Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Antrix Jain"'
Autor:
Caishang Zheng, Yanjun Wei, Peng Zhang, Longyong Xu, Zhenzhen Zhang, Kangyu Lin, Jiakai Hou, Xiangdong Lv, Yao Ding, Yulun Chiu, Antrix Jain, Nelufa Islam, Anna Malovannaya, Yun Wu, Feng Ding, Han Xu, Ming Sun, Xi Chen, Yiwen Chen
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
Emerging evidence suggests that cryptic translation within long noncoding RNAs (lncRNAs) may produce novel proteins with important developmental/physiological functions. However, the role of this cryptic translation in complex diseases (e.g., cancer)
Externí odkaz:
https://doaj.org/article/3c21a858f3124ba098252e8992e91b5c
Autor:
Derek L. Reznik, Mingxiao V. Yang, Pedro Albelda de la Haza, Antrix Jain, Melanie Spanjaard, Susanne Theiss, Christian P. Schaaf, Anna Malovannaya, Theresa V. Strong, Surabi Veeraragavan, Rodney C. Samaco
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/79466f972a5047ff8794b4cf8832cc73
Autor:
Duy T. Le, Marcus A. Florez, Pawel Kus, Brandon T. Tran, Bailee Kain, Yingmin Zhu, Kurt Christensen, Antrix Jain, Anna Malovannaya, Katherine Y. King
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106059- (2023)
Summary: Basic leucine zipper ATF-like transcription factor 2 (BATF2), an interferon-activated immune response regulator, is a key factor responsible for myeloid differentiation and depletion of HSC during chronic infection. To delineate the mechanis
Externí odkaz:
https://doaj.org/article/e0f2acdc911f4e5bae8d8d550d626801
Autor:
Tattym E. Shaiken, Sandra L. Grimm, Mohamad Siam, Amanda Williams, Abdol-Hossein Rezaeian, Daniel Kraushaar, Emily Ricco, Matthew J. Robertson, Cristian Coarfa, Antrix Jain, Anna Malovannaya, Fabio Stossi, Antone R. Opekun, Alyssa P. Price, Julien Dubrulle
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105965- (2023)
Summary: Despite the knowledge that protein translation and various metabolic reactions that create and sustain cellular life occur in the cytoplasm, the structural organization within the cytoplasm remains unclear. Recent models indicate that cytopl
Externí odkaz:
https://doaj.org/article/f9e71643635c4025b44b5b347560559c
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Lillian Thistlethwaite, Alaina N. Lewis, Christina Sallas, Ramakrishnan R. Srinivasan, Jonathan T. Lei, Vladimir Kovacevic, Predrag Obradovic, Matthew J. Ellis, C. Kent Osborne, Mothaffar F. Rimawi, Anne Pavlick, Maryam Nemati Shafaee, Heidi Dowst, Antrix Jain, Alexander B. Saltzman, Anna Malovannaya, Elisabetta Marangoni, Alana L. Welm, Bryan E. Welm, Shunqiang Li, Gerburg M. Wulf, Olmo Sonzogni, Chen Huang, Suhas Vasaikar, Susan G. Hilsenbeck, Bing Zhang, Aleksandar Milosavljevic, Michael T. Lewis
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105799- (2023)
Summary: Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive pat
Externí odkaz:
https://doaj.org/article/2b0f86504c374089a6c4e5c09a09e1cb
Autor:
Gianfranco Matrone, Sung Yun Jung, Jong Min Choi, Antrix Jain, Hon-Chiu Eastwood Leung, Kimal Rajapakshe, Cristian Coarfa, Julie Rodor, Martin A. Denvir, Andrew H. Baker, John P. Cooke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The role of the post-translational modifications in tissue regeneration is still not clearly understood. Here, the authors show that many nuclear proteins change S-nitrosylation state in the regenerating zebrafish tailfin, highlighting the importance
Externí odkaz:
https://doaj.org/article/adfe028e44264c2b8db2eceb6959bc23
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010894 (2022)
Streptococcus gallolyticus subspecies gallolyticus (Sgg) has a strong clinical association with colorectal cancer (CRC) and actively promotes the development of colon tumors. Previous work showed that this organism stimulates CRC cells proliferation
Externí odkaz:
https://doaj.org/article/a417565c10b6486d84b5f2335931e7f3
Autor:
Ayse L. Mindikoglu, Mustafa M. Abdulsada, Antrix Jain, Prasun K. Jalal, Sridevi Devaraj, Zoe R. Wilhelm, Antone R. Opekun, Sung Yun Jung
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Metabolic syndrome is characterized by central obesity, insulin resistance, elevated blood pressure, and dyslipidemia. Metabolic syndrome is a significant risk factor for several common cancers (e.g., liver, colorectal, breast, pancreas). Ph
Externí odkaz:
https://doaj.org/article/096ec80f4d2c41b0951e11851e6fe471
Autor:
Xiang Chen, Justin M. M. Cates, Yu-Chen Du, Antrix Jain, Sung Yun Jung, Xiao-Nan Li, John M. Hicks, Tsz‐Kwong Man
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 846-864 (2020)
The development of pulmonary metastasis is the leading cause of death in osteosarcoma (OS), which is the most common malignant bone tumor in children. We have previously reported that the tumor suppressor p27 (KIP1, CDKN1B) is frequently mislocalized
Externí odkaz:
https://doaj.org/article/abe8194521a84310b6dd257de637971c
Autor:
Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Publikováno v:
Cancer Research. 83:P2-23
Background: Triple-negative breast cancer (TNBC) patients frequently receive combination chemotherapy treatment, but a direct comparison of response to carboplatin, docetaxel, and their combination in 50 TNBC patient-derived xenografts (PDXs) showed