Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anu Punn"'
Publikováno v:
Indian Journal of Rheumatology, Vol 18, Iss 1, Pp 35-39 (2023)
Introduction: In children with Systemic Lupus Erythematosus (SLE), autoantibodies are considered as biomarkers for specific organ involvement or tissue damage. Some autoantibodies are used for diagnosis, disease activity, and few for disease characte
Externí odkaz:
https://doaj.org/article/56a6f4a3e49e4825ba45940aa4a05b50
Publikováno v:
Cellular Signalling
The effect of differential signalling by IL-6 and leukaemia inhibitory factor (LIF) which signal by gp130 homodimerisation or LIFRβ/gp130 heterodimerisation on survival and hypertrophy was studied in neonatal rat cardiomyocytes. Both LIF and IL-6 [i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93235a8bbebefd66a650ae6e6d871f46
https://ora.ox.ac.uk/objects/uuid:4e2e7669-ae48-4111-a88e-61438fbd79ad
https://ora.ox.ac.uk/objects/uuid:4e2e7669-ae48-4111-a88e-61438fbd79ad
Autor:
Anu Punn, Jiyou Tang, George Liapakis, Jing Chen, Michael A. Levine, Dimitris K. Grammatopoulos, Maria Delidaki, Hendrik Lehnert
Publikováno v:
The Journal of Biological Chemistry
Background: The CRH-R1 is key for mammalian adaptation to stress; however, the structural determinants of signal transduction are unknown. Results: Amino acids identified within CRH-R1 IC3 appear crucial for G protein-dependent cAMP and ERK1/2 signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12c96769893164a82eca03c0b464e27
http://europepmc.org/articles/PMC3308756
http://europepmc.org/articles/PMC3308756
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(5):896-907
In most target tissues, the adenylyl cyclase/cAMP/PKA, the extracellular signal regulated kinase and the protein kinase B/Akt are the main pathways employed by the type 2 corticotropin-releasing hormone receptor to mediate the biological actions of u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8f26264ce875de61862687f3b56823
Publikováno v:
Cellular Signalling. 20:1651-1661
Orexin-A and orexin-B orchestrate their diverse central and peripheral effects via two G-protein coupled receptors, OX1R and OX2R, which activate multiple G-proteins. In many tissues, orexins activate extracellular signal-regulated kinase (ERK(1/2))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b634e82180878e4e93f114f15ee8a3
https://doi.org/10.1016/j.cellsig.2008.05.010
https://doi.org/10.1016/j.cellsig.2008.05.010
Publikováno v:
Molecular Endocrinology. 22:689-706
Many important physiological roles of the urocortin (UCN) family of peptides as well as CRH involve the type 2 CRH receptor (CRH-R2) and downstream activation of multiple pathways. To characterize molecular determinants of CRH-R2 functional activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8758a978dfceccb2d18fa5df6f602a2
https://doi.org/10.1210/me.2007-0136
https://doi.org/10.1210/me.2007-0136
Publikováno v:
Cardiovascular Research. 78:356-365
Aims Visfatin is a novel adipokine whose plasma concentrations are altered in obesity and obesity-related disorders; these states are associated with an increased incidence of cardiovascular disease. We therefore investigated the effect of visfatin o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6fc6443df408e62296548597af2f9e
https://doi.org/10.1093/cvr/cvm111
https://doi.org/10.1093/cvr/cvm111
Autor:
Gaelle Benais-Pont, Catalina Flores-Maldonado, Maria S. Balda, Tom P. Fleming, Graça Raposo, Marcelino Cereijido, Anu Punn, Karl Matter, Judith J. Eckert
Publikováno v:
The Journal of Cell Biology
Rho family GTPases are important regulators of epithelial tight junctions (TJs); however, little is known about how the GTPases themselves are controlled during TJ assembly and function. We have identified and cloned a canine guanine nucleotide excha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82af11da853d028092743d11e5bf7f3
https://doi.org/10.1083/jcb.200211047
https://doi.org/10.1083/jcb.200211047
Publikováno v:
Indian Journal of Rheumatology, Vol 17, Iss 2, Pp 124-128 (2022)
Objectives: This study aimed to determine whether mycophenolic acid area under the curve 0–12 h (MPA AUC0–12) concentrations correlate with the disease activity in children with lupus nephritis. Methodology: Twenty-five children who fulfilled the
Externí odkaz:
https://doaj.org/article/13603e1ae5fe445080b39eabbdf4ab65
Publikováno v:
Biochemical Journal. 350:891-899
Delayed cytoprotection (preconditioning) occurs 24h after sublethal simulated ischaemia and reperfusion (SI/R) in neonatal rat ventricular cardiomyocytes. SI/R was used to investigate the role of activation of mitogen-activated protein kinases (MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::251d695f2c312718f166a19d6f7f717d
https://doi.org/10.1042/bj3500891
https://doi.org/10.1042/bj3500891