Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Antoun El Chemaly"'
Autor:
Francis Rousset, Vivianne B. C. Kokje, Rebecca Sipione, Dominik Schmidbauer, German Nacher-Soler, Sten Ilmjärv, Marta Coelho, Stefan Fink, François Voruz, Antoun El Chemaly, Antoine Marteyn, Hubert Löwenheim, Karl-Heinz Krause, Marcus Müller, Rudolf Glückert, Pascal Senn
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Nearly 460 million individuals are affected by sensorineural hearing loss (SNHL), one of the most common human sensory disorders. In mammals, hearing loss is permanent due to the lack of efficient regenerative capacity of the sensory epithelia and sp
Externí odkaz:
https://doaj.org/article/c641ab44f8a34edeafa6d15a020cc3ac
Autor:
Nicolas Demaurex, Antoun El Chemaly
Publikováno v:
Molecular and cellular endocrinology
Molecular and Cellular Endocrinology, Vol. 353, No 1-2 (2012) pp. 82-7
Molecular and Cellular Endocrinology, Vol. 353, No 1-2 (2012) pp. 82-7
Recent work on animal models has revealed the important role played by the voltage-gated proton channel Hv1 during bacterial killing by innate immune cells. Studies from mice lacking Hv1 channels showed that Hv1 proton channels are required for high-
Autor:
Antoun El Chemaly, Pierre Hoffmeyer, Nicolas Demaurex, Panayiotis Christofilopoulos, Louis Bernard, Samira Daou
Publikováno v:
Biomaterials
Biomaterials, Vol. 32, No 7 (2011) pp. 1769-77
Biomaterials, Vol. 32, No 7 (2011) pp. 1769-77
Infection by Staphylococcus epidermidis is a devastating complication of metal-on-metal (MM) total hip arthroplasty (THA). Neutrophils are the first line of defense against infection, and these innate immune cells are potentially exposed to Co(2+) io
Autor:
Nicolas Demaurex, Antoun El Chemaly
Publikováno v:
The Journal of Physiology. 588:4659-4665
Voltage-gated proton channels are designed to extrude large quantities of cytosolic acid in response to depolarising voltages. The discovery of the Hvcn1 gene and the generation of mice lacking the channel molecule have confirmed several postulated f
Autor:
Antoun El Chemaly, Serge Arnaudeau, Mari Sasaki, Yoshifumi Okochi, Nicolas Demaurex, Yasushi Okamura
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 207, No 1 (2010) pp. 129-139
Journal of Experimental Medicine, Vol. 207, No 1 (2010) pp. 129-139
Neutrophils kill microbes with reactive oxygen species generated by the NADPH oxidase, an enzyme which moves electrons across membranes. Voltage-gated proton channels (voltage-sensing domain only protein [VSOP]/Hv1) are required for high-level supero
Autor:
Victor A. Jebara, Romain Guinamard, Patrick Bois, Jean-François Faivre, Antoun El Chemaly, Nassim Fares, Marie Demion
Publikováno v:
Biochemical and Biophysical Research Communications. 340:512-516
A voltage-activated proton current in human cardiac fibroblasts, measured using the whole-cell recording configuration of the patch-clamp technique, is reported. Increasing the pH of the bathing solution shifted the current activation threshold to mo
Publikováno v:
Journal of Cardiovascular Electrophysiology. 17:60-68
ORCC in Human Atrial Cardiomyocytes. Introduction: Among a range of chloride channels, outwardly rectifying Cl- channels have been reported in the heart of various species. Although the anionic current carried by this channel has been subjected to in
Autor:
Patrick Bois, Antoun El Chemaly, Barbara Renaudon, Jocelyn Bescond, Marie Demion, Aurélien Chatelier
Publikováno v:
European Journal of Pharmacology. 521:29-33
As reported for cyclic nucleotide-gated channels in sensory neurons, we investigated the action of Ca 2+ –calmodulin and calmodulin antagonist (W7) on the apparent affinity of pacemaker ( I f ) channels for cAMP. In this study, we used the patch-cl
Autor:
Jean-François Faivre, Patrick Bois, Christophe Magaud, Nassim Fares, Jocelyn Bescond, Christophe Jayle, Ian Findlay, Antoun El Chemaly, Aurélien Chatelier, Frédéric Becq, Caroline Norez
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2014, 68, pp.12-9. ⟨10.1016/j.yjmcc.2013.12.027⟩
Journal of Molecular and Cellular Cardiology, Elsevier, 2014, 68, pp.12-9. ⟨10.1016/j.yjmcc.2013.12.027⟩
International audience; Cardiac fibroblasts are an integral part of the myocardial tissue and contribute to its remodelling. This study characterises for the first time the calcium-dependent chloride channels (CaCC) in the plasma membrane of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7614ce607cd54b912ceb1672050fc007
https://hal.archives-ouvertes.fr/hal-00990329
https://hal.archives-ouvertes.fr/hal-00990329
Publikováno v:
Biophysical Journal. 106(2)
Cardiac fibroblasts are an integral part of the myocardial tissue and contribute to its remodelling. This study characterizes for the first time the calcium-dependent chloride channels (CaCC) in the plasma membrane of primary human atrial cardiac fib