Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Antony J Workman"'
Autor:
Erick A Perez Alday, Michael A Colman, Philip Langley, Timothy D Butters, Jonathan Higham, Antony J Workman, Jules C Hancox, Henggui Zhang
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 1, p e1004026 (2015)
Rapid atrial arrhythmias such as atrial fibrillation (AF) predispose to ventricular arrhythmias, sudden cardiac death and stroke. Identifying the origin of atrial ectopic activity from the electrocardiogram (ECG) can help to diagnose the early onset
Externí odkaz:
https://doaj.org/article/4eac07f94f964133a16c8d1881f28eb0
Autor:
Sandeep V. Pandit, Antony J. Workman
Publikováno v:
Clinical Medicine Insights: Cardiology, Vol 2016, Iss Suppl. 1, Pp 41-46 (2016)
Externí odkaz:
https://doaj.org/article/4b8b1c341bb5495d817406310f8a167a
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: The development of improved diagnosis, management, and treatment strategies for human atrial fibrillation (AF) is a significant and important challenge in order to improve quality of life for millions and reduce the substantial social-e
Externí odkaz:
https://doaj.org/article/3ecd27f3040e4070802dbd574f442478
Autor:
S. Nashitha Kabir, Jasmeet S. Reyat, Antony J. Workman, Priyanka Saxena, Dannie Fobian, Davor Pavlovic, Larissa Fabritz, Clara Apicella, Stefan M. Kuhlmann, Godfrey L. Smith, Paulus Kirchhof, Molly O’Reilly, Andrew P. Holmes, Fahima Syeda, Suranjana Gupta, Christopher O’Shea
Publikováno v:
Heart Rhythm. 18:1212-1220
Background Although atrial fibrillation ablation is increasingly used for rhythm control therapy, antiarrhythmic drugs (AADs) are commonly used, either alone or in combination with ablation. The effectiveness of AADs is highly variable. Previous work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e783579a1098674f75a0a9e07eb3699
https://doi.org/10.1016/j.hrthm.2021.03.016
https://doi.org/10.1016/j.hrthm.2021.03.016
Publikováno v:
Pflugers Archiv : European journal of physiology. 474(12)
Atrial fibrillation (AF) from elevated adrenergic activity may involve increased atrial L-type Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38eca582a159191d934b0246a9226219
https://pubmed.ncbi.nlm.nih.gov/36131146
https://pubmed.ncbi.nlm.nih.gov/36131146
Autor:
Godfrey L. Smith, Sarah Kettlewell, Priyanka Saxena, Antony J. Workman, John Dempster, Michael A. Colman, Rachel C. Myles
Publikováno v:
The Journal of Physiology. 597:3619-3638
KEY POINTS Early-afterdepolarizations (EADs) are abnormal action potential oscillations and a known cause of cardiac arrhythmias. Ventricular EADs involve reactivation of a Ca2+ current (ICaL ) in its 'window region' voltage range. However, electrica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e8b77eff69215dc78b9faf0e136734
https://doi.org/10.1113/jp277827
https://doi.org/10.1113/jp277827
Autor:
Sarah, Kettlewell, Priyanka, Saxena, John, Dempster, Michael A, Colman, Rachel C, Myles, Godfrey L, Smith, Antony J, Workman
Publikováno v:
The Journal of Physiology
Key points Early‐afterdepolarizations (EADs) are abnormal action potential oscillations and a known cause of cardiac arrhythmias. Ventricular EADs involve reactivation of a Ca2+ current (I CaL) in its ‘window region’ voltage range. However, ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a66d8938a198ec6d54e5ec216c8b722
https://pubmed.ncbi.nlm.nih.gov/31093979
https://pubmed.ncbi.nlm.nih.gov/31093979
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: The development of improved diagnosis, management and treatment strategies for human atrial fibrillation (AF) is a significant and important challenge in order to improve quality of life for millions and reduce the substantial social-ec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2344f4f7c2ad6b9687308de39713023b
Autor:
Arun V. Holden, Antony J. Workman, Irina V. Biktasheva, Sanjay Kharche, Henggui Zhang, Michael A. Colman, Tomas Stary, Andrew C. Rankin
Publikováno v:
EP Europace. 16:1524-1533
Aims Atrial anti-arrhythmic effects of β-adrenoceptor antagonists (β-blockers) may involve both a suppression of pro-arrhythmic effects of catecholamines, and an adaptational electrophysiological response to chronic β-blocker use; so-called ‘pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3835e231a5d37ed1b9cae4e3ffe44af
https://doi.org/10.1093/europace/euu084
https://doi.org/10.1093/europace/euu084
Publikováno v:
CinC
Atrial fibrillation is the most common arrhythmia, yet\ud treatment strategies are sub-optimal due to incomplete\ud understanding of the underlying mechanisms. Spatiotemporal\ud sub-cellular calcium cycling may play a critical\ud role in the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c9615812f675bf38ae389ad14ecb1a
https://doi.org/10.22489/cinc.2016.067-421
https://doi.org/10.22489/cinc.2016.067-421