Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Antoon J. M. Ligtenberg"'
Publikováno v:
Diagnostics, Vol 6, Iss 4, p 40 (2016)
A common experience after exercise is the presence of a thick and sticky saliva layer on the oral surfaces, which causes a feeling of a dry mouth. Since the salivary mucin MUC5B is responsible for the visco-elastic behavior of saliva, in the present
Externí odkaz:
https://doaj.org/article/862bcd49e8cd40129a5ae7e7a1ba4eba
Publikováno v:
Biochemistry and Cell Biology, 99(1), 128-137. National Research Council of Canada
Ligtenberg, A J M, Bikker, F J & Bolscher, J G M 2021, ' Lfchimera : A synthetic mimic of the two antimicrobial domains of bovine lactoferrin ', Biochemistry and Cell Biology, vol. 99, no. 1, pp. 128-137 . https://doi.org/10.1139/bcb-2020-0285
Ligtenberg, A J M, Bikker, F J & Bolscher, J G M 2021, ' Lfchimera : A synthetic mimic of the two antimicrobial domains of bovine lactoferrin ', Biochemistry and Cell Biology, vol. 99, no. 1, pp. 128-137 . https://doi.org/10.1139/bcb-2020-0285
© The author(s) or their institution(s).Saliva is essential for the maintenance of oral health. When salivary flow is impaired, the risk of various oral diseases such as caries and candidiasis increases drastically. Under healthy conditions, saliva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a5c4b57dcb9290114dee5bbb9472e
https://doi.org/10.1139/bcb-2020-0285
https://doi.org/10.1139/bcb-2020-0285
Autor:
Bruno G. Loos, Antoon J. M. Ligtenberg, Enno C. I. Veerman, Sabrina T.G. Gunput, Patrick Rijkschroeff, Elena A. Nicu
Publikováno v:
Rijkschroeff, P, Gunput, S T G, Ligtenberg, A J M, Veerman, E C I, Loos, B G & Nicu, E A 2018, ' Polymorphonuclear neutrophil integrity and functionality are preserved when exposed to saliva ', Archives of Oral Biology, vol. 92, pp. 68-74 . https://doi.org/10.1016/j.archoralbio.2018.04.019
Archives of Oral Biology, 92, 68-74. Elsevier
Archives of Oral Biology, 92, 68-74. Elsevier Limited
Archives of Oral Biology, 92, 68-74. Elsevier
Archives of Oral Biology, 92, 68-74. Elsevier Limited
Objective Polymorphonuclear neutrophils (PMNs) are the most abundant innate immune cells and are also important effectors in the maintenance of oral health. However, little is known about the effects of saliva on the PMN. We therefore aimed to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2de775c332e12516602e644cd52bbec
https://doi.org/10.1016/j.archoralbio.2018.04.019
https://doi.org/10.1016/j.archoralbio.2018.04.019
Autor:
Jan G. M. Bolscher, Petra A. M. van den Keijbus, Enno C. I. Veerman, Floris J. Bikker, Kamran Nazmi, Antoon J. M. Ligtenberg, Tjitske Sijbrandij
Publikováno v:
Biometals
BioMetals, 31(6), 941-950. Springer Netherlands
Sijbrandij, T, Ligtenberg, A J, Nazmi, K, van den Keijbus, P A M, Veerman, E C I, Bolscher, J G M & Bikker, F J 2018, ' LFchimera protects HeLa cells from invasion by Yersinia spp. in vitro ', BioMetals, vol. 31, no. 6, pp. 941-950 . https://doi.org/10.1007/s10534-018-0136-0
BioMetals, 31(6), 941-950. Springer Netherlands
Sijbrandij, T, Ligtenberg, A J, Nazmi, K, van den Keijbus, P A M, Veerman, E C I, Bolscher, J G M & Bikker, F J 2018, ' LFchimera protects HeLa cells from invasion by Yersinia spp. in vitro ', BioMetals, vol. 31, no. 6, pp. 941-950 . https://doi.org/10.1007/s10534-018-0136-0
Yersinia pestis is the causative agent of plague. As adequate antibiotic treatment falls short and currently no effective vaccine is available, alternative therapeutic strategies are needed. In order to contribute to solving this problem we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16521686c856f76fa202a727a7182d7
http://europepmc.org/articles/PMC6245033
