Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Antu K. Dey"'
Autor:
Anannya Bhattacharya, Lonzaric Jan, Olga Burlak, Jilong Li, Ghanshyam Upadhyay, Katherine Williams, Jinhui Dong, Harrison Rohrer, Michelle Pynn, Andrew Simon, Nathan Kuhlmann, Sergei Pustylnikov, Mariane B. Melo, Antu K. Dey
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Varicella zoster virus (VZV) is a highly contagious human herpes virus responsible for causing chickenpox (varicella) and shingles (herpes zoster). Despite the approval of a highly effective vaccine, Shingrix®, the global incidence of herpe
Externí odkaz:
https://doaj.org/article/275e736cb31442479d18b298d31e253b
Autor:
Felipe Lelis, Laura A. Byk, Sergei Pustylnikov, Vivian Nguyen, Brandon Nguyen, Malorie Nitz, Prutha Tarte, Kunal Tungare, Jilong Li, Saikat Manna, Sampa Maiti, Dhwani H. Mehta, Narendran Sekar, Diana M. Posadas, Himanshu Dhamankar, Jeffrey A. Hughes, Lorenzo Aulisa, Amin Khan, Mariane B. Melo, Antu K. Dey
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Several COVID-19 vaccines, some more efficacious than others, are now available and deployed, including multiple mRNA- and viral vector-based vaccines. With the focus on creating cost-effective solutions that can reach the low- and medium- i
Externí odkaz:
https://doaj.org/article/5cd8b9585ddd48ba870d45a8620ef89e
Autor:
Anannya Bhattacharya, Lonzaric Jan, Olga Burlak, Jilong Li, Ghanshyam Upadhyay, Katherine Williams, Jinhui Dong, Harrison Rohrer, Michelle Pynn, Andrew Simon, Nathan Kuhlmann, Sergei Pustylnikov, Mariane B. Melo, Antu K. Dey
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4517f36fd122404ab2f07ac71cf7002c
Autor:
Tysheena P Charles, Samantha L Burton, Prabhu S Arunachalam, Christopher A Cottrell, Leigh M Sewall, Venkata S Bollimpelli, Sailaja Gangadhara, Antu K Dey, Andrew B Ward, George M Shaw, Eric Hunter, Rama R Amara, Bali Pulendran, Marit J van Gils, Cynthia A Derdeyn
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009257 (2021)
Stabilized HIV-1 envelope (Env) trimers elicit tier 2 autologous neutralizing antibody (nAb) responses in immunized animals. We previously demonstrated that BG505 SOSIP.664.T332N gp140 (BG505 SOSIP) immunization of rhesus macaques (RM) provided robus
Externí odkaz:
https://doaj.org/article/9eebb505e6de4f35a7e3bc5ad081b207
Autor:
Vaneet K. Sharma, Bijay Misra, Kevin T. McManus, Sreenivas Avula, Kaliappanadar Nellaiappan, Marina Caskey, Jill Horowitz, Michel C. Nussenzweig, Michael S. Seaman, Indu Javeri, Antu K. Dey
Publikováno v:
Antibodies, Vol 9, Iss 3, p 36 (2020)
The discovery of numerous potent and broad neutralizing antibodies (bNAbs) against Human Immunodeficiency Virus type 1 (HIV-1) envelope glycoprotein has invigorated the potential of using them as an effective preventative and therapeutic agent. The m
Externí odkaz:
https://doaj.org/article/dfdf1d2826e045a4ba960b0d2c10ab6c
Autor:
Nathifa Moyo, Edmund G. Wee, Bette Korber, Kapil Bahl, Samantha Falcone, Sunny Himansu, Adrianne L. Wong, Antu K. Dey, Mark Feinberg, Tomáš Hanke
Publikováno v:
Vaccines, Vol 8, Iss 3, p 360 (2020)
A vaccine will likely be one of the key tools for ending the HIV-1/AIDS epidemic by preventing HIV-1 spread within uninfected populations and achieving a cure for people living with HIV-1. The currently prevailing view of the vaccine field is to intr
Externí odkaz:
https://doaj.org/article/c6a3f4acd94640fab6a5e393110fa76d
Autor:
Carlo Zambonelli, Antu K Dey, Susan Hilt, Samuel Stephenson, Eden P Go, Daniel F Clark, Mark Wininger, Celia Labranche, David Montefiori, Hua-Xin Liao, Ronald I Swanstrom, Heather Desaire, Barton F Haynes, Andrea Carfi, Susan W Barnett
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157391 (2016)
The viral envelope glycoprotein (Env) is the major target for antibody (Ab)-mediated vaccine development against the Human Immunodeficiency Virus type 1 (HIV-1). Although several recombinant Env antigens have been evaluated in clinical trials, only t
Externí odkaz:
https://doaj.org/article/3bd711cd04e04af68ea0083b32fc53a5
Autor:
Antu K. Dey, Angela Lim, Jessica P. Dawson, Adin Ross-Gillespie, Mara Rossi, Mirva Hejjaoui Simoneau, Cyril Boucher, Wolf Palinsky, Mark B. Feinberg, Joseph G. Jardine, Bernhard Valldorf, Hervé Broly, Dennis R. Burton, Thomas Hassell, Philippe Dupraz, Rita Agostinetto, Devin Sok
Publikováno v:
Biotechnology and Bioengineering
Therapeutic proteins, including monoclonal antibodies, are typically manufactured using clonally‐derived, stable host cell lines, since consistent and predictable cell culture performance is highly desirable. However, selecting and preparing banks
Autor:
Russell Vassell, Yong He, Prasad Vennakalanti, Antu K Dey, Min Zhuang, Wei Wang, Yide Sun, Zohar Biron-Sorek, Indresh K Srivastava, Celia C LaBranche, David C Montefiori, Susan W Barnett, Carol D Weiss
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128562 (2015)
The membrane proximal external region (MPER) of the gp41 subunit of the HIV-1 envelope glycoprotein (Env) contains determinants for broadly neutralizing antibodies and has remained an important focus of vaccine design. However, creating an immunogen
Externí odkaz:
https://doaj.org/article/2dbc550b61bf4314aa375f1a7113ff50
Autor:
Jian Xiong, Andrew B. Ward, Max Medina-Ramírez, John M. Hickey, Wen-Hsin Lee, Sangeeta B. Joshi, Neal Whitaker, Albert Cupo, Gabriel Ozorowski, Antu K. Dey, Nishant Sawant, John P. Moore, Rogier W. Sanders, David B. Volkin, Kawaljit Kaur
Publikováno v:
Journal of Pharmaceutical Sciences
Journal of pharmaceutical sciences, 108(7), 2264-2277. John Wiley and Sons Inc.
Journal of pharmaceutical sciences, 108(7), 2264-2277. John Wiley and Sons Inc.
The induction of broadly neutralizing antibodies (bNAbs) is a major goal in the development of an effective vaccine against HIV-1. A soluble, trimeric, germline (gI) bNAb-targeting variant of the HIV-1 envelope glycoprotein (termed BG505 SOSIP.v4.1-G