Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Antony J. Fairbanks"'
Autor:
Antony J. Fairbanks
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 416-429 (2018)
N-Glycan oxazolines have found widespread use as activated donor substrates for endo-β-N-acetylglucosaminidase (ENGase) enzymes, an important application that has correspondingly stimulated interest in their production, both by total synthesis and b
Externí odkaz:
https://doaj.org/article/c98b905f07f140e683d2a38b81204f41
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 11-24 (2018)
Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as o
Externí odkaz:
https://doaj.org/article/be198a5cd0524d829c4ede16f240514e
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 8, Pp o1401-o1401 (2008)
The title compound, C21H26O10S, was synthesized in a single step from mannose pentaacetate. The molecular structure confirms the α configuration of the anomeric thioaryl substituent. Spectroscopic and melting-point data obtained for the title compou
Externí odkaz:
https://doaj.org/article/13170240966b453197e118f4283e8a67
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 1, Pp o236-o236 (2008)
The title compound, C40H31NO11S·0.53CH2Cl2·0.38C4H10O, was synthesized in two steps from mannose pentaacetate and single crystals were grown by slow evaporation. The structure was determined by single-crystal X-ray diffraction, confirming the α-co
Externí odkaz:
https://doaj.org/article/ba8f70853bf74895994c01d41c2bf628
Publikováno v:
Organic Letters. 25:1989-1993
Publikováno v:
Chemical Science. 13:4122-4130
Un-protected 2-acetamido sugars are stereoselectively converted into 1,2-trans glycosides and (1→6)-linked disaccharides without any protecting groups. Reaction proceeds via intermediate oxazolines which react with acceptors under acid catalysis.
Autor:
Andrea Mascherpa, Nozomii Ishii, Ayelen Tayagui, Jiang Liu, Matthieu Sollogoub, Antony J. Fairbanks
Publikováno v:
Chemistry – A European Journal. 29
β-Cyclodextrin (β-CD) and derivatives are approved therapeutics in30 clinical settings. β-CDs have also shown promise as therapeutics for treatment of some lysosomal storage disorders, such as Niemann-Pick disease type C, and other disease states
Autor:
Xin Qiu, Antony J. Fairbanks
Publikováno v:
Organic Letters. 22:2490-2493
Reducing sugars may be directly converted into the corresponding para-nitrophenyl (pNP) glycosides using 2-chloro-1,3-dimethylimidazolinium chloride (DMC), para-nitrophenol, and a suitable base in aqueous solution. The reaction is stereoselective for
Autor:
Antony J. Fairbanks
Publikováno v:
Current Opinion in Chemical Biology. 53:9-15
The majority of the world's best-selling biotherapeutics are glycoproteins. However their production using cellular expression systems invariably produces inseparable mixtures of materials which differ in their attached carbohydrates. As in many case
Autor:
Moritz Lassé, Anja R. Stampfli, Thomas Orban, Roshit K. Bothara, Juliet A. Gerrard, Antony J. Fairbanks, Neil R. Pattinson, Renwick C.J. Dobson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130117