Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Antony J, Fairbanks"'
Publikováno v:
Organic Letters. 25:1989-1993
Autor:
Antony J. Fairbanks
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 416-429 (2018)
N-Glycan oxazolines have found widespread use as activated donor substrates for endo-β-N-acetylglucosaminidase (ENGase) enzymes, an important application that has correspondingly stimulated interest in their production, both by total synthesis and b
Externí odkaz:
https://doaj.org/article/c98b905f07f140e683d2a38b81204f41
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 11-24 (2018)
Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as o
Externí odkaz:
https://doaj.org/article/be198a5cd0524d829c4ede16f240514e
Publikováno v:
Chemical Science. 13:4122-4130
Un-protected 2-acetamido sugars are stereoselectively converted into 1,2-trans glycosides and (1→6)-linked disaccharides without any protecting groups. Reaction proceeds via intermediate oxazolines which react with acceptors under acid catalysis.
Autor:
Andrea Mascherpa, Nozomii Ishii, Ayelen Tayagui, Jiang Liu, Matthieu Sollogoub, Antony J. Fairbanks
Publikováno v:
Chemistry – A European Journal. 29
β-Cyclodextrin (β-CD) and derivatives are approved therapeutics in30 clinical settings. β-CDs have also shown promise as therapeutics for treatment of some lysosomal storage disorders, such as Niemann-Pick disease type C, and other disease states
Autor:
Xin Qiu, Antony J. Fairbanks
Publikováno v:
Organic Letters. 22:2490-2493
Reducing sugars may be directly converted into the corresponding para-nitrophenyl (pNP) glycosides using 2-chloro-1,3-dimethylimidazolinium chloride (DMC), para-nitrophenol, and a suitable base in aqueous solution. The reaction is stereoselective for
Autor:
Antony J. Fairbanks
Publikováno v:
Current Opinion in Chemical Biology. 53:9-15
The majority of the world's best-selling biotherapeutics are glycoproteins. However their production using cellular expression systems invariably produces inseparable mixtures of materials which differ in their attached carbohydrates. As in many case
Autor:
Moritz Lassé, Anja R. Stampfli, Thomas Orban, Roshit K. Bothara, Juliet A. Gerrard, Antony J. Fairbanks, Neil R. Pattinson, Renwick C.J. Dobson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130117
Autor:
Antony J. Fairbanks
Publikováno v:
Comprehensive Glycoscience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54860b131ae24f4888e82c4e885313b5
https://doi.org/10.1016/b978-0-12-409547-2.14950-9
https://doi.org/10.1016/b978-0-12-409547-2.14950-9
Autor:
Antony J. Fairbanks
Publikováno v:
Carbohydrate research. 499
2-Chloro-1,3-dimethylimidazolinium chloride (DMC, herein also referred to as Shoda's reagent) and its derivatives are useful for numerous synthetic transformations in which the anomeric centre of unprotected reducing sugars is selectively activated i