Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anubhav Tamrakar"'
Autor:
Ankit Jaiswal, Rajarshi Roy, Anubhav Tamrakar, Amit Kumar Singh, Parimal Kar, Prashant Kodgire
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Activation-induced cytidine deaminase (AID) is the key mediator of antibody diversification in activated B-cells by the process of somatic hypermutation (SHM) and class switch recombination (CSR). Targeting AID to the Ig genes requires trans
Externí odkaz:
https://doaj.org/article/893d78a10031416283f8d7dfa4b726c3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Helicobacter pylori is a Gram-negative bacterium that causes chronic inflammations in the stomach area and is involved in ulcers, which can develop into gastric malignancies. H. pylori attaches and colonizes to the human epithelium using som
Externí odkaz:
https://doaj.org/article/97108b7437554748ad2348e55e151181
Publikováno v:
International Reviews of Immunology. 40:289-306
Activated B-cells diversify their antibody repertoire via somatic hypermutation (SHM) and class switch recombination (CSR). SHM is restricted to the variable region, whereas, CSR is confined to the constant region of immunoglobulin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c3f43b1b12fdfe93ab2905c45fee03
https://doi.org/10.1080/08830185.2020.1815725
https://doi.org/10.1080/08830185.2020.1815725
Publikováno v:
Molecular Immunology. 119:69-82
SRSF1, a member of the SR protein family, is an important splicing factor and regulator of splicing. Multiple splicing isoforms have been reported for this gene. SRSF1-3, a splicing isoform of SRSF1, is necessary for AID-dependent SHM of IgV genes. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd365a3c3387a87acc97efc43e61dc4f
https://doi.org/10.1016/j.molimm.2020.01.005
https://doi.org/10.1016/j.molimm.2020.01.005
Autor:
Anshu Agarwal, Ankit Jaiswal, Amit Kumar Singh, Anubhav Tamrakar, Prashant Kodgire, Prabhanshu Tripathi, Naoki Kanayama
Publikováno v:
Molecular Immunology. 116:63-72
Somatic hypermutation (SHM) of Ig genes is initiated by activation-induced cytidine deaminase (AID) and requires target gene transcription. A splice isoform of SRSF1, SRSF1-3, is necessary for AID-dependent SHM of IgV genes. Nevertheless, its exact m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633df14e91cff02b4d68f15dfaf3173a
https://doi.org/10.1016/j.molimm.2019.10.002
https://doi.org/10.1016/j.molimm.2019.10.002
Autor:
Anubhav Tamrakar, Prashant Kodgire
Publikováno v:
Molecular immunology. 142
H. pylori is one of the major causes of chronic gastritis, peptic ulcer disease (PUD), gastric mucosa-associated lymphoid tissue lymphoma (MALT) and gastric carcinoma. H. pylori toxin VacA is responsible for host cell apoptosis, whereas CagA is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8418231a4968d331f916ecc4d118ce
https://pubmed.ncbi.nlm.nih.gov/34959071
https://pubmed.ncbi.nlm.nih.gov/34959071
Autor:
Ankit Jaiswal, Monika Jain, Prashant Kodgire, Meenal Choudhary, Amit Kumar Singh, Anubhav Tamrakar
Publikováno v:
International Reviews of Immunology. 37:37-56
Activation-induced cytidine deaminase (AID), primarily expressed in activated mature B lymphocytes in germinal centers, is the key factor in adaptive immune response against foreign antigens. AID is responsible for producing high-affinity and high-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170fb909082a1267829a3c19958a5184
https://doi.org/10.1080/08830185.2017.1369980
https://doi.org/10.1080/08830185.2017.1369980