Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anuj Gahlawat"'
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Numerous computational methods, including evolutionary-based, energy-based, and geometrical-based methods, are utilized to identify cavities inside proteins. Cavity information aids protein function annotation, drug design, poly-pharmacology
Externí odkaz:
https://doaj.org/article/33b51ef73a99486bbb218f83bf05fff6
The aim of the study was to validate Nuclear receptor-binding SET Domain NSD1 as a cancer drug target followed by the design of lead molecules against NSD1. TCGA clinical data, molecular expression techniques were used to validate the target and stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03b84d992f76d6eda2d520f322d23ea
https://doi.org/10.21203/rs.3.rs-2917843/v1
https://doi.org/10.21203/rs.3.rs-2917843/v1
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:2878-2892
Alzheimer���s disease (AD) is one of the most familiar multifactorial and complex neurodegenerative disorders characterized by loss of cholinergic neurons in the brain. The various attempts for drug development to treat AD have been hampered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bb1cd24985b628617c592a3c37d391
https://doi.org/10.1080/07391102.2020.1844054
https://doi.org/10.1080/07391102.2020.1844054
Autor:
Prabha Garg, Hardeep Sandhu, Anuj Gahlawat, Inder Pal Singh, Anders Sjöstedt, Navneet Kumar, Rajender Kumar, Saranjit Singh
Publikováno v:
Journal of Chemical Information and Modeling
The COVID-19 disease is caused by a new strain of the coronavirus family (SARS-CoV-2), and it has affected at present millions of people all over the world. The indispensable role of the main protease (Mpro) in viral replication and gene expression m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ea958543640f0349a50d43bb9d94b1
https://doi.org/10.1021/acs.jcim.0c00546
https://doi.org/10.1021/acs.jcim.0c00546
Autor:
Anuj Gahlawat, Kousar Jahan, Chaitanya K. Jaladanki, Prasad V. Bharatam, Hardeep Sandhu, Gajanan Rathod
Publikováno v:
Drug Metabolism Reviews. 52:366-394
Cytochromes P450 are oxidizing enzymes; a few families of cytochromes P450 are implicated in drug metabolism. These enzymatic reactions involve many processes including (i) prodrug to drug conversion, (ii) easy excretion of drug, (iii) generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2caf0fe3e2fe4a0dd6e68e77b70fa3
https://doi.org/10.1080/03602532.2020.1765792
https://doi.org/10.1080/03602532.2020.1765792
Autor:
Ramesh Nimma, Ajay Kumar, Zahid Gani, Anuj Gahlawat, Rahul Dilawari, Rajesh Kumar Rohilla, Hemangi Kumbhar, Prabha Garg, Sidharth Chopra, Manoj Raje, Chaaya Iyengar Raje
Publikováno v:
Microbial Pathogenesis. 175:105992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6b43e6dcdc249a0a3c609169c3782f5
https://doi.org/10.1016/j.micpath.2023.105992
https://doi.org/10.1016/j.micpath.2023.105992
Autor:
Navneet, Kumar, Anuj, Gahlawat, Rajaram Naresh, Kumar, Yash Pal, Singh, Gyan, Modi, Prabha, Garg
Publikováno v:
Journal of biomolecular structuredynamics. 40(7)
Alzheimer's disease (AD) is one of the most familiar multifactorial and complex neurodegenerative disorders characterized by loss of cholinergic neurons in the brain. The various attempts for drug development to treat AD have been hampered by largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97ac43bdf90fee8235f0f0541bcd20e0
https://pubmed.ncbi.nlm.nih.gov/33170091
https://pubmed.ncbi.nlm.nih.gov/33170091
Publikováno v:
Challenges and Advances in Computational Chemistry and Physics ISBN: 9783030052812
Structure-based drug design (SBDD) is being efficiently used for the design of antimalarial agents. It is a very effective tool for challenges like drug selectivity and resistance. Over the past decade, a considerable number of druggable targets have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7fda79ef2ab40d6bddf600ac2c9a322
https://doi.org/10.1007/978-3-030-05282-9_6
https://doi.org/10.1007/978-3-030-05282-9_6