Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Antony Wamiru"'
Autor:
Wei Jiang, Dongdong Wang, Brice A. P. Wilson, Unwoo Kang, Heidi R. Bokesch, Emily A. Smith, Antony Wamiru, Ekaterina I. Goncharova, Donna Voeller, Stanley Lipkowitz, Barry R. O’Keefe, Kirk R. Gustafson
Publikováno v:
Marine Drugs, Vol 19, Iss 7, p 361 (2021)
An extract of the coralline demosponge Astrosclera willeyana inhibited the ubiquitin ligase activity of the immunomodulatory protein Cbl-b. The bioassay-guided separation of the extract provided ten active compounds, including three new N-methyladeni
Externí odkaz:
https://doaj.org/article/e88285871d6e4f548affd387fbd4536c
Autor:
Brice A. P. Wilson, Ning Li, Juliana A. Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Emily A. Smith, Antony Wamiru, Rohan Shah, Ekaterina I. Goncharova, John A. Beutler, Tanja Grkovic, Ping Zhang, Barry R. O’Keefe
Publikováno v:
ACS Pharmacology & Translational Science. 6:633-650
Autor:
Quan T. Khong, Donghao Li, Brice A. P. Wilson, Kalina Ranguelova, Masoumeh Dalilian, Emily A. Smith, Antony Wamiru, Ekaterina I. Goncharova, Tanja Grkovic, Donna Voeller, Stanley Lipkowitz, Martin J. Schnermann, Barry R. O’Keefe, Lin Du
Publikováno v:
Organic Letters. 24:9468-9472
A new dimeric alkaloid plakoramine A [(±)
Autor:
Heidi R. Bokesch, Kirk R. Gustafson, Emily A. Smith, Antony Wamiru, Dongdong Wang, Barry R. O'Keefe, Brice A P Wilson, Unwoo Kang, Wei Jiang, Ekaterina I. Goncharova, Donna Voeller, Stanley Lipkowitz
Publikováno v:
Marine Drugs
Volume 19
Issue 7
Marine Drugs, Vol 19, Iss 361, p 361 (2021)
Volume 19
Issue 7
Marine Drugs, Vol 19, Iss 361, p 361 (2021)
An extract of the coralline demosponge Astrosclera willeyana inhibited the ubiquitin ligase activity of the immunomodulatory protein Cbl-b. The bioassay-guided separation of the extract provided ten active compounds, including three new N-methyladeni
Autor:
Donna Voeller, Brice A P Wilson, Emily A. Smith, Ekaterina I. Goncharova, Stanley Lipkowitz, Barry R. O'Keefe, Gang Liu, Antony Wamiru
Publikováno v:
SLAS Discov
The transfer of the small protein ubiquitin to a target protein is an intricately orchestrated process called ubiquitination that results in modulation of protein function or stability. Proper regulation of ubiquitination is essential, and dysregulat
Autor:
Antony Wamiru, Alexander P. Gorka, Heidi R. Bokesch, Kirk R. Gustafson, Barry R. O'Keefe, Martin J. Schnermann, A. Jonathan Singh
Publikováno v:
Journal of Natural Products. 81:2750-2755
Fluorescent small molecules are important tools in many aspects of modern biology. A two-stage evaluation process involving fluorescence screening and live-cell imaging was developed to facilitate the identification of new fluorescent probes from ext
Autor:
Laura K. Cartner, Gordon L. Hager, Angie B. Dull, James B. McMahon, Ekaterina I. Goncharova, Anuja A. George, Jason R. Evans, Antony Wamiru
Publikováno v:
SLAS Discovery. 19:242-252
We have completed a robust high-content imaging screen for novel estrogen receptor α (ERα) agonists and antagonists by quantitation of cytoplasmic to nuclear translocation of an estrogen receptor chimera in 384-well plates. The screen was very robu
Autor:
James B. McMahon, Young Ho Kim, KiHwan Bae, John A. Beutler, Antony Wamiru, Stuart F. J. Le Grice, Nguyen Tien Dat, Marion K. Bona
Publikováno v:
Journal of Natural Products. 70:839-841
A new dimeric lactone, ardimerin digallate (1), was isolated from the whole plants of Ardisia japonica, along with six known constituents. The structure of 1 was established on the basis of spectroscopic analysis including 1D- and 2D-NMR techniques.
Autor:
Stuart F.J. Le Grice, Antony Wamiru, John A. Beutler, Tawnya C. McKee, James B. McMahon, Heidi R. Bokesch
Three new galloyl arbutins, hyemalosides A-C (1-3), along with nine known compounds were isolated from the evergreen tree Eugenia hyemalis. The structures of compounds 1-3 were determined by analysis of NMR and MS data. Compounds 1-3 inhibited HIV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1033c07b95df320c2ed5c2788879cabc
https://europepmc.org/articles/PMC2586124/
https://europepmc.org/articles/PMC2586124/
Autor:
Ute Möllmann, John A. Beutler, Christophe Marchand, Yves Pommier, Stuart F. J. Le Grice, Lothar Heinisch, Antony Wamiru, John W. Mellors, Scott R. Budihas
Publikováno v:
Antimicrobial agents and chemotherapy. 52(1)
A series of 29 madurahydroxylactone derivatives was evaluated for dual inhibition of human immunodeficiency virus type 1 (HIV-1) integrase and RNase H. While most of the compounds exhibited similar potencies for both enzymes, two of the derivatives s