Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Antony J. Mullen"'
Autor:
P. J. Townsend, Paul J.R. Barton, Nigel J. Brand, Pankaj K. Bhavsar, Magdi H. Yacoub, Antony J. Mullen, Martin E. Cullen, David A.M. Norman
Publikováno v:
Genomics. 57:102-109
Based on chromosomal mapping data, we recently revealed an unexpected linkage of troponin genes in the human genome: the six genes encoding striated muscle troponin I and troponin T isoforms are located at three chromosomal sites, each of which carri
Autor:
Therese H. Røst, Rolf K. Berge, Hege Wergedahl, Antony J. Mullen, Pål Aukrust, Heidi Glosli, Oddrun Anita Gudbrandsen, Hans Prydz, Bente Halvorsen
Publikováno v:
Biochimica et biophysica acta. 1734(3)
The present study investigated the hepatic regulation of fatty acid metabolism in hTNFalpha transgenic mice. Reduced hepatic mRNA levels and activities of carnitine palmitoyltransferase-II (CPT-II) and mitochondrial HMG-CoA synthase were observed, ac
Autor:
Martin E. Cullen, Pankaj K. Bhavsar, Antony J. Mullen, Paul J.R. Barton, Nigel J. Brand, Kimberley A. Dellow
Publikováno v:
Myofibrillogenesis ISBN: 9781461266587
In spite of considerable advances, understanding the mechanisms that regulate correct temporal and spatial gene expression during development remains one of the major challenges of molecular biology. During cardiac development, intricate patterns of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317d8d066e899541dce749f797c85beb
https://doi.org/10.1007/978-1-4612-0199-1_8
https://doi.org/10.1007/978-1-4612-0199-1_8
Autor:
Paul B. J. Burton, Magdi H. Yacoub, Paul J.R. Barton, Emma J. Birks, Antony J. Mullen, V. J. Owen
Publikováno v:
European heart journal. 22(12)
Regulators of G-protein Signalling (RGS) proteins have been shown to limit in vitro signalling of G proteins. In common with end-stage heart failure, we have recently shown that upregulation of the inhibitory G-protein, Gialpha, occurs in acutely fai
Autor:
Emma J. Birks, Paul B. J. Burton, V. J. Owen, Magdi H. Yacoub, Nicholas R. Banner, Paul J.R. Barton, Diane Hunt, Antony J. Mullen
Publikováno v:
Europe PubMed Central
Background —Myocardial dysfunction is a common and important problem in donor hearts. The mechanisms responsible remain unclear. We have studied the cytokines tumor necrosis factor (TNF)-α and interleukin-6 (IL-6) in the myocardium and serum from
Autor:
Emma J. Birks, Paul B. J. Burton, Virginia Owen, Antony J. Mullen, Diane Hunt, Nicholas R. Banner, Paul J. R. Barton, Magdi H. Yacoub
Publikováno v:
Circulation. 102
Background —Myocardial dysfunction is a common and important problem in donor hearts. The mechanisms responsible remain unclear. We have studied the cytokines tumor necrosis factor (TNF)-α and interleukin-6 (IL-6) in the myocardium and serum from
Genes encoding troponin I and troponin T are organized as three paralogous pairs in the mouse genome
Autor:
Gurtej K. Dhoot, Martin E. Cullen, Antony J. Mullen, Paul J.R. Barton, Jean-Louis Guénet, Dominique Simon-Chazottes
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 11(10)
Autor:
Paul J.R. Barton, Antony J. Mullen
Publikováno v:
Gene. 242(1-2)
Three troponin I genes have been identified in vertebrates that encode the isoforms expressed in adult cardiac muscle (TNNI3), slow skeletal muscle (TNNI1) and fast skeletal muscle (TNNI2), respectively. While the organization and regulation of human
Publikováno v:
Biochemical Society Transactions. 28:A176-A176