Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anu Kiviniemi"'
Autor:
Meeri Käkelä, Anne Roivainen, Tiina Saanijoki, Pasi Virta, Anu Kiviniemi, Jussi Mäkilä, Satish Jadhav, Tiina Laitala-Leinonen, Harri Lönnberg, Heidi Liljenbäck, Päivi Poijärvi-Virta
Publikováno v:
Molecular Pharmaceutics
MicroRNAs (miRNAs) are endogenous, small, noncoding ribonucleic acids (RNAs) that bind to the 3′ untranslated regions of messenger RNAs (mRNAs) and induce translational repression or mRNA degradation. Although numerous studies have reported that mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660f8e9aaa5a4c837423471118a58ff2
https://doi.org/10.1021/acs.molpharmaceut.8b01169
https://doi.org/10.1021/acs.molpharmaceut.8b01169
Autor:
Pasi Virta, Satish Jadhav, Meeri Käkelä, Harri Lönnberg, Heidi Liljenbäck, Päivi Poijärvi-Virta, Jussi Mäkilä, Anne Roivainen, Anu Kiviniemi, Tiina Laitala-Leinonen
Publikováno v:
Bioorganic and Medicinal Chemistry. 22(24):6806-6813
68Ga labelled 2′-O-methyl oligoribonucleotides (anti-miR-15b) bearing one, three or seven d -galactopyranoside residues have been prepared and their distribution in healthy rats has been studied by positron emission tomography (PET). To obtain the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afecd3bfc0293e3e7c97579f7eb24a67
https://doi.org/10.1016/j.bmc.2014.10.034
https://doi.org/10.1016/j.bmc.2014.10.034
Publikováno v:
The Journal of Organic Chemistry. 78:5153-5159
Peptide nucleic acid (PNA) building blocks, bearing a fluorine sensor at C-5 of the uracil base [viz. trifluoromethyl and 3,3-bis(trifluoromethyl)-4,4,4-trifluorobut-1-ynyl], were synthesized and incorporated to a PNA strand, and their applicability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55acbcbfa8a8b73b897003f0137ccdfc
https://doi.org/10.1021/jo400014y
https://doi.org/10.1021/jo400014y
Autor:
Harri Lönnberg, Tiina Saanijoki, Tiina Laitala-Leinonen, Anu Kiviniemi, Joonas Mäkelä, Jussi Mäkilä, Pasi Virta, Anne Roivainen, Heidi Liljenbäck, Päivi Poijärvi-Virta
Publikováno v:
Bioconjugate Chemistry. 23(9):1981-1988
Esterified precursors of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA; 18) and 1,4,7-triazacyclononane-1,4,7-trisacetic acid (NOTA; 17,19) ligands bearing a dimethoxytritylated hydroxyl side arm were prepared and immobilized via an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f05ad96b46a5aa3edb6216231b1aac6
http://juuli.fi/Record/0248888912
http://juuli.fi/Record/0248888912
Autor:
Anu Kiviniemi, Pasi Virta
Publikováno v:
Bioconjugate Chemistry. 22:1559-1566
The potential of aminoglycosides to induce RNA-invasion has been demonstrated. For this purpose, aminoglycoside-3'-conjugates of 2'-O-methyl oligoribonucleotides have been synthesized entirely on a solid phase. The synthesis includes an automated oli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1549feab25e2ebf6ed47f856d9c78750
https://doi.org/10.1021/bc200101r
https://doi.org/10.1021/bc200101r
Publikováno v:
Bioconjugate Chemistry. 21:1890-1901
4'-C-[N,N-Di(4-pentyn-1-yl)aminomethyl]thymidine and 4'-C-[N-methyl-N-(4-pentyn-1-yl)aminomethyl]thymidine 3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidites (1, 2) were synthesized, and one or two such monomers were incorporated into a 15-mer oligode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf8f3bed2b6119ce5d1937ca6fb8717
https://doi.org/10.1021/bc100268w
https://doi.org/10.1021/bc100268w
Publikováno v:
Bioconjugate Chemistry. 19:1726-1734
4'-C-Azidomethylthymidine 3'-(H-phosphonate) monomer (10) was synthesized in high yield and three such monomers were incorporated by the H-phosphonate coupling into a 15-mer oligodeoxyribonucleotide. The unmodified 2'-deoxynucleosides could be couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2444b169084fe6c2c95db2e9671678db
https://doi.org/10.1021/bc800221p
https://doi.org/10.1021/bc800221p
Publikováno v:
Open Chemistry, Vol 5, Iss 1, Pp 191-200 (2007)
Five different di-O-alkylated pentaerythritol phosphoramidite building blocks (2a–e) were synthesized and introduced into oligonucleotides to obtain mass-tagged probes (6a–f) useful in RNA transcription profiling. These non-nucleosidic mass tags
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde52ce724b346d728e416d111844caa
https://doaj.org/article/2d1f23818af14f23a4d9ab8c62a16645
https://doaj.org/article/2d1f23818af14f23a4d9ab8c62a16645
Publikováno v:
Tetrahedron: Asymmetry. 15:3723-3729
Burkholderia cepacia lipase-catalyzed acylation with butanoic anhydride was used for the preparation of pharmaceutically important norphenylephrine and octopamine enantiomers, all in 98% ee. Reactivity of the phenolic OH groups and easy racemization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff07c84214c80b27541ed2065ce69b1
https://doi.org/10.1016/j.tetasy.2004.10.027
https://doi.org/10.1016/j.tetasy.2004.10.027
Publikováno v:
Journal of the American Chemical Society. 126:11040-11045
Hydrolytic reactions of guanosyl-(3',3')-uridine and guanosyl-(3',3')-(2',5'-di-O-methyluridine) have been followed by RP HPLC over a wide pH range at 363.2 K in order to elucidate the role of the 2'-hydroxyl group as a hydrogen-bond donor upon depar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09da3deb8d60c87d876e765ca086b94f
https://doi.org/10.1021/ja047568i
https://doi.org/10.1021/ja047568i