Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anu Pasanen"'
Autor:
Anu Pasanen, Minna K Karjalainen, FinnGen, Ge Zhang, Heli Tiensuu, Antti M Haapalainen, Marja Ojaniemi, Bjarke Feenstra, Bo Jacobsson, Aarno Palotie, Hannele Laivuori, Louis J Muglia, Mika Rämet, Mikko Hallman
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010982 (2023)
BackgroundPreterm birth (MethodsWe conducted a genome-wide meta-analysis of gestational duration and spontaneous preterm birth in 68,732 and 98,370 European mothers, respectively.ResultsThe meta-analysis detected 15 loci associated with gestational d
Externí odkaz:
https://doaj.org/article/f14300073a8b497a870ffbbe353c0e10
Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth
Autor:
Heli Tiensuu, Antti M. Haapalainen, Pinja Tissarinen, Anu Pasanen, Tomi A. Määttä, Johanna M. Huusko, Steffen Ohlmeier, Ulrich Bergmann, Marja Ojaniemi, Louis J. Muglia, Mikko Hallman, Mika Rämet
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Preterm birth is defined as live birth before 37 completed weeks of pregnancy, and it is a major problem worldwide. The molecular mechanisms that lead to onset of spontaneous preterm birth are incompletely understood. Prediction a
Externí odkaz:
https://doaj.org/article/04242490e6fe48ffa80aef8110c60e46
Autor:
Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as m
Externí odkaz:
https://doaj.org/article/f305df8cd6b34e51b15c496289d931fa
Autor:
Silva Kasela, Victor E. Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, Kristina L. Buschur, Igor Z. Barjaktarevic, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Jeffrey L. Curtis, MeiLan K. Han, Nadia N. Hansel, Eric A. Hoffman, Robert J. Kaner, Jerry A. Krishnan, Fernando J. Martinez, Merry-Lynn N. McDonald, Deborah A. Meyers, Robert Paine, Stephen P. Peters, Mario Castro, Loren C. Denlinger, Serpil C. Erzurum, John V. Fahy, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Xingnan Li, Wendy C. Moore, Sally E. Wenzel, Joe Zein, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Charles Langelier, Prescott G. Woodruff, Tuuli Lappalainen, Stephanie A. Christenson
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypot
Externí odkaz:
https://doaj.org/article/87ab72a86e144f1c976576cc59d3efd7
Autor:
Heli Tiensuu, Antti M Haapalainen, Minna K Karjalainen, Anu Pasanen, Johanna M Huusko, Riitta Marttila, Marja Ojaniemi, Louis J Muglia, Mikko Hallman, Mika Rämet
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008107 (2019)
Spontaneous preterm birth (SPTB) is the leading cause of neonatal death and morbidity worldwide. Both maternal and fetal genetic factors likely contribute to SPTB. We performed a genome-wide association study (GWAS) on a population of Finnish origin
Externí odkaz:
https://doaj.org/article/40722b32dea848e9ab80e286121da752
Autor:
Jeffrey C. Murray, Kaare Christensen, Johanna M. Huusko, Ge Zhang, Mika Rämet, Antti M. Haapalainen, Anu Pasanen, Mikko Hallman, Minna K. Karjalainen, Bo Jacobsson, Pinja Tissarinen, Heli Tiensuu, Kelli K. Ryckman, Louis J. Muglia, Stephen F. Kingsmore
Publikováno v:
Scientific Reports
Huusko, J M, Tiensuu, H, Haapalainen, A M, Pasanen, A, Tissarinen, P, Karjalainen, M K, Zhang, G, Christensen, K, Ryckman, K K, Jacobsson, B, Murray, J C, Kingsmore, S F, Hallman, M, Muglia, L J & Rämet, M 2021, ' Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth ', Scientific Reports, vol. 11, 17115 . https://doi.org/10.1038/s41598-021-96374-9
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Huusko, J M, Tiensuu, H, Haapalainen, A M, Pasanen, A, Tissarinen, P, Karjalainen, M K, Zhang, G, Christensen, K, Ryckman, K K, Jacobsson, B, Murray, J C, Kingsmore, S F, Hallman, M, Muglia, L J & Rämet, M 2021, ' Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth ', Scientific Reports, vol. 11, 17115 . https://doi.org/10.1038/s41598-021-96374-9
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as multifunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed011d2f316be5a08f0d88c3400f0a0b
https://hdl.handle.net/11250/2988984
https://hdl.handle.net/11250/2988984
Autor:
Russell P. Bowler, Serpil C. Erzurum, Wendy C. Moore, Robert Paine, Suresh Garudadri, Xingnan Li, Sally E. Wenzel, Prescott G. Woodruff, John V. Fahy, Eric A. Hoffman, Elliot Israel, Jerry A. Krishnan, Loren C. Denlinger, Christopher B. Cooper, Nhlbi SubPopulations, Silva Kasela, Elizabeth J. Ampleford, Tuuli Lappalainen, MeiLan K. Han, Kristina L. Buschur, Charles Langelier, David Couper, Stephanie A. Christenson, Jenna Nguyen, Joe Zein, R. Graham Barr, Molly Martorella, InteRmediate Outcome Measures In Copd Study, Fernando J. Martinez, Nizar N. Jarjour, Srilaxmi Nerella, Jeffrey L. Curtis, Stephen P. Peters, Alejandro P. Comellas, Deborah A. Meyers, Victor E. Ortega, Nadia N. Hansel, Igor Barjaktarevic, Bruce D. Levy, Mario Castro, Gerard J. Criner, Merry-Lynn McDonald, Robert J. Kaner, Eugene R. Bleecker, Anu Pasanen
Publikováno v:
Genome medicine, vol 13, iss 1
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Genome Medicine
Background The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b11fe7cdc9fb2dff006e35e8372031
https://doi.org/10.1101/2020.10.01.20202820
https://doi.org/10.1101/2020.10.01.20202820
Autor:
Johannes Waage, Laura Kummola, Eija Piippo-Savolainen, Klaus Bønnelykke, Marja Ruotsalainen, Nadja Hawwa Vissing, Mika Rämet, Matti Korppi, Bo L. Chawes, Ilkka Junttila, Kirsi Nuolivirta, Mikko Hallman, Anu Pasanen, Hans Bisgaard, Göran Wennergren, Minna K. Karjalainen, Tuomas Jartti, Emma Goksör
Publikováno v:
Pediatric Research. 84:451-457
Genetic factors associated with bronchiolitis are inadequately characterized. We therefore inspected a selected subpopulation of our previous genome-wide association study (GWAS) of bronchiolitis for overlap with known quantitative trait loci (QTLs)
Autor:
Johannes Waage, Astrid Sevelsted, Bo L. Chawes, Matti Korppi, Andrea Heinzmann, Anu Pasanen, Minna K. Karjalainen, Hennie M. Hodemaekers, Hans Bisgaard, Riny Janssen, Göran Wennergren, Anders Husby, Louis Bont, Jakob Stokholm, Klaus Bønnelykke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c50922aeb59e39de714d85b8c04fdf3
https://europepmc.org/articles/PMC5675819/
https://europepmc.org/articles/PMC5675819/