Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Antony K, Chen"'
Autor:
Ruiting Wang, Fengling Chen, Qian Chen, Xin Wan, Minglei Shi, Antony K. Chen, Zhao Ma, Guohong Li, Min Wang, Yachen Ying, Qinyao Liu, Hu Li, Xu Zhang, Jinbiao Ma, Jiayun Zhong, Meihong Chen, Michael Q. Zhang, Yong Zhang, Yang Chen, Dahai Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Pioneer transcription factors (TFs) have been proposed to act as protein anchors to orchestrate cell type-specific 3D genome architecture. MyoD is a pioneer TF for myogenic lineage specification. Here the authors provide further support for the role
Externí odkaz:
https://doaj.org/article/b07f9652a2354c428d81937cb7ac0952
Autor:
Ming Jin, Shui-Jing Tang, Jin-Hui Chen, Xiao-Chong Yu, Haowen Shu, Yuansheng Tao, Antony K. Chen, Qihuang Gong, Xingjun Wang, Yun-Feng Xiao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Suppressing 1/f-shaped low-frequency noise is critical but fundamentally challenging to both electrical and optical transducers. Here, the authors demonstrate a 1/f-noise-free optical sensor with integrated CMOS-compatible heterodyne interferometer a
Externí odkaz:
https://doaj.org/article/55b17c08e2bb4a87b74f31eed5b9ab1e
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 2, Pp 119-128 (2019)
Chromatin conformation, localization, and dynamics are crucial regulators of cellular behaviors. Although fluorescence in situ hybridization-based techniques have been widely utilized for investigating chromatin architectures in healthy and diseased
Externí odkaz:
https://doaj.org/article/e24729cbe2994ce7aac6317d78c9ba45
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101801- (2020)
Summary: Nucleic acids, aside from being best known as the carrier of genetic information, are versatile biomaterials for constructing nanoscopic devices for biointerfacing, owing to their unique properties such as specific base pairing and predictab
Externí odkaz:
https://doaj.org/article/8a63f78d430f458899542057cb5a0f7f
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 15, Iss 5, Pp 279-286 (2017)
With numerous advancements in novel biochemical techniques, our knowledge of the role of RNAs in the regulation of cellular physiology and pathology has grown significantly over the past several decades. Nevertheless, detailed information regarding R
Externí odkaz:
https://doaj.org/article/9ae32e63922a48ef81d4b3882150b2c5
Publikováno v:
Protein & Cell, Vol 9, Iss 7, Pp 640-651 (2017)
Abstract We recently reported an unconventional mechanism by which miRNAs inhibit HIV-1 viral production. This occurs when miRNAs bind nonspecifically to the viral structural protein Gag, interfering with viral RNA-mediated Gag assembly at the plasma
Externí odkaz:
https://doaj.org/article/bab271869b784deb9a42e3c69975ccb7
Autor:
Mingming Chen, Zhao Ma, Xiaotian Wu, Shiqi Mao, Yantao Yang, Jie Tan, Christopher J. Krueger, Antony K. Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Analysis of RNA dynamics and localization at the single-molecule level in living cells has been predominantly achieved by engineering target RNAs with large insertions of tandem repeat sequences that are bound by protein-based or oligonucleo
Externí odkaz:
https://doaj.org/article/830019b1912f4a87a66e26d327bea6da
Autor:
Xiaohua Yu, Yong Zhang, Tingting Li, Zhao Ma, Haixue Jia, Qian Chen, Yixia Zhao, Lili Zhai, Ran Zhong, Changyin Li, Xiaoting Zou, Jiao Meng, Antony K. Chen, Pier Lorenzo Puri, Meihong Chen, Dahai Zhu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Long non-coding RNAs are important regulators of many diverse biological processes. Here the authors describe Linc-RAM, which regulates myogenesis by binding MyoD and promoting the assembly of the MyoD–Baf60c–Brg1 complex at target genes.
Externí odkaz:
https://doaj.org/article/1c57eaf4e6a84d45965f21b426993e40
Autor:
Ji Dong, Xinglong Wu, Xin Zhou, Yuan Gao, Changliang Wang, Wendong Wang, Weiya He, Jingyun Li, Wenjun Deng, Jiayu Liao, Xiaotian Wu, Yongqu Lu, Antony K Chen, Lu Wen, Wei Fu, Fuchou Tang
Publikováno v:
Protein & Cell.
Molecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics and single-cell assay for transposase accessible chromatin sequencing (scATA
Publikováno v:
ACS Nano. 15:14338-14346
Bimolecular Fluorescence Complementation (BiFC) is a versatile approach for intracellular analysis of protein-protein interactions (PPIs), but the tendency of the split fluorescent protein (FP) fragments to self-assemble when brought into close proxi