Gene expression during the first 28 days of axolotl limb regeneration I: Experimental design and global analysis of gene expression

Autor: Ken Muneoka, Alex Palumbo, Antony Athippozhy, Radha Nagarajan, David M. Gardiner, Arnold J. Stromberg, S. Randal Voss

Publikováno v: Regeneration. 2:120-136

While it is appreciated that global gene expression analyses can provide novel insights about complex biological processes, experiments are generally insufficiently powered to achieve this goal. Here we report the results of a robust microarray exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13bfcc9757ceba1b30f27584247a9656
https://doi.org/10.1002/reg2.37

Characterization of in vitro transcriptional responses of dorsal root ganglia cultured in the presence and absence of blastema cells from regenerating salamander limbs

Autor: Antony Athippozhy, James R. Monaghan, Jeffrey Lehrberg, David M. Gardiner, S. Randal Voss

Publikováno v: Regeneration (Oxford, England), vol 1, iss 2
Athippozhy, A; Lehrberg, J; Monaghan, JR; Gardiner, DM; & Voss, SR. (2014). Characterization of in vitro transcriptional responses of dorsal root ganglia cultured in the presence and absence of blastema cells from regenerating salamander limbs.. Regeneration (Oxford, England), 1(2), 1-10. doi: 10.1002/reg2.14. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6882n0v3

During salamander limb regeneration, nerves provide signals that induce the formation of a mass of proliferative cells called the blastema. To better understand these signals, we developed a blastema-dorsal root ganglia (DRG) co-culture model system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3071c576f4cdd41972f6dd5bfc4c4a78
https://doi.org/10.1002/reg2.14

Using Ambystoma mexicanum (Mexican Axolotl) Embryos, Chemical Genetics, and Microarray Analysis to Identify Signaling Pathways Associated with Tissue Regeneration

Autor: Jon S. Thorson, S. Randal Voss, Antony Athippozhy, Larissa V. Ponomareva

Amphibian vertebrates are important models in regenerative biology because they present exceptional regenerative capabilities throughout life. However, it takes considerable effort to rear amphibians to juvenile and adult stages for regeneration stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1aa393bda690a08e84bd15e9db349a2
https://europepmc.org/articles/PMC4662883/

Transcriptomics using axolotls

Autor: S Randal, Voss, Antony, Athippozhy, M Ryan, Woodcock

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1290

Microarray and RNA-sequencing technology now exists for the characterization of the Ambystoma mexicanum transcriptome. With sufficient replication, these tools give the opportunity to truly investigate gene expression in a variety of experimental par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7598498e94fa15a72db40735939b425a
https://pubmed.ncbi.nlm.nih.gov/25740496

Gene expression patterns specific to the regenerating limb of the Mexican axolotl

Autor: Antony Athippozhy, Arnold J. Stromberg, S. Randal Voss, Malcolm Maden, Sri Putta, Ashley W. Seifert, David M. Gardiner, James R. Monaghan

Publikováno v: Biology Open
Biology Open, Vol 1, Iss 10, Pp 937-948 (2012)
Biology open, vol 1, iss 10

Summary Salamander limb regeneration is dependent upon tissue interactions that are local to the amputation site. Communication among limb epidermis, peripheral nerves, and mesenchyme coordinate cell migration, cell proliferation, and tissue patterni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec83a1e6c50680500c2d53d7dd8b96d7
https://pubmed.ncbi.nlm.nih.gov/23213371