Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ants Kask"'
Autor:
Riina Häidkind, Marika Eller, Jaanus Harro, Lars Oreland, Ago Rinken, Maarike Harro, Ants Kask
Publikováno v:
European Neuropsychopharmacology. 13:19-28
It has been proposed that lesions of the ascending noradrenergic projections render animals more vulnerable to stress. In this study, the effects of partial denervation of the locus coeruleus (LC) by DSP-4 (10 mg/kg) treatment, chronic mild stress (C
Autor:
Ants Kask, Erika Roman, Petri Hyytiä, Helgi B. Schiöth, Karolina Ploj, Jarl E. S. Wikberg, Ingrid Nylander
Publikováno v:
Brain Research Bulletin. 59:97-104
Melanocortin (MC) peptides are suggested to play a role in opiate dependence, where they antagonise the addictive properties of opiates. To further study the involvement of the MCs in drug dependence, we analysed the effects of the MC(4)-receptor ant
Publikováno v:
Journal of Chromatography B. 769:145-153
A novel and simple method has been developed for the simultaneous quantification of tryptophan, kynurenine and indole derivatives as well as four catecholamines, including dopamine, noradrenaline, homovanillic acid and 3,4-dihydroxyphenylacetic acid.
Publikováno v:
Physiology & Behavior. 74:277-282
The rat social interaction (SI) test is used widely to measure anxiety-like behavior, yet the influence of various factors such as testing time, pre-experimental manipulations (transport stress), and testing of animals from the same cage (cohort remo
Publikováno v:
Brain Research. 899:227-239
Chronic variable stress (CVS) and manipulations of 5-HT-ergic neurotransmission are increasingly used as animal models of depression. In the present study, CVS for 2 weeks and a partial lesion of 5-HT projections by a small dose of parachloroamphetam
Publikováno v:
Pharmacology Biochemistry and Behavior. 65:737-742
Present experiments were designed to compare the effects of antidepressants desipramine (10 and 20 mg/kg IP) and fluoxetine (5 and 10 mg/kg IP) with anxiogenic beta-carboline DMCM (0.5 and 1.0 mg/kg IP) in the elevated zero-maze test in rats. The sec
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:143-149
Neuropeptide Y (NPY) and melanocortin (MC) peptides have opposite effects on food intake: NPY-like peptides and MC receptor antagonists stimulate feeding and increase body weight, whereas melanocortins and NPY antagonists inhibit food intake. In this
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:143-149
Autor:
Ilze Mutule, Lembit Rägo, Helgi B. Schiöth, Jarl E. S. Wikberg, Felikss Mutulis, Ants Kask, Rein Pähkla, Ruta Muceniece
Publikováno v:
Endocrinology. 139:5006-5014
Several novel cyclic MSH analogs were synthesized, and their binding properties were tested on cells transiently expressing the human melanocortin-1 (MC1), MC3, MC4, and MC5 receptors. We discovered a novel substance (HS024) that showed about 20-fold
Publikováno v:
Europe PubMed Central
WE have reported previously that the NPY Y 1 receptor antagonist BIBP3226 applied into the dorsal periaqueductal gray matter (DPAG) has an anxiogenic-like effect in the elevated plus-maze test in rats. In the present study the effects of neuropeptide