-term responses remain limited. In this report, an in vitro assay system that uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03e5ed785e3f3a51ab2548b5e032082
https://doi.org/10.1111/j.1048-891x.2004.14408.x
https://doi.org/10.1111/j.1048-891x.2004.14408.x
Autor:
Anuja Chattopadhyay, Elizabeth Yang, C. Michael Knudson, Linda Z. Penn, Erinn L. Soucie, Courtney G. Sansam, Yelena M. Janumyan, Ningli Cheng, David W. Andrews
Publikováno v:
The EMBO Journal. 22:5459-5470
Bcl-x(L) and Bcl-2 inhibit both apoptosis and proliferation. In investigating the relationship between these two functions of Bcl-x(L) and Bcl-2, an analysis of 24 Bcl-x(L) and Bcl-2 mutant alleles, including substitutions at residue Y28 previously r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ea292584f5fcbedb5ed2cb8cee87f2
https://doi.org/10.1093/emboj/cdg533
https://doi.org/10.1093/emboj/cdg533
Autor:
Robert L. Redner, Anuja Chattopadhyay
Publikováno v:
Cancer genetics and cytogenetics. 201(1)
We studied a case of a 72-year-old man with acute promyelocytic leukemia and a t(3;17)(p25;q21). Fluorescence in situ hybridization failed to show rearrangement of the PML (promyelocytic leukemia protein) locus but did demonstrate relocalization of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4770a75a08b3a85fbc157271bc2f0e20
https://pubmed.ncbi.nlm.nih.gov/20633765
https://pubmed.ncbi.nlm.nih.gov/20633765
Autor:
Paul, Kornblith, Alan, Wells, Michael J, Gabrin, John, Piwowar, Anuja, Chattopadhyay, Lisa D, George, Robert L, Ochs, Dennis, Burholt
Publikováno v:
Anticancer research. 23(1B)
We describe the in vitro patterns of response of explanted primary and recurrent ovarian cancers to platinum- and taxane-based chemotherapeutics. The chemoresponse assay utilizes cells that grow out from tumor fragments and are then challenged with v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9faca395a7c4a04d2ae0138c976bd25
https://pubmed.ncbi.nlm.nih.gov/12680143
https://pubmed.ncbi.nlm.nih.gov/12680143
Publikováno v:
Oncogene. 21(51)
The anti-apoptotic molecules BCL-x(L) and BCL2 delay cell cycle entry from quiescence. We used serum induction and induction of a Myc-estrogen receptor fusion protein (MycER) in quiescent fibroblasts to investigate the mechanisms underlying the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb40ab21b09bd75fa39ba185b69103ed
https://pubmed.ncbi.nlm.nih.gov/12420213
https://pubmed.ncbi.nlm.nih.gov/12420213
Publikováno v:
Oncogene. 20(33)
The pro-apoptotic molecule BAD binds BCL-[X(L)] or BCL2 and inactivates their survival function. In addition to their anti-apoptotic function, BCL2 and BCL-[X(L)] also delay cell cycle entry from quiescence. We found that the BH3-only molecule BAD al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fdefb9d4ec92c23cc68cce1310ac6a
https://pubmed.ncbi.nlm.nih.gov/11494146
https://pubmed.ncbi.nlm.nih.gov/11494146