Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Antony Cousins"'
Autor:
Lennart Lenk, Michela Carlet, Fotini Vogiatzi, Lea Spory, Dorothee Winterberg, Antony Cousins, Michaela Vossen-Gajcy, Olta Ibruli, Christian Vokuhl, Gunnar Cario, Omar El Ayoubi, Lisa Kramer, Matthias Ritgen, Monika Brüggemann, Robert Häsler, Martin Schrappe, Stephan Fuhrmann, Christina Halsey, Irmela Jeremias, Elias Hobeika, Hassan Jumaa, Ameera Alsadeq, Denis M. Schewe
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Lenk et al find that the preB cell receptor (preBCR) is associated with infiltration and relapse of acute lymphoblastic leukemia in the central nervous system (CNS). They also show that downregulation of preBCR component CD79a reduces the engraftment
Externí odkaz:
https://doaj.org/article/45d481a21f3e44e49b4f84076c7e9181
Autor:
Michaela Vossen-Gajcy, Olta Ibruli, Martin Schrappe, Antony Cousins, Lisa Kramer, Irmela Jeremias, Dorothee Winterberg, Matthias Ritgen, Fotini Vogiatzi, Stephan Fuhrmann, Denis M. Schewe, Robert Häsler, Hassan Jumaa, Christian Vokuhl, Monika Brüggemann, Chris Halsey, Lennart Lenk, Omar El Ayoubi, Lea Spory, A Alsadeq, Gunnar Cario, Elias Hobeika, Michela Carlet
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Comm. Biol. 4:73 (2021)
communications biology
Communications Biology, Vol 4, Iss 1, Pp 1-6 (2021)
Comm. Biol. 4:73 (2021)
communications biology
Central nervous system (CNS) involvement remains a challenge in the diagnosis and treatment of acute lymphoblastic leukemia (ALL). In this study, we identify CD79a (also known as Igα), a signaling component of the preB cell receptor (preBCR), to be
Autor:
Denis M. Schewe, Hassan Jumaa, A Alsadeq, Elias Hobeika, I Jeremias, Christina Halsey, M Carlet, Antony Cousins, Lennart Lenk, Gunnar Cario
Publikováno v:
Klinische Pädiatrie.
Autor:
Justin R. Cross, Orianne Olivares, Jonatan Fernández-García, Angela M. Savino, Sara Isabel Fernandes, Shani Barel, Cornelia Eckert, Inbal Mor, Pawel Herzyk, Jurre Kamphorst, Liron Frishman, Antony Cousins, Michael G. Kharas, Shai Izraeli, Ifat Abramovich, Sudha Janaki-Raman, Ersilia Barin, Eyal Gottlieb, Elke Markert, Gillian M. Mackay, Christina Halsey, Sergey Tumanov, Ifat Geron, Yehudit Birger, Anna Zemlyansky, Michela Bardini
Publikováno v:
Nature Cancer
Nat Cancer
Nat Cancer
Metabolic reprogramming is a key hallmark of cancer, but less is known about metabolic plasticity of the same tumor at different sites. Here, we investigated the metabolic adaptation of leukemia in two different microenvironments, the bone marrow and
Autor:
Yasar Mehmood Yousafzai, Brenda Gibson, Antony Cousins, Christina Halsey, Alison Spence, Nicholas Heaney, Wendy Taylor, Linda Smith, Saeeda Bhatti, Amanda Smith, Sandra Chudleigh, Frances Fee, Mary Gardiner, Gerard J. Graham
Publikováno v:
Leukemia research. 87
No abstract available.
Autor:
Felix Seyfried, A Alsadeq, Christian Vokuhl, Klaus-Michael Debatin, Hassan Jumaa, Anila Vadakumchery, LH Meyer, Denis M. Schewe, Elias Hobeika, Martin Schrappe, Christina Halsey, Fotini Vogiatzi, Antony Cousins, Ahmad Khadour, Lennart Lenk, Gunnar Cario
Publikováno v:
Blood
TO THE EDITOR: Central nervous system (CNS) involvement in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is rarely detected at initial presentation.[1][1] Nevertheless, CNS relapse most frequently occurs in children who were initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8208912490525846e625047919bd8757
https://europepmc.org/articles/PMC6238156/
https://europepmc.org/articles/PMC6238156/
Publikováno v:
The Lancet. 389:S35
Background Acute lymphoblastic leukaemia is the most common childhood cancer. Despite advances in treatment, meningeal-infiltrating CNS disease (found in up to 90% of children if untreated) remains a challenge. Every child with acute lymphoblastic le