http://europepmc.org/articles/PMC6245033
Autor:
Jan Mollenhauer, Enno C. I. Veerman, Floris J. Bikker, Caroline End, Kamran Nazmi, Rainer Wittig, Antoon J. M. Ligtenberg, Marcus Renner, Stefan Lyer, Arie V. Nieuw Amerongen, Stephanie Blaich, Annemarie Poustka
Publikováno v:
Immunogenetics
Bikker, F J, End, C, Ligtenberg, A J M, Blaich, S, Lyer, S, Renner, M, Wittig, R, Nazmi, K, van Nieuw Amerongen, A, Poustka, A, Veerman, E C I & Mollenhauer, J 2017, ' The scavenging capacity of DMBT1 is impaired by germline deletions ', Immunogenetics, vol. 69, no. 6, pp. 401-407 . https://doi.org/10.1007/s00251-017-0982-x
Immunogenetics, 69(6), 401-407. Springer Verlag
Bikker, F J, End, C, Ligtenberg, A J M, Blaich, S, Lyer, S, Renner, M, Wittig, R, Nazmi, K, van Nieuw Amerongen, A, Poustka, A, Veerman, E C I & Mollenhauer, J 2017, ' The scavenging capacity of DMBT1 is impaired by germline deletions ', Immunogenetics, vol. 69, no. 6, pp. 401-407 . https://doi.org/10.1007/s00251-017-0982-x
Immunogenetics, 69(6), 401-407. Springer Verlag
The Scavenger Receptor Cysteine-Rich (SRCR) proteins are an archaic group of proteins characterized by the presence of multiple SRCR domains. They are membrane-bound or secreted proteins, which are generally related to host defense systems in animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8285d0e1d74a9113ceed1eb9c69d1cc4
https://doi.org/10.1007/s00251-017-0982-x
https://doi.org/10.1007/s00251-017-0982-x
Autor:
Kamran Nazmi, Jingmei Yang, Yafei Wu, Antoon J. M. Ligtenberg, Wim Crielaard, Dongmei Deng, Bernd W. Brandt
Publikováno v:
Scientific Reports, 9(1):19943. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Yang, J, Deng, D, Brandt, B W, Nazmi, K, Wu, Y, Crielaard, W & Ligtenberg, A J M 2019, ' Diversity of SpaP in genetic and salivary agglutinin mediated adherence among Streptococcus mutans strains ', Scientific Reports, vol. 9, no. 1, 19943 . https://doi.org/10.1038/s41598-019-56486-9
Scientific Reports. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Yang, J, Deng, D, Brandt, B W, Nazmi, K, Wu, Y, Crielaard, W & Ligtenberg, A J M 2019, ' Diversity of SpaP in genetic and salivary agglutinin mediated adherence among Streptococcus mutans strains ', Scientific Reports, vol. 9, no. 1, 19943 . https://doi.org/10.1038/s41598-019-56486-9
Scientific Reports. Nature Publishing Group
Scientific Reports
Streptococcus mutans SpaP mediates the binding of this cariogenic bacteria to tooth surfaces. It was reported that the SpaP of S. mutans clinical isolates could be classified to 2 genotypes, type A and B. Our aims are to examine spaP genotypes in oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953b6449133a995fca07a682976d4665
https://hdl.handle.net/1871.1/5cafa836-fce1-414b-aa73-d6deedf148c0
https://hdl.handle.net/1871.1/5cafa836-fce1-414b-aa73-d6deedf148c0
Autor:
Sabrina T.G. Gunput, Antoon J. M. Ligtenberg, Bas Terlouw, Enno C. I. Veerman, Mieke C. Brouwer, Diana Wouters
Publikováno v:
Biological Chemistry, 396(1), 35-43. Walter de Gruyter GmbH
Gunput, S T G, Ligtenberg, A J M, Terlouw, B, Brouwer, M, Veerman, E C I & Wouters, D 2015, ' Complement activation by salivary agglutinin is secretor status dependent ', Biological Chemistry, vol. 396, no. 1, pp. 35-43 . https://doi.org/10.1515/hsz-2014-0200
Biological chemistry, 396(1), 35-43. De Gruyter
Biological chemistry, 396(1), 35-43. Walter de Gruyter GmbH
Gunput, S T G, Ligtenberg, A J M, Terlouw, B, Brouwer, M, Veerman, E C I & Wouters, D 2015, ' Complement activation by salivary agglutinin is secretor status dependent ', Biological Chemistry, vol. 396, no. 1, pp. 35-43 . https://doi.org/10.1515/hsz-2014-0200
