Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anu Shah"'
Autor:
Anu Shah, Sezin Dagdeviren, Jordan P. Lewandowski, Angela B. Schmider, Elisabeth M. Ricci-Blair, Niranjana Natarajan, Henna Hundal, Hye Lim Noh, Randall H. Friedline, Charles Vidoudez, Jason K. Kim, Amy J. Wagers, Roy J. Soberman, Richard T. Lee
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101521- (2020)
Summary: Increased consumption of fats and added sugars has been associated with an increase in metabolic syndromes. Here we show that mice chronically fed an energy-rich diet (ERD) with high fat and moderate sucrose have enhanced the absorption of a
Externí odkaz:
https://doaj.org/article/24e910ae67174beba18cf61e73cb6974
Autor:
James R Dotimas, Austin W Lee, Angela B Schmider, Shannon H Carroll, Anu Shah, Julide Bilen, Kayla R Elliott, Ronald B Myers, Roy J Soberman, Jun Yoshioka, Richard T Lee
Publikováno v:
eLife, Vol 5 (2016)
Metabolic studies suggest that the absorptive capacity of the small intestine for fructose is limited, though the molecular mechanisms controlling this process remain unknown. Here we demonstrate that thioredoxin-interacting protein (Txnip), which re
Externí odkaz:
https://doaj.org/article/feec9b69db374cbf80e078c2f6484bd5
Autor:
Anu Shah, Anant Patel
Publikováno v:
Materials Today: Proceedings. 32:740-745
Even though water is abundantly available, the quantity of water available for direct use is very limited. At the another side, the quality of available water is also deteriorating because daily activities of human increase the load of pollutants whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccf405e0df9f02b8cdbbf003056ae7a1
https://doi.org/10.1016/j.matpr.2020.03.473
https://doi.org/10.1016/j.matpr.2020.03.473
Cell-autonomous role of leucine-rich repeat kinase in the protection of dopaminergic neuron survival
Publikováno v:
eLife, Vol 12 (2024)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson’s disease (PD). However, whether LRRK2 mutations cause PD and degeneration of dopaminergic (DA) neurons via a toxic gain-of-function or a loss-of-funct
Externí odkaz:
https://doaj.org/article/fabed0c9954044a7be4f1170eeaaa540
Autor:
Henna Hundal, Hye Lim Noh, Jordan P. Lewandowski, Charles Vidoudez, Randall H. Friedline, Richard T. Lee, Roy J. Soberman, Angela B. Schmider, Niranjana Natarajan, Jason K. Kim, Elisabeth M Ricci-Blair, Amy J. Wagers, Anu Shah, Sezin Dagdeviren
Publikováno v:
iScience
iScience, Vol 23, Iss 9, Pp 101521-(2020)
iScience, Vol 23, Iss 9, Pp 101521-(2020)
Summary Increased consumption of fats and added sugars has been associated with an increase in metabolic syndromes. Here we show that mice chronically fed an energy-rich diet (ERD) with high fat and moderate sucrose have enhanced the absorption of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076ecdda921673aeded818d7a9a11eb
https://doi.org/10.1016/j.isci.2020.101521
https://doi.org/10.1016/j.isci.2020.101521
Autor:
Sezin Dagdeviren, Anu Shah, Sharad Kumar, Marinna Okawa, Mohsen Sarikhani, Veronika Y. Melnik, Richard T. Lee, Natalie J. Foot
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240554eb2e4f14e22bd1fbc598f0b3c3
https://doi.org/10.1096/fasebj.2020.34.s1.05395
https://doi.org/10.1096/fasebj.2020.34.s1.05395
Publikováno v:
Diabetes. 67
Thioredoxin interacting protein (Txnip) has emerged as a key player in nutrient sensing and carbohydrate metabolism. Our lab recently discovered that Txnip binds to the fructose transporters, Glut 2 and Glut 5, to increase the fructose uptake by ente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5aafb344d9f5be844898f925dac8d23
https://doi.org/10.2337/db18-1901-p
https://doi.org/10.2337/db18-1901-p
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f52661e9cb1ff23e0c0647fbd9538e96
https://doi.org/10.1096/fasebj.2018.32.1_supplement.757.2
https://doi.org/10.1096/fasebj.2018.32.1_supplement.757.2
Publikováno v:
Journal of Endocrinology. 225:1-7
Circulating free fatty acids (FFAs) are elevated in obesity and cause insulin resistance. The objective of the current study was to determine whether the antioxidantN-acetyl-l-cysteine (NAC) prevented hepatic and peripheral insulin resistance caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d60efe3ec70b90eddc4c4de1f8e73f
https://doi.org/10.1530/joe-14-0676
https://doi.org/10.1530/joe-14-0676
Publikováno v:
Journal of Biological Chemistry. 288:6835-6848
Thioredoxin-interacting protein (TxNIP) is up-regulated by high glucose and is associated with oxidative stress. It has been implicated in hyperglycemia-induced β-cell dysfunction and apoptosis. As high glucose and oxidative stress mediate diabetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daf4731b3759b00e7a442f14494cc6b
https://doi.org/10.1074/jbc.m112.419101
https://doi.org/10.1074/jbc.m112.419101