Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Antony Hynes-Allen"'
Autor:
Brian Hendrich, Donna Leaford, Gayan Balasooriya, Paul Bertone, Nicola Reynolds, Antony Hynes-Allen, Mali Salmon-Divon, Axel Behrens, Heidi Dvinge
Publikováno v:
The EMBO Journal. 31:593-605
Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages requires strict control of gene expression to coordinate the downregulation of lineage inappropriate genes while enabling th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ce6c241c2c9e153e42a56fadb1eb306
https://doi.org/10.1038/emboj.2011.431
https://doi.org/10.1038/emboj.2011.431
Autor:
Kentaro Nakagawa, Peter Humphreys, Antony Hynes-Allen, Aoife O'Shaughnessy, Jason Signolet, Ita Costello, Paul Bertone, Donna Leaford, Paulina A. Latos, Tuezer Kalkan, Brian Hendrich, Philip Brennecke, John Strouboulis, William Mansfield, Nicola Reynolds, Axel Behrens, Olukunbi Mosaku, Remco Loos
Publikováno v:
Reynolds, N, Latos, P, Hynes-Allen, A, Loos, R, Leaford, D, O'Shaughnessy, A, Mosaku, O, Signolet, J, Brennecke, P, Kalkan, T, Costello, I, Humphreys, P, Mansfield, W, Nakagawa, K, Strouboulis, J, Behrens, A, Bertone, P & Hendrich, B 2012, ' NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment ', Cell Stem Cell, vol. 10, no. 5, pp. 583-594 . https://doi.org/10.1016/j.stem.2012.02.020
Cell Stem Cell
Cell Stem Cell
Summary Transcriptional heterogeneity within embryonic stem cell (ESC) populations has been suggested as a mechanism by which a seemingly homogeneous cell population can initiate differentiation into an array of different cell types. Chromatin remode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f914d8871537c52d07f328be6044a560
https://www.repository.cam.ac.uk/handle/1810/270530
https://www.repository.cam.ac.uk/handle/1810/270530
Autor:
Nicola, Reynolds, Mali, Salmon-Divon, Heidi, Dvinge, Antony, Hynes-Allen, Gayan, Balasooriya, Donna, Leaford, Axel, Behrens, Paul, Bertone, Brian, Hendrich
Publikováno v:
The EMBO Journal
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression The NURD and Polycomb complexes PRC1 and PRC2 have been implicated in stem cell differentiation although their molecular roles are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af3eeedff1100dbead888bdf552fc0b6
https://pubmed.ncbi.nlm.nih.gov/22139358
https://pubmed.ncbi.nlm.nih.gov/22139358