Biological chemistry, 396(1), 35-43. De Gruyter
Biological chemistry, 396(1), 35-43. Walter de Gruyter GmbH
After mucosal damage or gingival inflammation, complement proteins leak into the oral cavity and mix with salivary proteins such as salivary agglutinin (SAG/gp-340/DMBT1). This protein is encoded by the gene Deleted in Malignant Brain Tumors 1 (DMBT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d1932691a2bb89ae6bc2129b29d1d9
https://doi.org/10.1515/hsz-2014-0200
https://doi.org/10.1515/hsz-2014-0200
Autor:
Sergey N Ustinov, Jack Han-Hsing Lin, Antoon J. M. Ligtenberg, Niclas G. Karlsson, Samah M. A. Issa, Anthony P. Moran
Publikováno v:
Glycobiology, 20(8), 1046-1057. Oxford University Press
Issa, S, Moran, A P, Ustinov, S N, Lin, J H, Ligtenberg, A J & Karlsson, N G 2010, ' O-linked oligosaccharides from salivary agglutinin: Helicobacter pylori binding sialyl-Lewis x and Lewis b are terminating moieties on hyperfucosylated oligo-N-acetyllactosamine ', Glycobiology, vol. 20, no. 8, pp. 1046-1057 . https://doi.org/10.1093/glycob/cwq066
Issa, S, Moran, A P, Ustinov, S N, Lin, J H, Ligtenberg, A J & Karlsson, N G 2010, ' O-linked oligosaccharides from salivary agglutinin: Helicobacter pylori binding sialyl-Lewis x and Lewis b are terminating moieties on hyperfucosylated oligo-N-acetyllactosamine ', Glycobiology, vol. 20, no. 8, pp. 1046-1057 . https://doi.org/10.1093/glycob/cwq066
Salivary agglutinin plays a vital biological role modulating the protective effect in the oral cavity by interacting with a broad range of oral pathogens. Here, we describe the first characterization of the O-linked oligosaccharides of salivary agglu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ef49cee79026519f1ab8b31343f17c
https://doi.org/10.1093/glycob/cwq066
https://doi.org/10.1093/glycob/cwq066
Autor:
Caroline End, Philip Rosenstiel, Annemarie Poustka, Antoon J. M. Ligtenberg, Gaby Bergmann, Melanie Hudler, Christian Sina, Floris J. Bikker, Frank Autschbach, Nikolaus Gassler, Arie V. Nieuw Amerongen, Marcus Renner, Uffe Holmskov, Axel Benner, Andre Franke, Stefan Lyer, Stefan Schreiber, Jan Mollenhauer, Mathias Hafner, Peter Schirmacher, Burkhard Helmke, Petra Kioschis, Stephanie Blaich
Publikováno v:
European Journal of Immunology. 39:833-842
Deleted in malignant brain tumors 1 (DMBT1) is a secreted glycoprotein displaying a broad bacterial-binding spectrum. Recent functional and genetic studies linked DMBT1 to the suppression of LPS-induced TLR4-mediated NF-kappaB activation and to the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d109f8ff296fb0ad510131f675f8e8b5
https://doi.org/10.1002/eji.200838689
https://doi.org/10.1002/eji.200838689
Publikováno v:
Leito, J T D, Ligtenberg, A J M, Nazmi, K & Veerman, E C I 2009, ' Identification of salivary components that induce transition of hyphae to yeast in Candida albicans ', FEMS Yeast Research, vol. 9, no. 7, pp. 1102-1110 . https://doi.org/10.1111/j.1567-1364.2009.00575.x
FEMS Yeast Research, 9(7), 1102-1110. Wiley-Blackwell
FEMS Yeast Research, 9(7), 1102-1110. Oxford University Press
FEMS Yeast Research, 9(7), 1102-1110. Wiley-Blackwell
FEMS Yeast Research, 9(7), 1102-1110. Oxford University Press
Candida albicans, the major human fungal pathogen, undergoes a reversible morphological transition from single yeast cells to pseudohyphae and hyphae filaments. The hyphae form is considered the most invasive form of the fungus. The purpose of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c5a7b70438c33fbc2286bce465b641
https://research.vu.nl/en/publications/c842bc69-fc9b-4d1d-9dd4-28612df4f903
https://research.vu.nl/en/publications/c842bc69-fc9b-4d1d-9dd4-28612df4f903