Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anu Muona"'
Autor:
Meike Hedwig Keuters, Velta Keksa-Goldsteine, Hiramani Dhungana, Mikko T. Huuskonen, Yuriy Pomeshchik, Ekaterina Savchenko, Paula K. Korhonen, Yajuvinder Singh, Sara Wojciechowski, Šárka Lehtonen, Katja M. Kanninen, Tarja Malm, Jouni Sirviö, Anu Muona, Milla Koistinaho, Gundars Goldsteins, Jari Koistinaho
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Lipid peroxidation-initiated ferroptosis is an iron-dependent mechanism of programmed cell death taking place in neurological diseases. Here we show that a condensed benzo[b]thiazine derivative small molecule with an arylthiazine backbone (A
Externí odkaz:
https://doaj.org/article/3ca87910b4fe497bb6a795384b53ddb2
Autor:
Meike Hedwig, Keuters, Velta, Keksa-Goldsteine, Hiramani, Dhungana, Mikko T, Huuskonen, Yuriy, Pomeshchik, Ekaterina, Savchenko, Paula K, Korhonen, Yajuvinder, Singh, Sara, Wojciechowski, Šárka, Lehtonen, Katja M, Kanninen, Tarja, Malm, Jouni, Sirviö, Anu, Muona, Milla, Koistinaho, Gundars, Goldsteins, Jari, Koistinaho
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Lipid peroxidation-initiated ferroptosis is an iron-dependent mechanism of programmed cell death taking place in neurological diseases. Here we show that a condensed benzo[b]thiazine derivative small molecule with an arylthiazine backbone (ADA-409-05
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5265710d2c9646d23c080201ac5eaf4a
http://hdl.handle.net/10138/334982
http://hdl.handle.net/10138/334982
Autor:
Karolina Rasi, Mika Kallio, Raija Soininen, Taina Pihlajaniemi, Heikki Tanila, Saara Stavén, Anthony M. Heape, Merja Hurskainen, Pirkko Huhtala, Robin L. Avila, Raija Sormunen, Daniel A. Kirschner, Uolevi Tolonen, Anu Muona
Publikováno v:
The Journal of Neuroscience. 30:14490-14501
Although the Schwann cell basement membrane (BM) is required for normal Schwann cell terminal differentiation, the role of BM-associated collagens in peripheral nerve maturation is poorly understood. Collagen XV is a BM zone component strongly expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953d057b0314305adfd03b5a46fd3548
https://doi.org/10.1523/jneurosci.2644-10.2010
https://doi.org/10.1523/jneurosci.2644-10.2010
Autor:
Lauri Eklund, Naomi Fukai, Ritva Ylikärppä, Bjorn R. Olsen, Raija Sormunen, Anu Muona, Taina Pihlajaniemi
Publikováno v:
Matrix Biology. 22:443-448
Generation of double knockout mice for collagen types XV and XVIII indicated surprisingly that the mice are viable and do not suffer from any new major defects. Although the two collagens are closely related molecules sharing similarities in tissue e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18e4bfe4d1237fcc2888aae24badc27
https://doi.org/10.1016/s0945-053x(03)00074-x
https://doi.org/10.1016/s0945-053x(03)00074-x
Autor:
Heikki Tanila, Milla Koistinaho, Tarja Malm, Anu Muona, Jari Koistinaho, Riikka Heikkinen, Janne Heikkilä
Publikováno v:
Aging and Disease. 5
Cerebral ischemia is a risk factor for Alzheimer's disease (AD). Moreover, recent evidence indicates that it is a two-way street as the incidence rate of stroke is significantly higher in AD patients than those without the disease. Here we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4860e7797c39d71ff7b24320b55cd0
https://doi.org/10.14336/ad.2014.050076
https://doi.org/10.14336/ad.2014.050076
Publikováno v:
Matrix Biology. 19:489-500
Isolation and characterization of the mouse gene for the α1 chain of type XV collagen ( Col15a1 ) revealed it to be approximately 110 kb in length and contain 40 exons. Analysis of the proximal 5′-flanking region showed properties characteristic o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347847c8b10022d4a35d8c1efce86ea8
https://doi.org/10.1016/s0945-053x(00)00090-1
https://doi.org/10.1016/s0945-053x(00)00090-1
Autor:
Ekaterina Savchenko, Jussi Aarnio, Eveliina Pollari, Tarja Malm, Esa Jantunen, Šárka Lehtonen, Piia Valonen, Anu Muona, Milla Koistinaho, Taisia Rolova, Johanna Magga, Petri Lehenkari, Jari Koistinaho
Publikováno v:
Journal of Cellular and Molecular Medicine
Accumulation of amyloid β (Aβ) is a major hallmark in Alzheimer’s disease (AD). Bone marrow derived monocytic cells (BMM) have been shown to reduce Aβ burden in mouse models of AD, alleviating the AD pathology. BMM have been shown to be more eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25de618f1fa6cd5faaf4582584667a72
https://pubmed.ncbi.nlm.nih.gov/21777378
https://pubmed.ncbi.nlm.nih.gov/21777378
Autor:
Milla Koistinaho, Jari Koistinaho, Ekaterina Savchenko, Anu Muona, Malm Tarja, Piia Valonen, Johanna Magga
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65634b6b01fede15856ab5419eb7de66
https://doi.org/10.1016/j.jalz.2011.05.1909
https://doi.org/10.1016/j.jalz.2011.05.1909
Publikováno v:
Glia.
Alzheimer's disease (AD) is a dementing neurodegenerative disorder without a cure. The abnormal parenchymal accumulation of beta-amyloid (Abeta) is associated with inflammatory reactions involving microglia and astrocytes. Increased levels of Abeta a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259d1535f60d1ee5dfbda7ebb33e08de
https://doi.org/10.1002/glia.20973
https://doi.org/10.1002/glia.20973
Autor:
Susanna Kuhmonen, Jari Koistinaho, Riikka Heikkinen, Milla Koistinaho, Toni Ahtoniemi, Heikki Tanila, Anu Muona, Susanna Boman, Tarja Malm
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abfb5480f20cc29d8641ad7c499046bf
https://doi.org/10.1016/j.jalz.2009.04.725
https://doi.org/10.1016/j.jalz.2009.04.725