Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Anu, Paul"'
Autor:
Tanuja Chitnis, Ferhan Qureshi, Victor M. Gehman, Michael Becich, Riley Bove, Bruce A. C. Cree, Refujia Gomez, Stephen L. Hauser, Roland G. Henry, Amal Katrib, Hrishikesh Lokhande, Anu Paul, Stacy J. Caillier, Adam Santaniello, Neda Sattarnezhad, Shrishti Saxena, Howard Weiner, Hajime Yano, Sergio E. Baranzini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The multifaceted nature of multiple sclerosis requires quantitative biomarkers that can provide insights related to diverse physiological pathways. To this end, proteomic analysis of deeply-phenotyped serum samples, biological pathway modeli
Externí odkaz:
https://doaj.org/article/833d8dd5aeba4eed913b4c923942db14
Autor:
Alicia Gonzalez-Martinez, Rohit Patel, Brian C. Healy, Hrishikesh Lokhande, Anu Paul, Shrishti Saxena, Mariann Polgar-Turcsanyi, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-8 (2023)
Abstract Background Multiple sclerosis (MS) is a disabling autoimmune demyelinating disorder affecting young people and causing significant disability. In the last decade, different microRNA (miRNA) expression patterns have been associated to several
Externí odkaz:
https://doaj.org/article/dc8a9c5060d94362ad72bda2d15d0d9a
Autor:
Kristin Galetta, Chinmay Deshpande, Brian C. Healy, Bonnie Glanz, Marina Ziehn, Shrishti Saxena, Anu Paul, Fermisk Saleh, Mikaela Collins, Patricia Gaitan‐Walsh, Paola Castro‐Mendoza, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 3, Pp 631-638 (2021)
Abstract Objective Serum neurofilament light (sNfL) is a promising new biomarker in multiple sclerosis (MS). We explored the relationship between sNfL and health outcomes and resource use in MS patients. Methods MS patients with serum samples and hea
Externí odkaz:
https://doaj.org/article/4b7c25b42f854aa1a018f07ebfcd118e
Autor:
Felipe von Glehn, Nathalie Pochet, Bibek Thapa, Radhika Raheja, Maria A. Mazzola, Sushrut Jangi, Vanessa Beynon, Junning Huang, Alessandro S. Farias, Anu Paul, Leonilda M. B. Santos, Roopali Gandhi, Gopal Murugaiyan, Howard L. Weiner, Clare M. Baecher-Allan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8000 (2023)
The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become similarly tolerogenic when exposed to IL-27 as this may represent a potential mechanism of au
Externí odkaz:
https://doaj.org/article/bb78a41d9eda4d7dada4997be6b0e2b8
Autor:
Mai Fujiwara, Radhika Raheja, Lucien P. Garo, Amrendra K. Ajay, Ryoko Kadowaki-Saga, Sukrut H. Karandikar, Galina Gabriely, Rajesh Krishnan, Vanessa Beynon, Anu Paul, Amee Patel, Shrishti Saxena, Dan Hu, Brian C. Healy, Tanuja Chitnis, Roopali Gandhi, Howard L. Weiner, Gopal Murugaiyan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
A disequilibrium between immunosuppressive Tregs and inflammatory IL-17–producing Th17 cells is a hallmark of autoimmune diseases, including multiple sclerosis (MS). However, the molecular mechanisms underlying the Treg and Th17 imbalance in CNS au
Externí odkaz:
https://doaj.org/article/f89dcb7cef1c42e89481250a5cdf5db1
Autor:
Mattia Rosso, Cindy T. Gonzalez, Brian C. Healy, Shrishti Saxena, Anu Paul, Kjetil Bjornevik, Jens Kuhle, Pascal Benkert, David Leppert, Charles Guttmann, Rohit Bakshi, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 6, Pp 945-955 (2020)
Abstract Objective Multiple sclerosis (MS) is an autoimmune demyelinating disorder, which is characterized by relapses and remissions. Serum neurofilament light chain (sNfL) is an emerging biomarker of disease activity but its clinical use is still l
Externí odkaz:
https://doaj.org/article/803a62e77ea64fa5b7bb2923000a7e6e
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: There is an emerging evidence of the role of the microbiome in neurological diseases. Endotoxin is a component of gram-negative bacteria and thought to be one of the possible signals between the gut microbiota and the immune system. Previ
Externí odkaz:
https://doaj.org/article/ccdae6e296f64d69ae9e9296fc9994f4
Publikováno v:
Journal of Pediatric Urology. 18:470-476
Correction of penile curvature or "chordee" is a major component in the management of hypospadias. Accurate assessment and management of penile curvature influence both short- and long-term outcomes of surgery.The objective of this study is to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a27f00a9d80eab9360ca91cc579e977
https://doi.org/10.1016/j.jpurol.2022.04.009
https://doi.org/10.1016/j.jpurol.2022.04.009
Autor:
Thais G. Moreira, Christian D. Gauthier, Liam Murphy, Toby B. Lanser, Anu Paul, Kimble T. F. Matos, Davide Mangani, Saef Izzy, Rafael M. Rezende, Brian C. Healy, Clare M. Baecher-Allan, Tanuja Chitnis, Vijay Kuchroo, Howard L. Weiner
Publikováno v:
Proceedings of the National Academy of Sciences. 120
T cells are present in early stages of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and play a major role in disease outcome and long-lasting immunity. Nasal administration of a fully human anti-CD3 monoclonal antibody (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1b76744f81a3b7a9635b47bb99f7ce
https://doi.org/10.1073/pnas.2220272120
https://doi.org/10.1073/pnas.2220272120
Autor:
Ijeoma Nwachukwu, Shimaa Ibrahim, Anu Paul, Massimo Garriboli, Arash Taghizadeh, Brianna Cloke, Narayan Karunanithy, Pankaj Mishra
Publikováno v:
Journal of Pediatric Endoscopic Surgery. 4:133-136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4b0a4b7a5871785cd32437acc1ee7c
https://doi.org/10.1007/s42804-022-00142-z
https://doi.org/10.1007/s42804-022-00142-z