Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Antos Shakhbazau"'
Autor:
Jacob Daniel de Villiers Alant, Ferry Senjaya, Aleksandra Ivanovic, Joanne Forden, Antos Shakhbazau, Rajiv Midha
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82546 (2013)
Peripheral nerve transection and neuroma-in-continuity injuries are associated with permanent functional deficits, often despite successful end-organ reinnervation. Axonal misdirection with non-specific reinnervation, frustrated regeneration and axon
Externí odkaz:
https://doaj.org/article/56a7a5bad1364580a67b977a7c4b3c62
Publikováno v:
Molecular Biology Reports. 46:1343-1348
Radiation induces DNA and protein damage and free radical formation, effectively establishing cellular senescence in a variety of models. We demonstrate the effects of two known pleiotropic drugs following gamma radiation damage in neurosphere/cerebr
Autor:
M. P. Potapnev, Antos Shakhbazau
Publikováno v:
Cytotherapy. 18:1245-1255
Stem cell therapy for incurable central nervous system disorders has long been viewed as a promising therapeutic option. In this review, we discuss the existing data and approaches on cell transplantation in the context of the neural differentiation
Autor:
V. Wee Yong, Jan van Minnen, Roel Klaver, Jeroen J. G. Geurts, Geert J. Schenk, Jean Kawasoe, Antos Shakhbazau, Curtis M. Hay
Publikováno v:
Shakhbazau, A, Schenk, G J, Hay, C, Kawasoe, J, Klaver, R, Yong, V W, Geurts, J J G & van Minnen, J 2016, ' Demyelination induces transport of ribosome-containing vesicles from glia to axons: evidence from animal models and MS patient brains ', Molecular Biology Reports, vol. 43, no. 6, pp. 495-507 . https://doi.org/10.1007/s11033-016-3990-2
Molecular Biology Reports, 43(6), 495-507. Springer Netherlands
Molecular Biology Reports, 43(6), 495-507. Springer Netherlands
Glial cells were previously proven capable of trafficking polyribosomes to injured axons. However, the occurrence of such transfer in the general pathological context, such as demyelination-related diseases, needs further evidence. Since this may be
Autor:
Tylor Walsh, Antos Shakhbazau, Rajiv Midha, Leila Mirfeizi, Holly M. Wobma, Bhagat Singh, Michael S. Kallos, Ranjan Kumar
Publikováno v:
Biotechnology and Bioengineering. 113:393-402
Emerging bioreactor technologies offer an effective way for scaled-up production of large numbers of cells for cell therapy applications. One of the clinical paradigms where cell therapy can be an asset is restorative neurosciences. Nerve repair can
Autor:
Dzmitry Shcharbin, Craig Brideau, Antos Shakhbazau, Serge Mignani, Maria Bryszewska, Shigeki Tsutsui, Tak-Ho Chu, Manoj Kumar Mishra, Jan van Minnen, Jean-Pierre Majoral, Peter K. Stys, V. Wee Yong, Karen Cummins, Mireille Blanchard-Desce
Publikováno v:
Macromolecular Bioscience. 15:1523-1534
Dendrimers and dendriplexes, highly branched synthetic macromolecules, have gained popularity as new tools for a variety of nanomedicine strategies due to their unique structure and properties. We show that fluorescent phosphorus dendrimers are well
Publikováno v:
Journal of Neurosurgery. 121:423-431
Object Cell therapy is a promising candidate among biological or technological innovations sought to augment microsurgical techniques in peripheral nerve repair. This report describes long-term functional regenerative effects of cell therapy in the r
Autor:
Joey Grochmal, Aleksandra Ivanovic, Rajiv Midha, Ranjan Kumar, Joanne Forden, Jeff Biernaskie, Ferry Senjaya, Aubrey A. Webb, Antos Shakhbazau, Hélène T. Khuong
Publikováno v:
Experimental Neurology. 254:168-179
Previous work has shown that infusion of skin-derived precursors pre-differentiated into Schwann cells (SKP-SCs) can remyelinate injured and regenerating axons, and improve indices of axonal regeneration and electrophysiological parameters in rodents
Publikováno v:
Expert Opinion on Drug Delivery. 10:1687-1698
Gene therapy is one of the most effective ways to treat major infectious diseases, cancer and genetic disorders. It is based on several viral and non-viral systems for nucleic acid delivery. The number of clinical trials based on application of non-v
Autor:
Volha Dzmitruk, Elena Fuentes, Elzbieta Pedziwiatr-Werbicka, María Ángeles Muñoz-Fernández, Rafael Gomez-Ramirez, Elizaveta Drozd, Francisco Javier de la Mata, Dzmitry Shcharbin, Maria Bryszewska, Antos Shakhbazau, Javier Sánchez-Nieves, Marharyta Sudas
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 109:183-189
Treatment of HIV infection by gene therapy is a promising tool for combating AIDS. One of the primary limitations of gene therapy is the effective delivery of nucleic acids to the target cells. Dendrimers are nanoparticles that are increasingly being